| Tumor mutational load predicts survival after immunotherapy across multiple cancer types RM Samstein, CH Lee, AN Shoushtari, MD Hellmann, R Shen, ... Nature genetics 51 (2), 202-206, 2019 | 2346 | 2019 |
| Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells L Gattinoni, SE Finkelstein, CA Klebanoff, PA Antony, DC Palmer, ... The Journal of experimental medicine 202 (7), 907-912, 2005 | 1123 | 2005 |
| Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells L Gattinoni, CA Klebanoff, DC Palmer, C Wrzesinski, K Kerstann, Z Yu, ... The Journal of clinical investigation 115 (6), 1616-1626, 2005 | 1105 | 2005 |
| Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells CA Klebanoff, L Gattinoni, P Torabi-Parizi, K Kerstann, AR Cardones, ... Proceedings of the national academy of sciences 102 (27), 9571-9576, 2005 | 1089 | 2005 |
| Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells WW Overwijk, MR Theoret, SE Finkelstein, DR Surman, LA De Jong, ... The Journal of experimental medicine 198 (4), 569-580, 2003 | 1079 | 2003 |
| CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells PA Antony, CA Piccirillo, A Akpinarli, SE Finkelstein, PJ Speiss, ... The Journal of Immunology 174 (5), 2591-2601, 2005 | 919 | 2005 |
| Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function M Sukumar, J Liu, Y Ji, M Subramanian, JG Crompton, Z Yu, ... The Journal of clinical investigation 123 (10), 4479-4488, 2013 | 778 | 2013 |
| IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells CA Klebanoff, SE Finkelstein, DR Surman, MK Lichtman, L Gattinoni, ... Proceedings of the National Academy of Sciences 101 (7), 1969-1974, 2004 | 639 | 2004 |
| CD8+ T‐cell memory in tumor immunology and immunotherapy CA Klebanoff, L Gattinoni, NP Restifo Immunological reviews 211 (1), 214-224, 2006 | 601 | 2006 |
| Paths to stemness: building the ultimate antitumour T cell L Gattinoni, CA Klebanoff, NP Restifo Nature Reviews Cancer 12 (10), 671-684, 2012 | 595 | 2012 |
| TOX is a critical regulator of tumour-specific T cell differentiation AC Scott, F Dündar, P Zumbo, SS Chandran, CA Klebanoff, M Shakiba, ... Nature 571 (7764), 270-274, 2019 | 581 | 2019 |
| Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy CA Klebanoff, HT Khong, PA Antony, DC Palmer, NP Restifo Trends in immunology 26 (2), 111-117, 2005 | 509 | 2005 |
| Lymphoma remissions caused by anti-CD19 chimeric antigen receptor T cells are associated with high serum interleukin-15 levels JN Kochenderfer, RPT Somerville, T Lu, V Shi, A Bot, J Rossi, A Xue, ... Journal of clinical oncology 35 (16), 1803, 2017 | 476 | 2017 |
| IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy CS Hinrichs, R Spolski, CM Paulos, L Gattinoni, KW Kerstann, DC Palmer, ... Blood, The Journal of the American Society of Hematology 111 (11), 5326-5333, 2008 | 460 | 2008 |
| Ionic immune suppression within the tumour microenvironment limits T cell effector function R Eil, SK Vodnala, D Clever, CA Klebanoff, M Sukumar, JH Pan, ... Nature 537 (7621), 539-543, 2016 | 459 | 2016 |
| Th17 cells are long lived and retain a stem cell-like molecular signature P Muranski, ZA Borman, SP Kerkar, CA Klebanoff, Y Ji, L Sanchez-Perez, ... Immunity 35 (6), 972-985, 2011 | 444 | 2011 |
| BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis R Roychoudhuri, K Hirahara, K Mousavi, D Clever, CA Klebanoff, ... Nature 498 (7455), 506-510, 2013 | 387 | 2013 |
| Therapeutic cancer vaccines: are we there yet? CA Klebanoff, N Acquavella, Z Yu, NP Restifo Immunological reviews 239 (1), 27-44, 2011 | 360 | 2011 |
| Randomized, prospective evaluation comparing intensity of lymphodepletion before adoptive transfer of tumor-infiltrating lymphocytes for patients with metastatic melanoma SL Goff, ME Dudley, DE Citrin, RP Somerville, JR Wunderlich, ... Journal of Clinical Oncology 34 (20), 2389, 2016 | 352 | 2016 |
| Prospects for gene-engineered T cell immunotherapy for solid cancers CA Klebanoff, SA Rosenberg, NP Restifo Nature medicine 22 (1), 26-36, 2016 | 340 | 2016 |
Nicholas P Restifo, MDCellular Immunotherapy ExplorerVerified email at lyell.com
