| Multiple functions of insulin-degrading enzyme: a metabolic crosslight? GR Tundo, D Sbardella, C Ciaccio, G Grasso, M Gioia, A Coletta, ... Critical reviews in biochemistry and molecular biology 52 (5), 554-582, 2017 | 83 | 2017 |
| The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges GR Tundo, D Sbardella, AM Santoro, A Coletta, F Oddone, G Grasso, ... Pharmacology & therapeutics 213, 107579, 2020 | 58 | 2020 |
| Interaction between natural compounds and human topoisomerase I S Castelli, A Coletta, I D’Annessa, P Fiorani, C Tesauro, A Desideri Biological chemistry 393 (11), 1327-1340, 2012 | 56 | 2012 |
| Effect of oxindolimine copper(ii) and zinc(ii) complexes on human topoisomerase I activity P Katkar, A Coletta, S Castelli, GL Sabino, RAA Couto, ... Metallomics 6 (1), 117-125, 2014 | 46 | 2014 |
| Structural and dynamical effects induced by the anticancer drug topotecan on the human topoisomerase I–DNA complex G Mancini, I D'Annessa, A Coletta, N Sanna, G Chillemi, A Desideri PloS one 5 (6), e10934, 2010 | 45 | 2010 |
| Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico C Tesauro, B Morozzo della Rocca, A Ottaviani, A Coletta, L Zuccaro, ... Molecular cancer 12, 1-13, 2013 | 36 | 2013 |
| The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S D Sbardella, GR Tundo, A Coletta, J Marcoux, EI Koufogeorgou, ... Cellular and Molecular Life Sciences 75, 3441-3456, 2018 | 34 | 2018 |
| Isoniazid inhibits the heme-based reactivity of Mycobacterium tuberculosis truncated hemoglobin N P Ascenzi, A Coletta, Y Cao, V Trezza, L Leboffe, G Fanali, M Fasano, ... PLoS One 8 (8), e69762, 2013 | 32 | 2013 |
| Cooperativity and allostery in haemoglobin function C Ciaccio, A Coletta, G De Sanctis, S Marini, M Coletta IUBMB life 60 (2), 112-123, 2008 | 31 | 2008 |
| Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein–DNA binding site I D'Annessa, A Coletta, T Sutthibutpong, J Mitchell, G Chillemi, S Harris, ... Nucleic acids research 42 (14), 9304-9312, 2014 | 28 | 2014 |
| Role of the protein in the DNA sequence specificity of the cleavage site stabilized by the camptothecin topoisomerase IB inhibitor: a metadynamics study A Coletta, A Desideri Nucleic Acids Research 41 (22), 9977-9986, 2013 | 27 | 2013 |
| Binding of an Indenoisoquinoline to the topoisomerase-DNA complex induces reduction of linker mobility and strengthening of protein-DNA interaction G Mancini, I D’Annessa, A Coletta, G Chillemi, Y Pommier, M Cushman, ... PLoS One 7 (12), e51354, 2012 | 21 | 2012 |
| Insight into the molecular mechanism behind PEG-mediated stabilization of biofluid lipases B Pérez, A Coletta, JN Pedersen, SV Petersen, X Periole, JS Pedersen, ... Scientific Reports 8 (1), 12293, 2018 | 19 | 2018 |
| Characterization of the differences in the cyclopiazonic acid binding mode to mammalian and P. Falciparum Ca2+ pumps: A computational study D Di Marino, I D'Annessa, A Coletta, A Via, A Tramontano Proteins: Structure, Function, and Bioinformatics 83 (3), 564-574, 2015 | 18 | 2015 |
| An amber compatible molecular mechanics force field for the anticancer drug topotecan G Chillemi, A Coletta, G Mancini, N Sanna, A Desideri Theoretical Chemistry Accounts 127, 293-302, 2010 | 16 | 2010 |
| Mutants and molecular dockings reveal that the primary L-thyroxine binding site in human serum albumin is not the one which can cause familial dysalbuminemic hyperthyroxinemia U Kragh-Hansen, L Minchiotti, A Coletta, K Bienk, M Galliano, B Schiøtt, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (4), 648-660, 2016 | 15 | 2016 |
| Molecular Modeling Investigation of the Interaction between Humicola insolens Cutinase and SDS Surfactant Suggests a Mechanism for Enzyme Inactivation LR Kjølbye, A Laustsen, M Vestergaard, X Periole, L De Maria, ... Journal of chemical information and modeling 59 (5), 1977-1987, 2019 | 14 | 2019 |
| Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase I targeting drug: a case study MB Andersen, C Tesauro, M Gonzalez, EL Kristoffersen, C Alonso, ... Nanoscale 9 (5), 1886-1895, 2017 | 14 | 2017 |
| Solvent Effects on the Valence UV− Vis Absorption Spectra of Topotecan Anticancer Drug in Aqueous Solution at Room Temperature: A Nanoseconds Time-Scale TD-DFT/MD Computational … C Zazza, A Coletta, N Sanna, G Chillemi, G Mancini, A Desideri The Journal of Physical Chemistry B 114 (20), 6770-6778, 2010 | 14 | 2010 |
| Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: Novel insights into its pro-proteostatic effect D Sbardella, A Coletta, GR Tundo, IMM Ahmed, F Bellia, F Oddone, ... Biochemical Pharmacology 177, 113977, 2020 | 12 | 2020 |
Giovanni ChillemiDIBAF - University of TusciaVerified email at unitus.it
