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Somaia Abdel Karim
Somaia Abdel Karim
Professor (Organic Chemistry) Therapeutic Chemistry Department, National Research Center
Verified email at nrc.sci.eg
Title
Cited by
Cited by
Year
Novel coumarin derivatives with expected biological activity
ZM Nofal, MI El-Zahar, SS Abd El-Karim
Molecules 5 (2), 99-113, 2000
3332000
Design, synthesis, biological evaluation and molecular docking studies of novel benzofuran–pyrazole derivatives as anticancer agents
SS Abd El-Karim, MM Anwar, NA Mohamed, T Nasr, SA Elseginy
Bioorganic chemistry 63, 1-12, 2015
902015
Novel benzimidazole derivatives as expected anticancer agents
ZM Nofal, EA Soliman, SS Abd El-Karim, MI El Zahar, AM Srour, ...
Acta Pol Pharm 68, 519-534, 2011
872011
New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies
SS Abd El-Karim, YM Syam, AM El Kerdawy, TM Abdelghany
Bioorganic chemistry 86, 80-96, 2019
692019
Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity
SS Abd El-Karim, HS Mohamed, MF Abdelhameed, AEGE Amr, ...
Bioorganic chemistry 111, 104827, 2021
622021
Synthesis, antitumor activity and molecular docking study of novel benzofuran-2-yl pyrazole pyrimidine derivatives
MI El-Zahar, SA El-Karim, ME Haiba, MA Khedr
Acta Pol Pharm Drug Res 68, 357-373, 2011
602011
Design, synthesis and anticervical cancer activity of new benzofuran–pyrazol-hydrazono-thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis inducing agents
HAS Abbas, SS Abd El-Karim
Bioorganic chemistry 89, 103035, 2019
552019
Rational design and synthesis of new tetralin-sulfonamide derivatives as potent anti-diabetics and DPP-4 inhibitors: 2D & 3D QSAR, in vivo radiolabeling and bio distribution …
SS Abd El-Karim, MM Anwar, YM Syam, MA Nael, HF Ali, MA Motaleb
Bioorganic chemistry 81, 481-493, 2018
522018
Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors
AM Srour, NS Ahmed, SS Abd El-Karim, MM Anwar, SM El-Hallouty
Bioorganic & Medicinal Chemistry 28 (18), 115657, 2020
442020
A comparative study of the anticancer activity and PARP-1 inhibiting effect of benzofuran–pyrazole scaffold and its nano-sized particles in human breast cancer cells
MM Anwar, SS Abd El-Karim, AH Mahmoud, AEGE Amr, MA Al-Omar
Molecules 24 (13), 2413, 2019
422019
Kinase inhibitory activities and molecular docking of a novel series of anticancer pyrazole derivatives
ES Nossier, SS Abd El-Karim, NM Khalifa, AS El-Sayed, ESI Hassan, ...
Molecules 23 (12), 3074, 2018
412018
Synthesis and cytotoxicity screening of some novel benzofuranoyl-pyrazole derivatives against liver and cervix carcinoma cell lines
MI El-Zahar, A El-Karim, S Somaia, MM Anwar
South African Journal of Chemistry 62, 189-199, 2009
332009
Synthesis and biological evaluation of new derivatives of thieno-thiazole and dihydrothiazolo-thiazole scaffolds integrated with a pyrazoline nucleus as anticancer and multi …
IMM Othman, ZM Alamshany, NY Tashkandi, MAM Gad-Elkareem, ...
RSC advances 12 (1), 561-577, 2022
312022
Synthesis of some new benzimidazole-thiazole derivatives as anticancer agents
TJM ZM Nofal, EA Soliman, SS Abd El-Karim, MI El Zahar, AM Srour, S ...
J Heterocyclic Chemistry 51, 1797-1806, 2014
222014
Synthesis and cytotoxic evalution of some novel 6-(Benzofuran-yl)-4-(4-fluorophenyl) pyridines
HME El-Zahar MI, Abd El-Karim SS
World journal of chemistry 4 (2), 182-194, 2009
22*2009
Synthesis and molecular modeling of new benzimidazoles as glutathione S-transferase inhibitors and anticancer agents
SS Abd El-Karim, MM Anwar, ER Zaki, SA Elseginy, ZM Nofal
Future Medicinal Chemistry 10 (02), 157-181, 2018
202018
Synthesis, antimicrobial and antioxidant activities of some novel cyclized naphthyl cyclohexanone derivatives
MI El-Zahar, SS Abd El-Karim, MM Anwar, EM Danial
Der Pharma Chemica 2 (4), 118-134, 2010
202010
Synthesis and anticancer evaluation of novel isoxazole/pyrazole derivatives
SM Abu Bakr, SS Abd El-Karim, MM Said, MM Youns
Research on Chemical Intermediates 42, 1387-1399, 2016
182016
Anti-Alzheimer activity of new coumarin-based derivatives targeting acetylcholinesterase inhibition
NN Kamel, HF Aly, GI Fouad, SS Abd El-Karim, MM Anwar, YM Syam, ...
RSC advances 13 (27), 18496-18510, 2023
172023
New quinoxaline compounds as DPP-4 inhibitors and hypoglycemics: design, synthesis, computational and bio-distribution studies
YM Syam, MM Anwar, SS Abd El-Karim, SA Elseginy, BM Essa, TM Sakr
RSC advances 11 (58), 36989-37010, 2021
162021
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