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S. Halene
S. Halene
Verified email at yale.edu
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Year
Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study
G Goshua, AB Pine, ML Meizlish, CH Chang, H Zhang, P Bahel, A Baluha, ...
The Lancet Haematology 7 (8), e575-e582, 2020
11052020
Development and function of human innate immune cells in a humanized mouse model
A Rongvaux, T Willinger, J Martinek, T Strowig, SV Gearty, LL Teichmann, ...
Nature biotechnology 32 (4), 364-372, 2014
7782014
SRSF2 mutations contribute to myelodysplasia by mutant-specific effects on exon recognition
E Kim, JO Ilagan, Y Liang, GM Daubner, SCW Lee, A Ramakrishnan, Y Li, ...
Cancer cell 27 (5), 617-630, 2015
5972015
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity
PL Sulkowski, CD Corso, ND Robinson, SE Scanlon, KR Purshouse, ...
Science translational medicine 9 (375), eaal2463, 2017
5052017
High-spatial-resolution multi-omics sequencing via deterministic barcoding in tissue
Y Liu, M Yang, Y Deng, G Su, A Enninful, CC Guo, T Tebaldi, D Zhang, ...
Cell 183 (6), 1665-1681. e18, 2020
4782020
Immune response to green fluorescent protein: implications for gene therapy
R Stripecke, M del Carmen Villacres, DC Skelton, N Satake, S Halene, ...
Gene therapy 6 (7), 1305-1312, 1999
4131999
Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation
SX Gu, T Tyagi, K Jain, VW Gu, SH Lee, JM Hwa, JM Kwan, DS Krause, ...
Nature Reviews Cardiology 18 (3), 194-209, 2021
3952021
Inflammasome activation in infected macrophages drives COVID-19 pathology
E Sefik, R Qu, C Junqueira, E Kaffe, H Mirza, J Zhao, JR Brewer, A Han, ...
Nature 606 (7914), 585-593, 2022
3372022
A neutrophil activation signature predicts critical illness and mortality in COVID-19
ML Meizlish, AB Pine, JD Bishai, G Goshua, ER Nadelmann, M Simonov, ...
Blood advances 5 (5), 1164-1177, 2021
2862021
Pediatric non–Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes
JDE De Rooij, C Branstetter, J Ma, Y Li, MP Walsh, J Cheng, A Obulkasim, ...
Nature genetics 49 (3), 451-456, 2017
1872017
Improved expression in hematopoietic and lymphoid cells in mice after transplantation of bone marrow transduced with a modified retroviral vector
S Halene, L Wang, RM Cooper, DC Bockstoce, PB Robbins, DB Kohn
Blood, The Journal of the American Society of Hematology 94 (10), 3349-3357, 1999
1811999
Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells
PB Robbins, DC Skelton, XJ Yu, S Halene, EH Leonard, DB Kohn
Proceedings of the National Academy of Sciences 95 (17), 10182-10187, 1998
1761998
Circulating markers of angiogenesis and endotheliopathy in COVID-19
AB Pine, ML Meizlish, G Goshua, CH Chang, H Zhang, J Bishai, P Bahel, ...
Pulmonary Circulation 10 (4), 2045894020966547, 2020
1372020
Spatial profiling of chromatin accessibility in mouse and human tissues
Y Deng, M Bartosovic, S Ma, D Zhang, P Kukanja, Y Xiao, G Su, Y Liu, ...
Nature 609 (7926), 375-383, 2022
1312022
m6A modification prevents formation of endogenous double-stranded RNAs and deleterious innate immune responses during hematopoietic development
Y Gao, R Vasic, Y Song, R Teng, C Liu, R Gbyli, G Biancon, R Nelakanti, ...
Immunity 52 (6), 1007-1021. e8, 2020
1202020
Comorbidities and survival in a large cohort of patients with newly diagnosed myelodysplastic syndromes
R Wang, CP Gross, S Halene, X Ma
Leukemia research 33 (12), 1594-1598, 2009
1092009
Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes
Y Gao, E Smith, E Ker, P Campbell, E Cheng, S Zou, S Lin, L Wang, ...
Developmental cell 22 (3), 573-584, 2012
972012
Gaucher disease gene GBA functions in immune regulation
J Liu, S Halene, M Yang, J Iqbal, R Yang, WZ Mehal, WL Chuang, D Jain, ...
Proceedings of the National Academy of Sciences 109 (25), 10018-10023, 2012
912012
Gene therapy using hematopoietic stem cells: Sisyphus approaches the crest
S Halene, DB Kohn
Human gene therapy 11 (9), 1259-1267, 2000
852000
Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice
Y Saito, JM Ellegast, A Rafiei, Y Song, D Kull, M Heikenwalder, ...
Blood, The Journal of the American Society of Hematology 128 (14), 1829-1833, 2016
792016
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