| structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium Tuberculosis. Bioorg. Med, Chem., 15, 4552 – 4576 MHRI El-Hamamsy, AW Smith, AS Thompson, MD Threadgill | 71* | 2007 |
| Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach HO Tawfik, A Petreni, CT Supuran, MH El-Hamamsy European journal of medicinal chemistry 232, 114190, 2022 | 33 | 2022 |
| 1,4-Dihydropyridine Calcium Channel Blockers: Homology Modeling of the Receptor and Assessment of Structure Activity Relationship TFEM Moataz A. Shaldam, Mervat H. Elhamamsy, Eman A. Esmat ISRN Medicinal Chemistry 2014, 14, 2014 | 28* | 2014 |
| Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors HO Tawfik, TF El-Moselhy, NS El-Din, MH El-Hamamsy Bioorganic & Medicinal Chemistry 27 (23), 115126, 2019 | 22 | 2019 |
| Synthesis, evaluation and docking study of 1, 3, 5-triazine derivatives as cytotoxic agents against lung cancer MF Balahaa, MH El-Hamamsyb, NAS El-Dinc, NA El-Mahdyd Journal of Applied Pharmaceutical Science 6 (4), 028-045, 2016 | 22 | 2016 |
| Design, synthesis, and molecular docking study of new monastrol analogues as kinesin spindle protein inhibitors MH El‐Hamamsy, NA Sharafeldin, TF El‐Moselhy, HO Tawfik Archiv der Pharmazie 353 (8), 2000060, 2020 | 15 | 2020 |
| Dependence on linkers’ flexibility designed for benzenesulfonamides targeting discovery of novel hCA IX inhibitors as potent anticancer agents HO Tawfik, A Belal, MAS Abourehab, A Angeli, A Bonardi, CT Supuran, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2765-2785, 2022 | 13 | 2022 |
| Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX AI Zain-Alabdeen, TF El-Moselhy, N Sharafeldin, A Angeli, CT Supuran, ... Scientific Reports 12 (1), 16756, 2022 | 12 | 2022 |
| New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small … HO Tawfik, AA El-Hamaky, EA El-Bastawissy, KA Shcherbakov, ... Pharmaceuticals 15 (4), 481, 2022 | 12 | 2022 |
| Synthesis, evaluation of pharmacological activity, and molecular docking of 1, 4-dihydropyridines as calcium antagonists MA Shaldam, MH El-Hamamsy, DO Saleh, TF El-Moselhy Chemical and Pharmaceutical Bulletin 64 (4), 297-304, 2016 | 7 | 2016 |
| Discovery of new symmetrical and asymmetrical nitrile-containing 1,4-dihydropyridine derivatives as dual kinases and P-glycoprotein inhibitors: synthesis, in vitro assays, and … MH Saad, TF El-Moselhy, N S, El-Din, ABM Mehany, A Belal, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2489-2511, 2022 | 6 | 2022 |
| Discovery of novel enasidenib analogues targeting inhibition of mutant isocitrate dehydrogenase 2 as antileukaemic agents AF Khalil, TF El-Moselhy, EA El-Bastawissy, R Abdelhady, NS Younis, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2157411, 2023 | 5 | 2023 |
| Accessing the anti-proliferating activity of tankyrase-2 inhibitors via 2d, 3d-QSAR and molecular docking: assessment of structure activity relationships MH El-Hamamsy Journal of Applied Pharmaceutical Science 7 (12), 014-027, 2017 | 4 | 2017 |
| Factorial analysis optimization of memantine hydrochloride spectrofluorimetric quantitation via derivatization withoff-phthalaldehyde in the absence of thiol MH El-Hamamsy Journal of Innovations in Pharmaceutical and Biological Science4 (4), 176-184, 2017 | 4 | 2017 |
| El-Din, NAESS Exploring the cytotoxicity of 1, 3, 5-triazines and triazine analogs against lung cancer by QSAR study using genetic function approximation MF Balaha, MH El-Hamamsy Pharma Chem 8 (3), 180-188, 2016 | 4 | 2016 |
| Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFRWT, EGFRT790M, and EGFRL858R) MG Abo Al-Hamd, HO Tawfik, O Abdullah, K Yamaguchi, M Sugiura, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2241674, 2023 | 3 | 2023 |
| Corrigendum to" Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors"[Bioorg. Med. Chem. 27 (2019) 115126]. HO Tawfik, TF El-Moselhy, NS El-Din, MH El-Hamamsy Bioorganic & medicinal chemistry 28 (2), 115255-115255, 2019 | 1 | 2019 |
| Design, synthesis and biological evaluation of 1, 3, 5-triazine derivatives as potential inhibitors of dihydrofolate reductase M El-Hamamsy, N El-Mahdy Life Sci J 11 (11), 2014 | 1 | 2014 |
| Potential antimycobacterial agent targeting dihydrofolate reductase MHRI El-Hamamsy PQDT-UK & Ireland, 2005 | 1 | 2005 |
| Design and synthesis of quinazolin-4-one derivatives as potential anticancer agents and investigation of their interaction with RecQ helicases HS Haggag, SM Aboukhatwa, MS Nafie, A Paul, N Sharafeldin, AW Oliver, ... Bioorganic Chemistry 144, 107086, 2024 | | 2024 |
