Synthesis, biological evaluation and molecular modeling study of new (1, 2, 4-triazole or 1, 3, 4-thiadiazole)-methylthio-derivatives of quinazolin-4 (3H)-one as DHFR inhibitors YI El-Gazzar, HH Georgey, SM El-Messery, HA Ewida, GS Hassan, ... Bioorganic Chemistry 72, 282-292, 2017 | 51 | 2017 |
Diagnostic evaluation of urinary angiogenin (ANG) and clusterin (CLU) as biomarker for bladder cancer MI Shabayek, OM Sayed, HA Attaia, HA Awida, H Abozeed Pathology & Oncology Research 20, 859-866, 2014 | 35 | 2014 |
Thiazolo [4, 5-d] pyridazine analogues as a new class of dihydrofolate reductase (DHFR) inhibitors: Synthesis, biological evaluation and molecular modeling study MA Ewida, DA Abou El Ella, DS Lasheen, HA Ewida, YI El-Gazzar, ... Bioorganic chemistry 74, 228-237, 2017 | 26 | 2017 |
Imidazo [2′, 1′: 2, 3] thiazolo [4, 5-d] pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study MA Ewida, DA Abou El Ella, DS Lasheen, HA Ewida, YI El-Gazzar, ... Bioorganic Chemistry 80, 11-23, 2018 | 25 | 2018 |
Design, synthesis, and biological evaluation of novel amide and hydrazide based thioether analogs targeting Histone deacteylase (HDAC) enzymes AB Farag, HA Ewida, MS Ahmed European journal of medicinal chemistry 148, 73-85, 2018 | 20 | 2018 |
Evaluation and screening of mRNA S100A genes as serological biomarkers in different stages of bladder cancer in Egypt MF Ismail, NA El Boghdady, MI Shabayek, HA Awida, H Abozeed Tumor Biology 37, 4621-4631, 2016 | 19 | 2016 |
Synthesis, antitumor testing and molecular modeling study of some new 6-substituted amido, azo or thioureido-quinazolin-4 (3H)-ones MA Sabry, HA Ewida, GS Hassan, MA Ghaly, HI El-Subbagh Bioorganic Chemistry 88, 102923, 2019 | 17 | 2019 |
MicroRNAs 342 and 450 together with NOX‐4 activity and their association with coronary artery disease in diabetes M Seleem, M Shabayek, HA Ewida Diabetes/Metabolism Research and Reviews 35 (5), e3130, 2019 | 12 | 2019 |
Circulating lncRNAs HIF1A-AS2 and LINLK-A: Role and relation to hypoxia-inducible factor-1α in cerebral stroke patients HA Ewida, RK Zayed, HA Darwish, AA Shaheen Molecular Neurobiology 58 (9), 4564-4574, 2021 | 8 | 2021 |
Promising role of topical caffeine mesoporous gel in collagen resynthesis and UV protection through proline assessment M Seleem, YS Abulfadl, NE Hoffy, NM Lotfy, HA Ewida Future Journal of Pharmaceutical Sciences 8 (1), 27, 2022 | 7 | 2022 |
3-Methyl-imidazo [2, 1-b] thiazole derivatives as a new class of antifolates: Synthesis, in vitro/in vivo bio-evaluation and molecular modeling simulations MA Ewida, HA Ewida, MS Ahmed, HA Allam, RI ElBagary, RF George, ... Bioorganic Chemistry 115, 105205, 2021 | 7 | 2021 |
Nanomolar potency of imidazo[2,1‐b]thiazole analogs as indoleamine 2,3‐dioxygenase inhibitors MA Ewida, HA Ewida, MS Ahmed, HA Allam, RI ElBagary, RF George, ... Archiv der Pharmazie 354 (11), 2100202, 2021 | 4 | 2021 |
Successful stories of drug repurposing for cancer therapy in hepatocellular carcinoma YM Attia, H Ewida, MS Ahmed Drug Repurposing in Cancer Therapy, 213-229, 2020 | 4 | 2020 |
Inhibition of pyruvate dehydrogenase in the heart as an initiating event in the development of diabetic cardiomyopathy A Elnwasany, HA Ewida, PA Szweda, LI Szweda Antioxidants 12 (3), 756, 2023 | 3 | 2023 |
Evaluation of miRNAs 9 and 342 expressions in sera as diagnostic and prognostic biomarkers for breast cancer HA Ewida, M Shabayek, M Seleem Breast Disease 40 (4), 241-250, 2021 | 1 | 2021 |
Antiproliferative and apoptotic activities of tomato bioactive metabolite on MDA-MB-435 cell line: in silico molecular modeling and molecular dynamics investigation YA Elkhawas, MA Ewida, HA Ewida, M Gonaid, N Khalil Future Journal of Pharmaceutical Sciences 9 (1), 87, 2023 | | 2023 |
Altered Lnc-EGFR, SNHG1, and LincRNA-Cox2 Profiles in Patients with Relapsing-Remitting Multiple Sclerosis: Impact on Disease Activity and Progression MS Attia, HA Ewida, MA Abdel Hafez, SA El-Maraghy, MM El-Sawalhi Diagnostics 13 (8), 1448, 2023 | | 2023 |
Successful Stories of Drug Repurposing for Cancer Therapy in Hepatocellular Carcinoma, To and Cho_Drug Repurposing in Cancer Therapy YM Attia, H Ewida, M Ahmed | | 2020 |
Dihydrofolate reductase (DHFR) inhibition and molecular modeling study of some 6-bromo- or 6,8-dibromo-quinazolin-4(3H)-ones HIES Abdelfattah A. Abdelkhalek, Heba A. Ewida, Shahenda M. El-Messery ... AMERICAN JOURNAL OF PHYSIOLOGY, BIOCHEMISTRY AND PHARMACOLOGY 7 (1), 1-10, 2018 | | 2018 |
Antioxidants Reveal Protection against the Biochemical Changes in Liver, Kidney and Blood Profiles after Clindamycin/Ibuprofen Administration in Dental Patients GK Helal, MI Shabayek, HA El-Ramly, HA Awida International Journal of Pharmacological and Pharmaceutical Sciences 8 (9 …, 2014 | | 2014 |