| CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase W He, G Bai, H Zhou, N Wei, NM White, J Lauer, H Liu, Y Shi, CD Dumitru, ... Nature 526 (7575), 710-714, 2015 | 156 | 2015 |
| Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy Z Mo, X Zhao, H Liu, Q Hu, XQ Chen, J Pham, NA Wei, ZE Liu, J Zhou, ... Nature communications 9 (1), 1007, 2018 | 100 | 2018 |
| Neurodegenerative Charcot–Marie–Tooth disease as a case study to decipher novel functions of aminoacyl-tRNA synthetases N Wei, Q Zhang, XL Yang Journal of Biological Chemistry 294 (14), 5321-5339, 2019 | 78 | 2019 |
| Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage N Wei, Y Shi, LN Truong, KM Fisch, T Xu, E Gardiner, G Fu, YSO Hsu, ... Molecular cell 56 (2), 323-332, 2014 | 73 | 2014 |
| Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations JN Sleigh, JM Dawes, SJ West, N Wei, EL Spaulding, A Gómez-Martín, ... Proceedings of the National Academy of Sciences 114 (16), E3324-E3333, 2017 | 70 | 2017 |
| Allele-specific RNA interference prevents neuropathy in Charcot-Marie-Tooth disease type 2D mouse models KH Morelli, LB Griffin, NK Pyne, LM Wallace, AM Fowler, SN Oprescu, ... The Journal of clinical investigation 129 (12), 5568-5583, 2019 | 53 | 2019 |
| Cancer targeting Gene-Viro-Therapy of liver carcinoma by dual-regulated oncolytic adenovirus armed with TRAIL gene X Cao, M Yang, RC Wei, Y Zeng, JF Gu, WD Huang, DQ Yang, HL Li, ... Gene therapy 18 (8), 765-777, 2011 | 48 | 2011 |
| Targeting gene‐virotherapy for prostate cancer by dd3‐driven oncolytic virus‐harboring interleukin‐24 gene JK Fan, N Wei, M Ding, JF Gu, XR Liu, BH Li, R Qi, WD Huang, YH Li, ... International journal of cancer 127 (3), 707-717, 2010 | 46 | 2010 |
| Significant antitumor activity of oncolytic adenovirus expressing human interferon‐β for hepatocellular carcinoma LF He, JF Gu, WH Tang, JK Fan, N Wei, WG Zou, YH Zhang, LL Zhao, ... The Journal of Gene Medicine 10 (9), 983-992, 2008 | 45 | 2008 |
| Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy D Blocquel, S Li, N Wei, H Daub, M Sajish, ML Erfurth, G Kooi, J Zhou, ... Nucleic acids research 45 (13), 8091-8104, 2017 | 44 | 2017 |
| tRNA-controlled Nuclear Import of a Human tRNA Synthetase*♦ G Fu, T Xu, Y Shi, N Wei, XL Yang Journal of Biological Chemistry 287 (12), 9330-9334, 2012 | 44 | 2012 |
| HCCS1-armed, quadruple-regulated oncolytic adenovirus specific for liver cancer as a cancer targeting gene-viro-therapy strategy HN Xu, WD Huang, Y Cai, M Ding, JF Gu, N Wei, LY Sun, X Cao, HG Li, ... Molecular cancer 10, 1-14, 2011 | 38 | 2011 |
| Complete eradication of hepatomas using an oncolytic adenovirus containing AFP promoter controlling E1A and an E1B deletion to drive IL-24 expression KJ Zhang, J Zhang, YM Wu, J Qian, XJ Liu, LC Yan, XM Zhou, RJ Xiao, ... Cancer gene therapy 19 (9), 619-629, 2012 | 30 | 2012 |
| Transcriptional dysregulation by a nucleus-localized aminoacyl-tRNA synthetase associated with Charcot-Marie-Tooth neuropathy S Bervoets, N Wei, ML Erfurth, S Yusein-Myashkova, B Ermanoska, ... Nature communications 10 (1), 5045, 2019 | 27 | 2019 |
| CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells D Blocquel, L Sun, Z Matuszek, S Li, T Weber, B Kuhle, G Kooi, N Wei, ... Proceedings of the National Academy of Sciences 116 (39), 19440-19448, 2019 | 27 | 2019 |
| Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis JN Sleigh, A Gómez-Martín, N Wei, G Bai, XL Yang, G Schiavo Scientific Reports 7 (1), 9216, 2017 | 24 | 2017 |
| Double-regulated oncolytic adenovirus-mediated interleukin-24 overexpression exhibits potent antitumor activity on gastric adenocarcinoma N Wei, JK Fan, JF Gu, XY Liu Human gene therapy 21 (7), 855-864, 2010 | 22 | 2010 |
| Increased suppression of oncolytic adenovirus carrying mutant k5 on colorectal tumor JK Fan, T Xiao, JF Gu, N Wei, LF He, M Ding, XY Liu Biochemical and biophysical research communications 374 (2), 198-203, 2008 | 21 | 2008 |
| CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS L Sun, N Wei, B Kuhle, D Blocquel, S Novick, Z Matuszek, H Zhou, W He, ... Proceedings of the National Academy of Sciences 118 (13), e2012898118, 2021 | 17 | 2021 |
| A double-regulated oncolytic adenovirus with improved safety for adenocarcinoma therapy N Wei, JK Fan, JF Gu, LF He, WH Tang, X Cao, XY Liu Biochemical and biophysical research communications 388 (2), 234-239, 2009 | 16 | 2009 |
