متابعة
Dennie T. Frederick
Dennie T. Frederick
Massachusetts General Hospital
بريد إلكتروني تم التحقق منه على mgh.harvard.edu
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ...
Science 352 (6282), 189-196, 2016
38582016
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
R Straussman, T Morikawa, K Shee, M Barzily-Rokni, ZR Qian, J Du, ...
Nature 487 (7408), 500-504, 2012
19532012
Defining T cell states associated with response to checkpoint immunotherapy in melanoma
M Sade-Feldman, K Yizhak, SL Bjorgaard, JP Ray, CG de Boer, ...
Cell 175 (4), 998-1013. e20, 2018
13712018
Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
LT Geller, M Barzily-Rokni, T Danino, OH Jonas, N Shental, D Nejman, ...
Science 357 (6356), 1156-1160, 2017
13132017
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
10222018
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma
DT Frederick, A Piris, AP Cogdill, ZA Cooper, C Lezcano, CR Ferrone, ...
Clinical cancer research 19 (5), 1225-1231, 2013
9912013
Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF
R Haq, J Shoag, P Andreu-Perez, S Yokoyama, H Edelman, GC Rowe, ...
Cancer cell 23 (3), 302-315, 2013
8432013
Resistance to checkpoint blockade therapy through inactivation of antigen presentation
M Sade-Feldman, YJ Jiao, JH Chen, MS Rooney, M Barzily-Rokni, ...
Nature communications 8 (1), 1136, 2017
8082017
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma
N Auslander, G Zhang, JS Lee, DT Frederick, B Miao, T Moll, T Tian, ...
Nature medicine 24 (10), 1545-1549, 2018
5762018
Toward minimal residual disease-directed therapy in melanoma
F Rambow, A Rogiers, O Marin-Bejar, S Aibar, J Femel, M Dewaele, ...
Cell 174 (4), 843-855. e19, 2018
5732018
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors
DJ Konieczkowski, CM Johannessen, O Abudayyeh, JW Kim, ZA Cooper, ...
Cancer discovery 4 (7), 816-827, 2014
5412014
The Hippo effector YAP promotes resistance to RAF-and MEK-targeted cancer therapies
L Lin, AJ Sabnis, E Chan, V Olivas, L Cade, E Pazarentzos, S Asthana, ...
Nature genetics 47 (3), 250-256, 2015
5302015
MAP Kinase Pathway Alterations in BRAF-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition
N Wagle, EM Van Allen, DJ Treacy, DT Frederick, ZA Cooper, ...
Cancer discovery 4 (1), 61-68, 2014
5272014
Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy
DB Johnson, MV Estrada, R Salgado, V Sanchez, DB Doxie, SR Opalenik, ...
Nature communications 7 (1), 10582, 2016
5112016
A melanocyte lineage program confers resistance to MAP kinase pathway inhibition
CM Johannessen, LA Johnson, F Piccioni, A Townes, DT Frederick, ...
Nature 504 (7478), 138-142, 2013
4832013
Targeted next generation sequencing identifies markers of response to PD-1 blockade
DB Johnson, GM Frampton, MJ Rioth, E Yusko, Y Xu, X Guo, RC Ennis, ...
Cancer immunology research 4 (11), 959-967, 2016
4722016
Intratumoral activity of the CXCR3 chemokine system is required for the efficacy of anti-PD-1 therapy
MT Chow, AJ Ozga, RL Servis, DT Frederick, JA Lo, DE Fisher, ...
Immunity 50 (6), 1498-1512. e5, 2019
4692019
BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice
C Liu, W Peng, C Xu, Y Lou, M Zhang, JA Wargo, JQ Chen, HS Li, ...
Clinical cancer research 19 (2), 393-403, 2013
4012013
sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
A Kaur, MR Webster, K Marchbank, R Behera, A Ndoye, CH Kugel, ...
Nature 532 (7598), 250-254, 2016
3552016
Oncogenic BRAF (V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma
JS Khalili, S Liu, TG Rodríguez-Cruz, M Whittington, S Wardell, C Liu, ...
Clinical Cancer Research 18 (19), 5329-5340, 2012
3252012
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مقالات 1–20