متابعة
Patrick Hwu
Patrick Hwu
President and CEO, The Moffitt Cancer Center, Tampa, FL
بريد إلكتروني تم التحقق منه على moffitt.org
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
Safety and activity of anti–PD-L1 antibody in patients with advanced cancer
JR Brahmer, SS Tykodi, LQM Chow, WJ Hwu, SL Topalian, P Hwu, ...
New England Journal of Medicine 366 (26), 2455-2465, 2012
87782012
Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
V Gopalakrishnan, CN Spencer, L Nezi, A Reuben, MC Andrews, ...
Science 359 (6371), 97-103, 2018
38442018
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
ME Dudley, JR Wunderlich, PF Robbins, JC Yang, P Hwu, ...
Science 298 (5594), 850-854, 2002
37332002
A randomized trial of bevacizumab, an anti–vascular endothelial growth factor antibody, for metastatic renal cancer
JC Yang, L Haworth, RM Sherry, P Hwu, DJ Schwartzentruber, ...
New England Journal of Medicine 349 (5), 427-434, 2003
35772003
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
SA Rosenberg, JC Yang, DJ Schwartzentruber, P Hwu, FM Marincola, ...
Nature medicine 4 (3), 321-327, 1998
22371998
Chimeric antigen receptor T-cell therapy—assessment and management of toxicities
SS Neelapu, S Tummala, P Kebriaei, W Wierda, C Gutierrez, FL Locke, ...
Nature reviews Clinical oncology 15 (1), 47-62, 2018
20722018
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
GQ Phan, JC Yang, RM Sherry, P Hwu, SL Topalian, ...
Proceedings of the National Academy of Sciences 100 (14), 8372-8377, 2003
19342003
B cells and tertiary lymphoid structures promote immunotherapy response
BA Helmink, SM Reddy, J Gao, S Zhang, R Basar, R Thakur, K Yizhak, ...
Nature 577 (7791), 549-555, 2020
16812020
A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
MH Kershaw, JA Westwood, LL Parker, G Wang, Z Eshhar, ...
Clinical cancer research 12 (20), 6106-6115, 2006
14622006
Loss of PTEN promotes resistance to T cell–mediated immunotherapy
W Peng, JQ Chen, C Liu, S Malu, C Creasy, MT Tetzlaff, C Xu, ...
Cancer discovery 6 (2), 202-216, 2016
13712016
PD-L1 expression in triple-negative breast cancer
EA Mittendorf, AV Philips, F Meric-Bernstam, N Qiao, Y Wu, S Harrington, ...
Cancer immunology research 2 (4), 361-370, 2014
13092014
Loss of IFN-γ pathway genes in tumor cells as a mechanism of resistance to anti-CTLA-4 therapy
J Gao, LZ Shi, H Zhao, J Chen, L Xiong, Q He, T Chen, J Roszik, ...
Cell 167 (2), 397-404. e9, 2016
11972016
gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
DJ Schwartzentruber, DH Lawson, JM Richards, RM Conry, DM Miller, ...
New England Journal of Medicine 364 (22), 2119-2127, 2011
10862011
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
10212018
Randomized study of high-dose and low-dose inter leukin-2 in patients with metastatic renal cancer
JC Yang, RM Sherry, SM Steinberg, SL Topalian, DJ Schwartzentruber, ...
Journal of clinical oncology: official journal of the American Society of …, 2003
10082003
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma
DT Frederick, A Piris, AP Cogdill, ZA Cooper, C Lezcano, CR Ferrone, ...
Clinical cancer research 19 (5), 1225-1231, 2013
9912013
Indoleamine 2, 3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation
P Hwu, MX Du, R Lapointe, M Do, MW Taylor, HA Young
The Journal of Immunology 164 (7), 3596-3599, 2000
9522000
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
N Martin-Orozco, P Muranski, Y Chung, XO Yang, T Yamazaki, S Lu, ...
Immunity 31 (5), 787-798, 2009
9492009
Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade
PL Chen, W Roh, A Reuben, ZA Cooper, CN Spencer, PA Prieto, JP Miller, ...
Cancer discovery 6 (8), 827-837, 2016
9262016
Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma
JF Toso, VJ Gill, P Hwu, FM Marincola, NP Restifo, DJ Schwartzentruber, ...
Journal of clinical oncology: official journal of the American Society of …, 2002
8392002
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مقالات 1–20