Penicillin binding protein 2a: An overview and a medicinal chemistry perspective MAW Shalaby, EME Dokla, RAT Serya, KAM Abouzid European journal of medicinal chemistry 199, 112312, 2020 | 84 | 2020 |
Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria EME Dokla, NS Abutaleb, SN Milik, D Li, K El-Baz, MAW Shalaby, ... European Journal of Medicinal Chemistry 186, 111850, 2020 | 54 | 2020 |
1, 2, 4-Oxadiazole derivatives targeting EGFR and c-Met degradation in TKI resistant NSCLC EME Dokla, CS Fang, KAM Abouzid, CS Chen European Journal of Medicinal Chemistry 182, 111607, 2019 | 30 | 2019 |
SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria EME Dokla, NS Abutaleb, SN Milik, EAEA Kandil, OM Qassem, ... European Journal of Medicinal Chemistry 247, 115040, 2023 | 10 | 2023 |
Discovery of a benzimidazole-based dual FLT3/TrKA inhibitor targeting acute myeloid leukemia EME Dokla, AK Abdel-Aziz, SN Milik, MJ McPhillie, S Minucci, ... Bioorganic & Medicinal Chemistry 56, 116596, 2022 | 10 | 2022 |
Applying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea … EM Dokla, AH Mahmoud, MSA Elsayed, AH El-Khatib, MW Linscheid, ... Plos one 7 (11), e49284, 2012 | 10 | 2012 |
A 5′ AMP‐activated protein kinase enzyme activator, compound 59, induces autophagy and apoptosis in human oral squamous cell carcinoma JR Weng, EME Dokla, LY Bai, CS Chen, SJ Chiu, TM Shieh Basic & Clinical Pharmacology & Toxicology 123 (1), 21-29, 2018 | 9 | 2018 |
Targeting YAP degradation by a novel 1, 2, 4-oxadiazole derivative via restoration of the function of the Hippo pathway EME Dokla, CS Fang, PC Chu, CS Chang, KAM Abouzid, CS Chen ACS Medicinal Chemistry Letters 11 (4), 426-432, 2020 | 7 | 2020 |
Identification of novel pyrazole and benzimidazole based derivatives as PBP2a inhibitors: Design, synthesis, and biological evaluation MAW Shalaby, EME Dokla, RAT Serya, KAM Abouzid Archives of Pharmaceutical Sciences Ain Shams University 3 (2), 228-245, 2019 | 7 | 2019 |
Indolin-2-one derivatives as selective Aurora B kinase inhibitors targeting breast cancer EME Dokla, AK Abdel-Aziz, SN Milik, AH Mahmoud, MK Saadeldin, ... Bioorganic Chemistry 117, 105451, 2021 | 6 | 2021 |
Discovery of EMD37, a 1, 2, 4-oxadiazole derivative, as a novel endoplasmic reticulum stress inducer with potent anticancer activity AK Abdel-Aziz, EME Dokla, KAM Abouzid, S Minucci Biochemical Pharmacology 206, 115316, 2022 | 5 | 2022 |
Development of potent adenosine monophosphate activated protein kinase (AMPK) activators EME Dokla, CS Fang, PT Lai, SK Kulp, RAT Serya, NSM Ismail, ... ChemMedChem 10 (11), 1915-1923, 2015 | 4 | 2015 |
FLT3 inhibitors and novel therapeutic strategies to reverse AML resistance: an updated comprehensive review AK Abdel-Aziz, EME Dokla, MK Saadeldin Critical Reviews in Oncology/Hematology, 104139, 2023 | 3 | 2023 |
Induction of apoptosis using ATN as a novel Yes‐associated protein inhibitor in human oral squamous cell carcinoma cells PC Chu, EME Dokla, JL Hu, JR Weng Environmental Toxicology 37 (6), 1404-1412, 2022 | 3 | 2022 |
Ligand design, synthesis and biological anti-HCV evaluations for genotypes 1b and 4a of certain 4-(3-& 4-[3-(3, 5-dibromo-4-hydroxyphenyl)-propylamino] phenyl) butyric acids … MAH Ismail, KAM Abouzid, NS Mohamed, EME Dokla Journal of Enzyme Inhibition and Medicinal Chemistry 28 (6), 1274-1290, 2013 | 3 | 2013 |
Novel sulfonamide-indolinone hybrids targeting mitochondrial respiration of breast cancer cells SWA Helmy, AK Abdel-Aziz, EME Dokla, TE Ahmed, Y Hatem, ... European Journal of Medicinal Chemistry, 116255, 2024 | | 2024 |
Nanoemulgel formulation of a benzimidazole derivative for wound healing EME Dokla, RI El-Gogary, NM Abd-Elsaid, M Gad, RK Abd-Elhalim, ... Journal of Drug Delivery Science and Technology 90, 105121, 2023 | | 2023 |
AML and FLT3: An update on FDA-approved or under review kinase inhibitors targeting FLT3 kinase N Alaa El-Deen, EME Dokla, MY Jaballah, K Abouzid, RA Serya Egyptian Journal of Chemistry, 2023 | | 2023 |
A 5′ AMP-Activated Protein Kinase Enzyme Activator, Compound 59, Induces Autophagy and Apoptosis in Human Oral JR Weng, EME Dokla, LY Bai, CS Chen, SJ Chiu, TM Shieh of BCPT (former Nordic Pharmacological Society) and Editors of the products …, 1865 | | 1865 |