| A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery MC Keogh, JA Kim, M Downey, J Fillingham, D Chowdhury, JC Harrison, ... Nature 439 (7075), 497-501, 2006 | 631 | 2006 |
| A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator M Downey, R Houlsworth, L Maringele, A Rollie, M Brehme, S Galicia, ... Cell 124 (6), 1155-1168, 2006 | 214 | 2006 |
| A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae SG Addinall, M Downey, M Yu, MK Zubko, J Dewar, A Leake, J Hallinan, ... Genetics 180 (4), 2251-2266, 2008 | 106 | 2008 |
| Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine DYL Mao, D Neculai, M Downey, S Orlicky, YZ Haffani, DF Ceccarelli, ... Molecular cell 32 (2), 259-275, 2008 | 106 | 2008 |
| γH2AX as a checkpoint maintenance signal M Downey, D Durocher Cell Cycle 5 (13), 1376-1381, 2006 | 83 | 2006 |
| Acetylome profiling reveals overlap in the regulation of diverse processes by sirtuins, gcn5, and esa1 M Downey, JR Johnson, NE Davey, BW Newton, TL Johnson, S Galaang, ... Molecular & Cellular Proteomics 14 (1), 162-176, 2015 | 79 | 2015 |
| A screen for candidate targets of lysine polyphosphorylation uncovers a conserved network implicated in ribosome biogenesis A Bentley-DeSousa, C Holinier, H Moteshareie, YC Tseng, S Kajjo, ... Cell reports 22 (13), 3427-3439, 2018 | 75 | 2018 |
| Gcn5 and sirtuins regulate acetylation of the ribosomal protein transcription factor Ifh1 M Downey, B Knight, AA Vashisht, CA Seller, JA Wohlschlegel, D Shore, ... Current biology 23 (17), 1638-1648, 2013 | 53 | 2013 |
| Polymerase stalling during replication, transcription and translation ER Edenberg, M Downey, D Toczyski Current Biology 24 (10), R445-R452, 2014 | 51 | 2014 |
| Chromatin and DNA repair: the benefits of relaxation M Downey, D Durocher Nature Cell Biology 8 (1), 9-10, 2006 | 47 | 2006 |
| Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis S Asif, RY Kim, T Fatica, J Sim, X Zhao, Y Oh, A Denoncourt, AC Cheung, ... Molecular metabolism 61, 101494, 2022 | 45 | 2022 |
| A broad respone to intracellular long-chain polyphosphate in human cells E Bondy-Chorney, I Abramchuk, R Nasser, C Holinier, A Denoncourt, ... Cell Reports 33 (4), 108318, 2020 | 44 | 2020 |
| Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme L Holland, M Downey, X Song, L Gauthier, P Bell‐Rogers, K Yankulov European journal of biochemistry 269 (21), 5192-5202, 2002 | 44 | 2002 |
| SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1 R Sebaa, J Johnson, C Pileggi, M Norgren, J Xuan, Y Sai, Q Tong, ... Molecular Metabolism 25, 35-49, 2019 | 41 | 2019 |
| Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin S McCracken, D Longman, E Marcon, P Moens, M Downey, JA Nickerson, ... Journal of Biological Chemistry 280 (51), 42227-42236, 2005 | 40 | 2005 |
| Non-histone protein acetylation by the evolutionarily conserved GCN5 and PCAF acetyltransferases M Downey Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1864 (2), 194608, 2021 | 36 | 2021 |
| Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation EM Da Costa, G Armaos, G McInnes, A Beaudry, G Moquin-Beaudry, ... Journal of Experimental & Clinical Cancer Research 38, 1-14, 2019 | 35 | 2019 |
| Model systems for studying polyphosphate biology: a focus on microorganisms A Denoncourt, M Downey Current Genetics, 1-16, 2021 | 34 | 2021 |
| Nonhistone targets of KAT2A and KAT2B implicated in cancer biology E Bondy-Chorney, A Denoncourt, Y Sai, M Downey Biochemistry and Cell Biology 97 (1), 30-45, 2019 | 30 | 2019 |
| Building a KATalogue of acetyllysine targeting and function M Downey, K Baetz Briefings in functional genomics 15 (2), 109-118, 2016 | 25 | 2016 |
