Christopher A. Klebanoff, M.D.
Christopher A. Klebanoff, M.D.
Verified email at
Cited by
Cited by
Tumor mutational load predicts survival after immunotherapy across multiple cancer types
RM Samstein, CH Lee, AN Shoushtari, MD Hellmann, R Shen, ...
Nature genetics 51 (2), 202-206, 2019
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
L Gattinoni, SE Finkelstein, CA Klebanoff, PA Antony, DC Palmer, ...
The Journal of experimental medicine 202 (7), 907-912, 2005
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
CA Klebanoff, L Gattinoni, P Torabi-Parizi, K Kerstann, AR Cardones, ...
Proceedings of the national academy of sciences 102 (27), 9571-9576, 2005
Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells
L Gattinoni, CA Klebanoff, DC Palmer, C Wrzesinski, K Kerstann, Z Yu, ...
The Journal of clinical investigation 115 (6), 1616-1626, 2005
Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells
WW Overwijk, MR Theoret, SE Finkelstein, DR Surman, LA De Jong, ...
The Journal of experimental medicine 198 (4), 569-580, 2003
CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells
PA Antony, CA Piccirillo, A Akpinarli, SE Finkelstein, PJ Speiss, ...
The Journal of Immunology 174 (5), 2591-2601, 2005
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
M Sukumar, J Liu, Y Ji, M Subramanian, JG Crompton, Z Yu, ...
The Journal of clinical investigation 123 (10), 4479-4488, 2013
TOX is a critical regulator of tumour-specific T cell differentiation
AC Scott, F DŁndar, P Zumbo, SS Chandran, CA Klebanoff, M Shakiba, ...
Nature 571 (7764), 270-274, 2019
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells
CA Klebanoff, SE Finkelstein, DR Surman, MK Lichtman, L Gattinoni, ...
Proceedings of the National Academy of Sciences 101 (7), 1969-1974, 2004
Paths to stemness: building the ultimate antitumour T cell
L Gattinoni, CA Klebanoff, NP Restifo
Nature Reviews Cancer 12 (10), 671-684, 2012
CD8+ T‐cell memory in tumor immunology and immunotherapy
CA Klebanoff, L Gattinoni, NP Restifo
Immunological reviews 211 (1), 214-224, 2006
Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy
CA Klebanoff, HT Khong, PA Antony, DC Palmer, NP Restifo
Trends in immunology 26 (2), 111-117, 2005
Lymphoma remissions caused by anti-CD19 chimeric antigen receptor T cells are associated with high serum interleukin-15 levels
JN Kochenderfer, RPT Somerville, T Lu, V Shi, A Bot, J Rossi, A Xue, ...
Journal of clinical oncology 35 (16), 1803, 2017
Ionic immune suppression within the tumour microenvironment limits T cell effector function
R Eil, SK Vodnala, D Clever, CA Klebanoff, M Sukumar, JH Pan, ...
Nature 537 (7621), 539-543, 2016
IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy
CS Hinrichs, R Spolski, CM Paulos, L Gattinoni, KW Kerstann, DC Palmer, ...
Blood, The Journal of the American Society of Hematology 111 (11), 5326-5333, 2008
Th17 cells are long lived and retain a stem cell-like molecular signature
P Muranski, ZA Borman, SP Kerkar, CA Klebanoff, Y Ji, L Sanchez-Perez, ...
Immunity 35 (6), 972-985, 2011
BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis
R Roychoudhuri, K Hirahara, K Mousavi, D Clever, CA Klebanoff, ...
Nature 498 (7455), 506-510, 2013
Randomized, prospective evaluation comparing intensity of lymphodepletion before adoptive transfer of tumor-infiltrating lymphocytes for patients with metastatic melanoma
SL Goff, ME Dudley, DE Citrin, RP Somerville, JR Wunderlich, ...
Journal of Clinical Oncology 34 (20), 2389, 2016
Therapeutic cancer vaccines: are we there yet?
CA Klebanoff, N Acquavella, Z Yu, NP Restifo
Immunological reviews 239 (1), 27-44, 2011
T cell stemness and dysfunction in tumors are triggered by a common mechanism
SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ...
Science 363 (6434), eaau0135, 2019
The system can't perform the operation now. Try again later.
Articles 1–20