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Lakshmi Krishnan
Lakshmi Krishnan
Verified email at nrc-cnrc.gc.ca
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Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
N Robinson, S McComb, R Mulligan, R Dudani, L Krishnan, S Sad
Nature immunology 13 (10), 954-962, 2012
4732012
T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorptions. Correlation with increased IFN-gamma and TNF and …
L Krishnan, LJ Guilbert, TG Wegmann, M Belosevic, TR Mosmann
Journal of immunology (Baltimore, Md.: 1950) 156 (2), 653-662, 1996
4551996
Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 …
L Krishnan, LJ Guilbert, AS Russell, TG Wegmann, TR Mosmann, ...
Journal of immunology (Baltimore, Md.: 1950) 156 (2), 644-652, 1996
3971996
Archaeosome vaccine adjuvants induce strong humoral, cell-mediated, and memory responses: comparison to conventional liposomes and alum
L Krishnan, CJ Dicaire, GB Patel, GD Sprott
Infection and immunity 68 (1), 54-63, 2000
2072000
cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation
S McComb, HH Cheung, RG Korneluk, S Wang, L Krishnan, S Sad
Cell Death & Differentiation 19 (11), 1791-1801, 2012
1712012
Reducing the stimulation of CD8+ T cells during infection with intracellular bacteria promotes differentiation primarily into a central (CD62LhighCD44high) subset
H van Faassen, M Saldanha, D Gilbertson, R Dudani, L Krishnan, S Sad
The Journal of Immunology 174 (9), 5341-5350, 2005
1322005
Multiple mechanisms compensate to enhance tumor-protective CD8+ T cell response in the long-term despite poor CD8+ T cell priming initially: comparison between an acute versus …
R Dudani, Y Chapdelaine, H Faassen, DK Smith, H Shen, L Krishnan, ...
The Journal of Immunology 168 (11), 5737-5745, 2002
1322002
Introduction to the immune system
S McComb, A Thiriot, B Akache, L Krishnan, F Stark
Immunoproteomics: methods and protocols, 1-24, 2019
1272019
Archaeosomes induce long-term CD8+ cytotoxic T cell response to entrapped soluble protein by the exogenous cytosolic pathway, in the absence of CD4+ T cell help
L Krishnan, S Sad, GB Patel, GD Sprott
The Journal of Immunology 165 (9), 5177-5185, 2000
1232000
The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo
L Krishnan, S Sad, GB Patel, GD Sprott
The Journal of Immunology 166 (3), 1885-1893, 2001
1152001
Archaeosome adjuvants: immunological capabilities and mechanism (s) of action
L Krishnan, GD Sprott
Vaccine 26 (17), 2043-2055, 2008
1072008
Delayed expansion and contraction of CD8+ T cell response during infection with virulent Salmonella typhimurium
RA Luu, K Gurnani, R Dudani, R Kammara, H van Faassen, JC Sirard, ...
The Journal of Immunology 177 (3), 1516-1525, 2006
952006
Cytotoxicity and weak CD40 ligand expression of CD8+ type 2 cytotoxic T cells restricts their potential B cell helper activity
S Sad, L Krishnan, R Chris Bleackley, D Kägi, H Hengartner, ...
European journal of immunology 27 (4), 914-922, 1997
951997
Immunization of mice with lipopeptide antigens encapsulated in novel liposomes prepared from the polar lipids of various Archaeobacteria elicits rapid and prolonged specific …
JW Conlan, L Krishnan, GE Willick, GB Patel, GD Sprott
Vaccine 19 (25-26), 3509-3517, 2001
932001
Activation of Dendritic Cells by Liposomes Prepared from Phosphatidylinositol Mannosides from Mycobacterium bovis Bacillus Calmette-Guérin and Adjuvant …
GD Sprott, CJ Dicaire, K Gurnani, S Sad, L Krishnan
Infection and immunity 72 (9), 5235-5246, 2004
852004
Archaeosomes varying in lipid composition differ in receptor-mediated endocytosis and differentially adjuvant immune responses to entrapped antigen
GD Sprott, S Sad, LP Fleming, CJ DiCaire, GB Patel, L Krishnan
Archaea 1, 151-164, 2003
832003
Prolonged antigen presentation, APC-, and CD8+ T cell turnover during mycobacterial infection: comparison with Listeria monocytogenes
H van Faassen, R Dudani, L Krishnan, S Sad
The Journal of Immunology 172 (6), 3491-3500, 2004
802004
Archaeosomes induce enhanced cytotoxic T lymphocyte responses to entrapped soluble protein in the absence of interleukin 12 and protect against tumor challenge
L Krishnan, S Sad, GB Patel, GD Sprott
Cancer Research 63 (10), 2526-2534, 2003
802003
From mice to women: the conundrum of immunity to infection during pregnancy
L Krishnan, T Nguyen, S McComb
Journal of reproductive immunology 97 (1), 62-73, 2013
792013
A structural comparison of the total polar lipids from the human archaea Methanobrevibacter smithii and Methanosphaera stadtmanae and its relevance to the adjuvant activities …
GD Sprott, JR Brisson, CJ Dicaire, AK Pelletier, LA Deschatelets, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 1999
661999
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