Andrea Coletta
Andrea Coletta
Claviate, Aarhus
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Multiple functions of insulin-degrading enzyme: a metabolic crosslight?
GR Tundo, D Sbardella, C Ciaccio, G Grasso, M Gioia, A Coletta, ...
Critical reviews in biochemistry and molecular biology 52 (5), 554-582, 2017
The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
GR Tundo, D Sbardella, AM Santoro, A Coletta, F Oddone, G Grasso, ...
Pharmacology & therapeutics 213, 107579, 2020
Interaction between natural compounds and human topoisomerase I
S Castelli, A Coletta, I D’Annessa, P Fiorani, C Tesauro, A Desideri
Biological Chemistry 393 (11), 1327-1340, 2012
Effect of oxindolimine copper(ii) and zinc(ii) complexes on human topoisomerase I activity
P Katkar, A Coletta, S Castelli, GL Sabino, RAA Couto, ...
Metallomics 6 (1), 117-125, 2014
Structural and dynamical effects induced by the anticancer drug topotecan on the human topoisomerase I–DNA complex
G Mancini, I D'Annessa, A Coletta, N Sanna, G Chillemi, A Desideri
PloS one 5 (6), e10934, 2010
The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S
D Sbardella, GR Tundo, A Coletta, J Marcoux, EI Koufogeorgou, ...
Cellular and molecular life sciences 75, 3441-3456, 2018
Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico
C Tesauro, B Morozzo della Rocca, A Ottaviani, A Coletta, L Zuccaro, ...
Molecular cancer 12, 1-13, 2013
Isoniazid inhibits the heme-based reactivity of Mycobacterium tuberculosis truncated hemoglobin N
P Ascenzi, A Coletta, Y Cao, V Trezza, L Leboffe, G Fanali, M Fasano, ...
PLoS One 8 (8), e69762, 2013
Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein–DNA binding site
I D'Annessa, A Coletta, T Sutthibutpong, J Mitchell, G Chillemi, S Harris, ...
Nucleic acids research 42 (14), 9304-9312, 2014
Cooperativity and allostery in haemoglobin function
C Ciaccio, A Coletta, G De Sanctis, S Marini, M Coletta
IUBMB life 60 (2), 112-123, 2008
Role of the protein in the DNA sequence specificity of the cleavage site stabilized by the camptothecin topoisomerase IB inhibitor: a metadynamics study
A Coletta, A Desideri
Nucleic Acids Research 41 (22), 9977-9986, 2013
Insight into the molecular mechanism behind PEG-mediated stabilization of biofluid lipases
B Pérez, A Coletta, JN Pedersen, SV Petersen, X Periole, JS Pedersen, ...
Scientific Reports 8 (1), 12293, 2018
Binding of an Indenoisoquinoline to the topoisomerase-DNA complex induces reduction of linker mobility and strengthening of protein-DNA interaction
G Mancini, I D’Annessa, A Coletta, G Chillemi, Y Pommier, M Cushman, ...
PLoS One 7 (12), e51354, 2012
Role of hemoglobin structural-functional relationships in oxygen transport
C Ciaccio, A Coletta, M Coletta
Molecular Aspects of Medicine 84, 101022, 2022
Characterization of the differences in the cyclopiazonic acid binding mode to mammalian and P. Falciparum Ca2+ pumps: A computational study
D Di Marino, I D'Annessa, A Coletta, A Via, A Tramontano
Proteins: Structure, Function, and Bioinformatics 83 (3), 564-574, 2015
Molecular Modeling Investigation of the Interaction between Humicola insolens Cutinase and SDS Surfactant Suggests a Mechanism for Enzyme Inactivation
LR Kjølbye, A Laustsen, M Vestergaard, X Periole, L De Maria, ...
Journal of chemical information and modeling 59 (5), 1977-1987, 2019
Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: novel insights into its pro-proteostatic effect
D Sbardella, A Coletta, GR Tundo, IMM Ahmed, F Bellia, F Oddone, ...
Biochemical Pharmacology 177, 113977, 2020
An amber compatible molecular mechanics force field for the anticancer drug topotecan
G Chillemi, A Coletta, G Mancini, N Sanna, A Desideri
Theoretical Chemistry Accounts 127, 293-302, 2010
Solvent Effects on the Valence UV− Vis Absorption Spectra of Topotecan Anticancer Drug in Aqueous Solution at Room Temperature: A Nanoseconds Time-Scale TD-DFT/MD Computational …
C Zazza, A Coletta, N Sanna, G Chillemi, G Mancini, A Desideri
The Journal of Physical Chemistry B 114 (20), 6770-6778, 2010
Mutants and molecular dockings reveal that the primary L-thyroxine binding site in human serum albumin is not the one which can cause familial dysalbuminemic hyperthyroxinemia
U Kragh-Hansen, L Minchiotti, A Coletta, K Bienk, M Galliano, B Schiøtt, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (4), 648-660, 2016
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