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Robert T Abraham
Robert T Abraham
EVP and Head of Cancer Biology, Odyssey Therapeutics
Verified email at odysseytx.com
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13161*2021
Cell cycle checkpoint signaling through the ATM and ATR kinases
RT Abraham
Genes & development 15 (17), 2177-2196, 2001
27442001
The PI3K pathway in human disease
DA Fruman, H Chiu, BD Hopkins, S Bagrodia, LC Cantley, RT Abraham
Cell 170 (4), 605-635, 2017
20952017
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
AC Gingras, SP Gygi, B Raught, RD Polakiewicz, RT Abraham, ...
Genes & development 13 (11), 1422-1437, 1999
16311999
Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin
CC Hudson, M Liu, GG Chiang, DM Otterness, DC Loomis, F Kaper, ...
Molecular and cellular biology 22 (20), 7004-7014, 2002
15202002
A role for ATR in the DNA damage-induced phosphorylation of p53
RS Tibbetts, KM Brumbaugh, JM Williams, JN Sarkaria, WA Cliby, ...
Genes & development 13 (2), 152-157, 1999
14471999
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
JN Sarkaria, EC Busby, RS Tibbetts, P Roos, Y Taya, LM Karnitz, ...
Cancer research 59 (17), 4375-4382, 1999
13451999
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
GJ Brunn, CC Hudson, A Sekulic, JM Williams, H Hosoi, PJ Houghton, ...
Science 277 (5322), 99-101, 1997
12221997
Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells (∗)
CJ Sabers, MM Martin, GJ Brunn, JM Williams, FJ Dumont, G Wiederrecht, ...
Journal of Biological Chemistry 270 (2), 815-822, 1995
11291995
A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells
A Sekulic, CC Hudson, JL Homme, P Yin, DM Otterness, LM Karnitz, ...
Cancer research 60 (13), 3504-3513, 2000
9732000
Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase
G Powis, R Bonjouklian, MM Berggren, A Gallegos, R Abraham, ...
Cancer research 54 (9), 2419-2423, 1994
9331994
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002.
GJ Brunn, J Williams, C Sabers, G Wiederrecht, JC Lawrence Jr, ...
The EMBO journal 15 (19), 5256-5267, 1996
8891996
Immunopharmacology of rapamycin
RT Abraham, GJ Wiederrecht
Annual review of immunology 14 (1), 483-510, 1996
8851996
Jurkat T cells and development of the T-cell receptor signalling paradigm
RT Abraham, A Weiss
Nature reviews immunology 4 (4), 301-308, 2004
7652004
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
RS Tibbetts, D Cortez, KM Brumbaugh, R Scully, D Livingston, SJ Elledge, ...
Genes & development 14 (23), 2989-3002, 2000
6962000
Phosphorylation of Mammalian Target of Rapamycin (mTOR) at Ser-2448 IsMediated by p70S6 Kinase
GG Chiang, RT Abraham
Journal of Biological Chemistry 280 (27), 25485-25490, 2005
6642005
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
JN Sarkaria, RS Tibbetts, EC Busby, AP Kennedy, DE Hill, RT Abraham
Cancer research 58 (19), 4375-4382, 1998
6611998
PI 3-kinase related kinases:‘big’players in stress-induced signaling pathways
RT Abraham
DNA repair 3 (8-9), 883-887, 2004
6312004
Distinct requirements for Ras oncogenesis in human versus mouse cells
NM Hamad, JH Elconin, AE Karnoub, W Bai, JN Rich, RT Abraham, ...
Genes & development 16 (16), 2045-2057, 2002
5412002
Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference
C Zhu, J Zhao, M Bibikova, JD Leverson, E Bossy-Wetzel, JB Fan, ...
Molecular biology of the cell 16 (7), 3187-3199, 2005
5122005
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