Follow
Richard Mead
Title
Cited by
Cited by
Year
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target
SC Barber, RJ Mead, PJ Shaw
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (11-12 …, 2006
5752006
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases
MA Myszczynska, PN Ojamies, AMB Lacoste, D Neil, A Saffari, R Mead, ...
Nature Reviews Neurology 16 (8), 440-456, 2020
3702020
Guidelines for preclinical animal research in ALS/MND: A consensus meeting
AC Ludolph, C Bendotti, E Blaugrund, A Chio, L Greensmith, JP Loeffler, ...
Amyotrophic Lateral Sclerosis 11 (1-2), 38-45, 2010
3292010
Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy
CF Valori, K Ning, M Wyles, RJ Mead, AJ Grierson, PJ Shaw, M Azzouz
Science translational medicine 2 (35), 35ra42-35ra42, 2010
3272010
The membrane attack complex of complement causes severe demyelination associated with acute axonal injury
RJ Mead, SK Singhrao, JW Neal, H Lassmann, BP Morgan
The Journal of Immunology 168 (1), 458-465, 2002
2422002
TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD
MA White, E Kim, A Duffy, R Adalbert, BU Phillips, OM Peters, ...
Nature neuroscience 21 (4), 552-563, 2018
2222018
An in vitro screening cascade to identify neuroprotective antioxidants in ALS
SC Barber, A Higginbottom, RJ Mead, S Barber, PJ Shaw
Free Radical Biology and Medicine 46 (8), 1127-1138, 2009
1042009
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
RJ Mead, N Shan, HJ Reiser, F Marshall, PJ Shaw
Nature Reviews Drug Discovery 22 (3), 185-212, 2023
1032023
Optimised and Rapid Pre-clinical Screening in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)
RJ Mead, EJ Bennett, AJ Kennerley, P Sharp, C Sunyach, P Kasher, ...
PloS one 6 (8), e23244, 2011
1032011
Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis
RJ Mead, JW Neal, MR Griffiths, C Linington, M Botto, H Lassmann, ...
Laboratory investigation 84 (1), 21-28, 2004
1002004
Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen
CA Wood-Allum, SC Barber, J Kirby, P Heath, H Holden, R Mead, ...
Brain 129 (7), 1693-1709, 2006
762006
Mannose-binding lectin alleles in a prospectively recruited UK population
R Mead, D Jack, M Pembrey, L Tyfield, M Turner
The Lancet 349 (9066), 1669-1670, 1997
721997
Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss
MA White, Z Lin, E Kim, CM Henstridge, E Pena Altamira, CK Hunt, ...
Acta neuropathologica communications 7, 1-16, 2019
672019
S [+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis
RJ Mead, A Higginbottom, SP Allen, J Kirby, E Bennett, SC Barber, ...
Free Radical Biology and Medicine 61, 438-452, 2013
672013
Advances, challenges and future directions for stem cell therapy in amyotrophic lateral sclerosis
Y Ciervo, K Ning, X Jun, PJ Shaw, RJ Mead
Molecular neurodegeneration 12, 1-22, 2017
622017
Molecular cloning, expression and characterization of the rat analogue of human membrane cofactor protein (MCP/CD46)
R Mead, SJ Hinchliffe, BP Morgan
Immunology 98 (1), 137-143, 1999
561999
Early Detection of Motor Dysfunction in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Using Home Cage Running Wheels
EJ Bennett, RJ Mead, M Azzouz, PJ Shaw, AJ Grierson
PLoS One 9 (9), e107918, 2014
242014
NRF2 as a therapeutic opportunity to impact in the molecular roadmap of ALS
J Jiménez-Villegas, L Ferraiuolo, RJ Mead, PJ Shaw, A Cuadrado, ...
Free Radical Biology and Medicine 173, 125-141, 2021
212021
Method for the treatment of multiple sclerosis by inhibiting IL-17 activity
MI Christie, RJ Mead, SE Rapecki, MK Robinson
US Patent 7,931,900, 2011
19*2011
Extensive phenotypic characterisation of a human TDP-43Q331K transgenic mouse model of amyotrophic lateral sclerosis (ALS)
JA Watkins, JJP Alix, PJ Shaw, RJ Mead
Scientific Reports 11 (1), 16659, 2021
182021
The system can't perform the operation now. Try again later.
Articles 1–20