Meghan O'Donoghue Altman
Meghan O'Donoghue Altman
Senior Scientist, Nucleix
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Development of DNA aptamers using Cell-SELEX
K Sefah, D Shangguan, X Xiong, MB O'Donoghue, W Tan
Nature protocols 5 (6), 1169, 2010
Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapy
J Wang, G Zhu, M You, E Song, MI Shukoor, K Zhang, MB Altman, Y Chen, ...
ACS nano 6 (6), 5070-5077, 2012
A liposome-based nanostructure for aptamer directed delivery
TW Kang H, O'Donoghue MB, Liu H
Chemical communications 46 (2), 249-251, 2010
DNA aptamer-mediated cell targeting
X Xiong, H Liu, Z Zhao, MB Altman, D Lopez-Colon, CJ Yang, LJ Chang, ...
Angewandte Chemie (International ed. in English) 52 (5), 1472, 2013
A surface energy transfer nanoruler for measuring binding site distances on live cell surfaces
Y Chen, MB O’Donoghue, YF Huang, H Kang, JA Phillips, X Chen, ...
Journal of the American Chemical Society 132 (46), 16559-16570, 2010
Photosensitizer–gold nanorod composite for targeted multimodal therapy
J Wang, M You, G Zhu, MI Shukoor, Z Chen, Z Zhao, MB Altman, Q Yuan, ...
small 9 (21), 3678-3684, 2013
Nanoparticles for multiplex diagnostics and imaging
L Wang, MB O ‘Donoghue, W Tan
Nanomedicine 1 (4), 413-426, 2006
Antibody immunodominance: the key to understanding influenza virus antigenic drift
MO Altman, D Angeletti, JW Yewdell
Viral immunology 31 (2), 142-149, 2018
Absence of Neu5Gc and presence of anti-Neu5Gc Antibodies in humans – an evolutionary perspective.
MO Altman, P Gagneux
Frontiers in Immunology, In press, 2019
Silencing of PTK7 in colon cancer cells: caspase-10-dependent apoptosis via mitochondrial pathway
L Meng, K Sefah, MB O'Donoghue, G Zhu, D Shangguan, A Noorali, ...
PloS one 5 (11), e14018, 2010
Highly fluorescent dye-doped silica nanoparticles increase flow cytometry sensitivity for cancer cell monitoring
MC EstÚvez, MB O’Donoghue, X Chen, W Tan
Nano Research 2, 448-461, 2009
Aptamer‐conjugated nanorods for targeted photothermal therapy of prostate cancer stem cells
J Wang, K Sefah, MB Altman, T Chen, M You, Z Zhao, CZ Huang, W Tan
Chemistry–An Asian Journal 8 (10), 2417-2422, 2013
Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit
MO Altman, M Angel, I KošÝk, NS TrovŃo, SJ Zost, JS Gibbs, L Casalino, RE ...
mBio 10 (2), e00204-19, 2019
Lamprey VLRB response to influenza virus supports universal rules of immunogenicity and antigenicity
MO Altman, JR Bennink, JW Yewdell, BR Herrin
Elife 4, e07467, 2015
Aptamer-nanoparticle assembly for logic-based detection
MI Shukoor, MO Altman, D Han, AT Bayrac, I Ocsoy, Z Zhu, W Tan
ACS applied materials & interfaces 4 (6), 3007-3011, 2012
Self‐assembled aptamer‐based drug carriers for bispecific cytotoxicity to cancer cells
G Zhu, L Meng, M Ye, L Yang, K Sefah, MB O'Donoghue, Y Chen, X Xiong, ...
Chemistry–An Asian Journal 7 (7), 1630-1636, 2012
Single-molecule atomic force microscopy on live cells compares aptamer and antibody rupture forces
MB O’Donoghue, X Shi, X Fang, W Tan
Analytical and bioanalytical chemistry 402, 3205-3209, 2012
Using azobenzene incorporated DNA aptamers to probe molecular binding interactions
JA Phillips, H Liu, MB O’Donoghue, X Xiong, R Wang, M You, K Sefah, ...
Bioconjugate chemistry 22 (2), 282-288, 2011
In vitro neurotoxicity resulting from exposure of cultured neural cells to several types of nanoparticles
SF Larner, J Wang, J Goodman, MB O’Donoghue Altman, M Xin, ...
Journal of Cell Death 10, 1179670717694523, 2017
Nanoparticle–aptamer conjugates for cancer cell targeting and detection
MC EstÚvez, YF Huang, H Kang, MB O’Donoghue, S Bamrungsap, J Yan, ...
Cancer Nanotechnology: Methods and Protocols, 235-248, 2010
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