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Seth E Karol
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NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells
SW Paugh, EJ Bonten, D Savic, LB Ramsey, WE Thierfelder, P Gurung, ...
Nature genetics 47 (6), 607-614, 2015
1642015
Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study
SE Karol, TB Alexander, A Budhraja, SB Pounds, K Canavera, L Wang, ...
The Lancet Oncology 21 (4), 551-560, 2020
1442020
Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia
SE Karol, W Yang, SL Van Driest, TY Chang, S Kaste, E Bowton, ...
Blood 126 (15), 1770-1776, 2015
1172015
Clinical significance of novel subtypes of acute lymphoblastic leukemia in the context of minimal residual disease-directed therapy
S Jeha, J Choi, KG Roberts, D Pei, E Coustan-Smith, H Inaba, JE Rubnitz, ...
Blood Cancer Discovery, 2021
1162021
Antibodies predict pegaspargase allergic reactions and failure of rechallenge
Y Liu, CA Smith, JC Panetta, W Yang, LE Thompson, JP Counts, ...
Journal of clinical oncology 37 (23), 2051-2061, 2019
822019
Genome-wide analysis links NFATC2 with asparaginase hypersensitivity
CA Fernandez, C Smith, W Yang, CG Mullighan, C Qu, E Larsen, ...
Blood 126 (1), 69-75, 2015
822015
Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia
SE Karol, LA Mattano, W Yang, KW Maloney, C Smith, CC Liu, ...
Blood 127 (5), 558-564, 2016
712016
Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia
RJ Autry, SW Paugh, R Carter, L Shi, J Liu, DC Ferguson, CE Lau, ...
Nature Cancer 1 (3), 329-344, 2020
572020
Comparison of genome sequencing and clinical genotyping for pharmacogenes
W Yang, G Wu, U Broeckel, CA Smith, V Turner, CE Haidar, S Wang, ...
Clinical Pharmacology & Therapeutics 100 (4), 380-388, 2016
552016
Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia
ER Finch, CA Smith, W Yang, Y Liu, NM Kornegay, JC Panetta, KR Crews, ...
Pediatric blood & cancer 67 (1), e28040, 2020
542020
Genome‐Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy
Y Liu, CA Fernandez, C Smith, W Yang, C Cheng, JC Panetta, ...
Clinical Pharmacology & Therapeutics 102 (1), 131-140, 2017
542017
Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait
C Liu, W Yang, D Pei, C Cheng, C Smith, W Landier, L Hageman, Y Chen, ...
Clinical Pharmacology & Therapeutics 101 (3), 373-381, 2017
532017
Bone mineral density surveillance for childhood, adolescent, and young adult cancer survivors: evidence-based recommendations from the International Late Effects of Childhood …
JE van Atteveld, RL Mulder, MM van den Heuvel-Eibrink, MM Hudson, ...
The Lancet Diabetes & Endocrinology 9 (9), 622-637, 2021
522021
Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response
SHR Lee, W Yang, Y Gocho, A John, L Rowland, B Smart, H Williams, ...
Nature medicine 29 (1), 170-179, 2023
462023
Prognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy
SE Karol, E Coustan‐Smith, X Cao, SA Shurtleff, SC Raimondi, JK Choi, ...
British journal of haematology 168 (1), 94-101, 2015
462015
Elevated CAIX expression is associated with an increased risk of distant failure in early-stage cervical cancer
JP Kirkpatrick, ZN Rabbani, RC Bentley, ME Hardee, S Karol, J Meyer, ...
Biomarker insights 3, BMI. S570, 2008
402008
Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL
A Talleur, A Qudiemat, JY Métais, D Langfitt, E Mamcarz, JC Crawford, ...
Blood Advances, 2022
332022
Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity
BW Blaser, NR Schwind, S Karol, D Chang, S Shin, S Roychowdhury, ...
Blood 108 (7), 2463-2469, 2006
332006
Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia
SE Karol, E Larsen, C Cheng, X Cao, W Yang, LB Ramsey, ...
Leukemia 31 (6), 1325, 2017
322017
Diabetes mellitus among adult survivors of childhood acute lymphoblastic leukemia: A report from the St. Jude lifetime cohort study
HE Williams, CR Howell, W Chemaitilly, CL Wilson, SE Karol, VG Nolan, ...
Cancer 126 (4), 870-878, 2020
292020
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