NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells SW Paugh, EJ Bonten, D Savic, LB Ramsey, WE Thierfelder, P Gurung, ... Nature genetics 47 (6), 607-614, 2015 | 164 | 2015 |
Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study SE Karol, TB Alexander, A Budhraja, SB Pounds, K Canavera, L Wang, ... The Lancet Oncology 21 (4), 551-560, 2020 | 144 | 2020 |
Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia SE Karol, W Yang, SL Van Driest, TY Chang, S Kaste, E Bowton, ... Blood 126 (15), 1770-1776, 2015 | 117 | 2015 |
Clinical significance of novel subtypes of acute lymphoblastic leukemia in the context of minimal residual disease-directed therapy S Jeha, J Choi, KG Roberts, D Pei, E Coustan-Smith, H Inaba, JE Rubnitz, ... Blood Cancer Discovery, 2021 | 116 | 2021 |
Antibodies predict pegaspargase allergic reactions and failure of rechallenge Y Liu, CA Smith, JC Panetta, W Yang, LE Thompson, JP Counts, ... Journal of clinical oncology 37 (23), 2051-2061, 2019 | 82 | 2019 |
Genome-wide analysis links NFATC2 with asparaginase hypersensitivity CA Fernandez, C Smith, W Yang, CG Mullighan, C Qu, E Larsen, ... Blood 126 (1), 69-75, 2015 | 82 | 2015 |
Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia SE Karol, LA Mattano, W Yang, KW Maloney, C Smith, CC Liu, ... Blood 127 (5), 558-564, 2016 | 71 | 2016 |
Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia RJ Autry, SW Paugh, R Carter, L Shi, J Liu, DC Ferguson, CE Lau, ... Nature Cancer 1 (3), 329-344, 2020 | 57 | 2020 |
Comparison of genome sequencing and clinical genotyping for pharmacogenes W Yang, G Wu, U Broeckel, CA Smith, V Turner, CE Haidar, S Wang, ... Clinical Pharmacology & Therapeutics 100 (4), 380-388, 2016 | 55 | 2016 |
Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia ER Finch, CA Smith, W Yang, Y Liu, NM Kornegay, JC Panetta, KR Crews, ... Pediatric blood & cancer 67 (1), e28040, 2020 | 54 | 2020 |
Genome‐Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy Y Liu, CA Fernandez, C Smith, W Yang, C Cheng, JC Panetta, ... Clinical Pharmacology & Therapeutics 102 (1), 131-140, 2017 | 54 | 2017 |
Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait C Liu, W Yang, D Pei, C Cheng, C Smith, W Landier, L Hageman, Y Chen, ... Clinical Pharmacology & Therapeutics 101 (3), 373-381, 2017 | 53 | 2017 |
Bone mineral density surveillance for childhood, adolescent, and young adult cancer survivors: evidence-based recommendations from the International Late Effects of Childhood … JE van Atteveld, RL Mulder, MM van den Heuvel-Eibrink, MM Hudson, ... The Lancet Diabetes & Endocrinology 9 (9), 622-637, 2021 | 52 | 2021 |
Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response SHR Lee, W Yang, Y Gocho, A John, L Rowland, B Smart, H Williams, ... Nature medicine 29 (1), 170-179, 2023 | 46 | 2023 |
Prognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy SE Karol, E Coustan‐Smith, X Cao, SA Shurtleff, SC Raimondi, JK Choi, ... British journal of haematology 168 (1), 94-101, 2015 | 46 | 2015 |
Elevated CAIX expression is associated with an increased risk of distant failure in early-stage cervical cancer JP Kirkpatrick, ZN Rabbani, RC Bentley, ME Hardee, S Karol, J Meyer, ... Biomarker insights 3, BMI. S570, 2008 | 40 | 2008 |
Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL A Talleur, A Qudiemat, JY Métais, D Langfitt, E Mamcarz, JC Crawford, ... Blood Advances, 2022 | 33 | 2022 |
Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity BW Blaser, NR Schwind, S Karol, D Chang, S Shin, S Roychowdhury, ... Blood 108 (7), 2463-2469, 2006 | 33 | 2006 |
Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia SE Karol, E Larsen, C Cheng, X Cao, W Yang, LB Ramsey, ... Leukemia 31 (6), 1325, 2017 | 32 | 2017 |
Diabetes mellitus among adult survivors of childhood acute lymphoblastic leukemia: A report from the St. Jude lifetime cohort study HE Williams, CR Howell, W Chemaitilly, CL Wilson, SE Karol, VG Nolan, ... Cancer 126 (4), 870-878, 2020 | 29 | 2020 |