Follow
Pietro Sormanni
Pietro Sormanni
Royal Society University Research Fellow, Department of Chemistry, University of Cambridge.
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
The CamSol method of rational design of protein mutants with enhanced solubility
P Sormanni, FA Aprile, M Vendruscolo
Journal of molecular biology 427 (2), 478-490, 2015
3122015
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, ...
Proceedings of the National Academy of Sciences 114 (6), E1009-E1017, 2017
2442017
MobiDB 3.0: more annotations for intrinsic disorder, conformational diversity and interactions in proteins
D Piovesan, F Tabaro, L Paladin, M Necci, I Mičetić, C Camilloni, N Davey, ...
Nucleic acids research 46 (D1), D471-D476, 2018
1852018
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms
S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, ...
Nature communications 10 (1), 1-11, 2019
1192019
Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method
FA Aprile, P Sormanni, M Perni, P Arosio, S Linse, TPJ Knowles, ...
Science advances 3 (6), e1700488, 2017
1142017
Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins
P Sormanni, FA Aprile, M Vendruscolo
Proceedings of the National Academy of Sciences 112 (32), 9902-9907, 2015
1102015
Simultaneous quantification of protein order and disorder
P Sormanni, D Piovesan, GT Heller, M Bonomi, P Kukic, C Camilloni, ...
Nature chemical biology 13 (4), 339-342, 2017
1032017
Rapid and accurate in silico solubility screening of a monoclonal antibody library
P Sormanni, L Amery, S Ekizoglou, M Vendruscolo, B Popovic
Scientific reports 7 (1), 1-9, 2017
942017
Parapred: antibody paratope prediction using convolutional and recurrent neural networks
E Liberis, P Veličković, P Sormanni, M Vendruscolo, P Liò
Bioinformatics 34 (17), 2944-2950, 2018
922018
A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer’s disease
R Freer, P Sormanni, G Vecchi, P Ciryam, CM Dobson, M Vendruscolo
Science advances 2 (8), e1600947, 2016
872016
The s2D method: simultaneous sequence-based prediction of the statistical populations of ordered and disordered regions in proteins
P Sormanni, C Camilloni, P Fariselli, M Vendruscolo
Journal of molecular biology 427 (4), 982-996, 2015
862015
Third generation antibody discovery methods: in silico rational design
P Sormanni, FA Aprile, M Vendruscolo
Chemical Society Reviews 47 (24), 9137-9157, 2018
822018
Proteome-wide observation of the phenomenon of life on the edge of solubility
G Vecchi, P Sormanni, B Mannini, A Vandelli, GG Tartaglia, CM Dobson, ...
Proceedings of the National Academy of Sciences 117 (2), 1015-1020, 2020
762020
Targeting disordered proteins with small molecules using entropy
GT Heller, P Sormanni, M Vendruscolo
Trends in biochemical sciences 40 (9), 491-496, 2015
762015
Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability
C Camilloni, BM Sala, P Sormanni, R Porcari, A Corazza, M De Rosa, ...
Scientific reports 6 (1), 1-11, 2016
562016
In vitro and in silico assessment of the developability of a designed monoclonal antibody library
AM Wolf Pérez, P Sormanni, JS Andersen, LI Sakhnini, I Rodriguez-Leon, ...
MAbs 11 (2), 388-400, 2019
552019
Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein
S Gianni, C Camilloni, R Giri, A Toto, D Bonetti, A Morrone, P Sormanni, ...
Proceedings of the National Academy of Sciences 111 (39), 14141-14146, 2014
532014
Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity
T Le Marchand, M de Rosa, N Salvi, BM Sala, LB Andreas, ...
Nature communications 9 (1), 1-11, 2018
492018
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez‐Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, ...
Angewandte Chemie International Edition 56 (47), 14963-14967, 2017
492017
Developability assessment of engineered monoclonal antibody variants with a complex self-association behavior using complementary analytical and in silico tools
L Shan, N Mody, P Sormani, KL Rosenthal, MM Damschroder, ...
Molecular pharmaceutics 15 (12), 5697-5710, 2018
472018
The system can't perform the operation now. Try again later.
Articles 1–20