Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture Q Zhang, J Sidorenko, B Couvy-Duchesne, RE Marioni, MJ Wright, ... Nature communications 11 (1), 4799, 2020 | 338 | 2020 |
Genetic variation in Aquaporin-4 moderates the relationship between sleep and brain Aβ-amyloid burden SR Rainey-Smith, GN Mazzucchelli, VL Villemagne, BM Brown, T Porter, ... Translational psychiatry 8 (1), 47, 2018 | 111 | 2018 |
Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer’s and other neurodegenerative diseases PR Bharadwaj, KA Bates, T Porter, E Teimouri, G Perry, JW Steele, ... Translational psychiatry 3 (12), e332-e332, 2013 | 89 | 2013 |
Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults SM Laws, S Gaskin, A Woodfield, V Srikanth, D Bruce, PE Fraser, T Porter, ... Scientific reports 7 (1), 9766, 2017 | 78 | 2017 |
Fifteen years of the Australian Imaging, Biomarkers and Lifestyle (AIBL) study: progress and observations from 2,359 older adults spanning the spectrum from cognitive normality … C Fowler, SR Rainey-Smith, S Bird, J Bomke, P Bourgeat, BM Brown, ... Journal of Alzheimer's disease reports 5 (1), 443-468, 2021 | 68 | 2021 |
Plasma cortisol, brain amyloid-β, and cognitive decline in preclinical alzheimer’s disease: a 6-year prospective cohort study RH Pietrzak, SM Laws, YY Lim, SJ Bender, T Porter, J Doecke, D Ames, ... Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 2 (1), 45-52, 2017 | 68 | 2017 |
Chronic stress and A lzheimer's disease: the interplay between the hypothalamic–pituitary–adrenal axis, genetics and microglia A Milligan Armstrong, T Porter, H Quek, A White, J Haynes, C Jackaman, ... Biological Reviews 96 (5), 2209-2228, 2021 | 54 | 2021 |
A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer’s disease and gastrointestinal tract disorders EO Adewuyi, EK O’Brien, DR Nyholt, T Porter, SM Laws Communications Biology 5 (1), 691, 2022 | 47 | 2022 |
Impact of APOE-ε4 carriage on the onset and rates of neocortical Aβ-amyloid deposition SC Burnham, SM Laws, CA Budgeon, V Doré, T Porter, P Bourgeat, ... Neurobiology of aging 95, 46-55, 2020 | 42 | 2020 |
Aβ-related memory decline in APOE ε4 noncarriers: Implications for Alzheimer disease YY Lim, SM Laws, VL Villemagne, RH Pietrzak, T Porter, D Ames, ... Neurology 86 (17), 1635-1642, 2016 | 39 | 2016 |
Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease G Cadby, C Giles, PE Melton, K Huynh, NA Mellett, T Duong, A Nguyen, ... Nature communications 13 (1), 3124, 2022 | 37 | 2022 |
KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden T Porter, SC Burnham, V Doré, G Savage, P Bourgeat, K Begemann, ... Scientific Reports 8 (1), 2034, 2018 | 35 | 2018 |
Utility of an Alzheimer’s disease risk-weighted polygenic risk score for predicting rates of cognitive decline in preclinical Alzheimer’s disease: a prospective longitudinal study T Porter, SC Burnham, L Milicic, G Savage, P Maruff, YY Lim, QX Li, ... Journal of Alzheimer's Disease 66 (3), 1193-1211, 2018 | 31 | 2018 |
BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF YY Lim, S Rainey-Smith, Y Lim, SM Laws, V Gupta, T Porter, P Bourgeat, ... International psychogeriatrics 29 (11), 1825-1834, 2017 | 31 | 2017 |
Klotho allele status is not associated with Aβ and APOE ε4–related cognitive decline in preclinical Alzheimer's disease T Porter, SC Burnham, L Milicic, G Savage, P Maruff, YY Lim, D Ames, ... Neurobiology of aging 76, 162-165, 2019 | 29 | 2019 |
Using imputation to provide harmonized longitudinal measures of cognition across AIBL and ADNI R Shishegar, T Cox, D Rolls, P Bourgeat, V Doré, F Lamb, J Robertson, ... Scientific reports 11 (1), 23788, 2021 | 25 | 2021 |
Cognitive gene risk profile for the prediction of cognitive decline in presymptomatic Alzheimer’s disease T Porter, VL Villemagne, G Savage, L Milicic, YY Lim, P Maruff, ... Personalized Medicine in Psychiatry 7, 14-20, 2018 | 24 | 2018 |
A polygenic risk score derived from episodic memory weighted genetic variants is associated with cognitive decline in preclinical Alzheimer’s disease T Porter, SC Burnham, G Savage, YY Lim, P Maruff, L Milicic, M Peretti, ... Frontiers in aging neuroscience 10, 423, 2018 | 21 | 2018 |
Validation of a priori candidate Alzheimer’s disease SNPs with brain amyloid-beta deposition M Vacher, T Porter, VL Villemagne, L Milicic, M Peretti, C Fowler, ... Scientific reports 9 (1), 17069, 2019 | 17 | 2019 |
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease Y Jiang, X Zhou, HY Wong, L Ouyang, FCF Ip, VMN Chau, SF Lau, W Wu, ... Nature aging 2 (7), 616-634, 2022 | 15 | 2022 |