Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium N Robinson, S McComb, R Mulligan, R Dudani, L Krishnan, S Sad Nature immunology 13 (10), 954-962, 2012 | 473 | 2012 |
T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorptions. Correlation with increased IFN-gamma and TNF and … L Krishnan, LJ Guilbert, TG Wegmann, M Belosevic, TR Mosmann Journal of immunology (Baltimore, Md.: 1950) 156 (2), 653-662, 1996 | 455 | 1996 |
Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 … L Krishnan, LJ Guilbert, AS Russell, TG Wegmann, TR Mosmann, ... Journal of immunology (Baltimore, Md.: 1950) 156 (2), 644-652, 1996 | 397 | 1996 |
Archaeosome vaccine adjuvants induce strong humoral, cell-mediated, and memory responses: comparison to conventional liposomes and alum L Krishnan, CJ Dicaire, GB Patel, GD Sprott Infection and immunity 68 (1), 54-63, 2000 | 207 | 2000 |
cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation S McComb, HH Cheung, RG Korneluk, S Wang, L Krishnan, S Sad Cell Death & Differentiation 19 (11), 1791-1801, 2012 | 171 | 2012 |
Reducing the stimulation of CD8+ T cells during infection with intracellular bacteria promotes differentiation primarily into a central (CD62LhighCD44high) subset H van Faassen, M Saldanha, D Gilbertson, R Dudani, L Krishnan, S Sad The Journal of Immunology 174 (9), 5341-5350, 2005 | 132 | 2005 |
Multiple mechanisms compensate to enhance tumor-protective CD8+ T cell response in the long-term despite poor CD8+ T cell priming initially: comparison between an acute versus … R Dudani, Y Chapdelaine, H Faassen, DK Smith, H Shen, L Krishnan, ... The Journal of Immunology 168 (11), 5737-5745, 2002 | 132 | 2002 |
Introduction to the immune system S McComb, A Thiriot, B Akache, L Krishnan, F Stark Immunoproteomics: methods and protocols, 1-24, 2019 | 127 | 2019 |
Archaeosomes induce long-term CD8+ cytotoxic T cell response to entrapped soluble protein by the exogenous cytosolic pathway, in the absence of CD4+ T cell help L Krishnan, S Sad, GB Patel, GD Sprott The Journal of Immunology 165 (9), 5177-5185, 2000 | 123 | 2000 |
The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo L Krishnan, S Sad, GB Patel, GD Sprott The Journal of Immunology 166 (3), 1885-1893, 2001 | 115 | 2001 |
Archaeosome adjuvants: immunological capabilities and mechanism (s) of action L Krishnan, GD Sprott Vaccine 26 (17), 2043-2055, 2008 | 107 | 2008 |
Delayed expansion and contraction of CD8+ T cell response during infection with virulent Salmonella typhimurium RA Luu, K Gurnani, R Dudani, R Kammara, H van Faassen, JC Sirard, ... The Journal of Immunology 177 (3), 1516-1525, 2006 | 95 | 2006 |
Cytotoxicity and weak CD40 ligand expression of CD8+ type 2 cytotoxic T cells restricts their potential B cell helper activity S Sad, L Krishnan, R Chris Bleackley, D Kägi, H Hengartner, ... European journal of immunology 27 (4), 914-922, 1997 | 95 | 1997 |
Immunization of mice with lipopeptide antigens encapsulated in novel liposomes prepared from the polar lipids of various Archaeobacteria elicits rapid and prolonged specific … JW Conlan, L Krishnan, GE Willick, GB Patel, GD Sprott Vaccine 19 (25-26), 3509-3517, 2001 | 93 | 2001 |
Activation of Dendritic Cells by Liposomes Prepared from Phosphatidylinositol Mannosides from Mycobacterium bovis Bacillus Calmette-Guérin and Adjuvant … GD Sprott, CJ Dicaire, K Gurnani, S Sad, L Krishnan Infection and immunity 72 (9), 5235-5246, 2004 | 85 | 2004 |
Archaeosomes varying in lipid composition differ in receptor-mediated endocytosis and differentially adjuvant immune responses to entrapped antigen GD Sprott, S Sad, LP Fleming, CJ DiCaire, GB Patel, L Krishnan Archaea 1, 151-164, 2003 | 83 | 2003 |
Prolonged antigen presentation, APC-, and CD8+ T cell turnover during mycobacterial infection: comparison with Listeria monocytogenes H van Faassen, R Dudani, L Krishnan, S Sad The Journal of Immunology 172 (6), 3491-3500, 2004 | 80 | 2004 |
Archaeosomes induce enhanced cytotoxic T lymphocyte responses to entrapped soluble protein in the absence of interleukin 12 and protect against tumor challenge L Krishnan, S Sad, GB Patel, GD Sprott Cancer Research 63 (10), 2526-2534, 2003 | 80 | 2003 |
From mice to women: the conundrum of immunity to infection during pregnancy L Krishnan, T Nguyen, S McComb Journal of reproductive immunology 97 (1), 62-73, 2013 | 79 | 2013 |
A structural comparison of the total polar lipids from the human archaea Methanobrevibacter smithii and Methanosphaera stadtmanae and its relevance to the adjuvant activities … GD Sprott, JR Brisson, CJ Dicaire, AK Pelletier, LA Deschatelets, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 1999 | 66 | 1999 |