ZAP-70: an essential kinase in T-cell signaling H Wang, TA Kadlecek, BB Au-Yeung, HES Goodfellow, LY Hsu, ... Cold Spring Harbor perspectives in biology 2 (5), 2010 | 479 | 2010 |
The structure, regulation, and function of ZAP‐70 BB Au‐Yeung, S Deindl, LY Hsu, EH Palacios, SE Levin, J Kuriyan, ... Immunological reviews 228 (1), 41-57, 2009 | 269 | 2009 |
A sharp T-cell antigen receptor signaling threshold for T-cell proliferation BB Au-Yeung, J Zikherman, JL Mueller, JF Ashouri, M Matloubian, ... Proceedings of the National Academy of Sciences 111 (35), E3679-E3688, 2014 | 179 | 2014 |
Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4+ T cells JM Gardner, TC Metzger, EJ McMahon, BB Au-Yeung, AK Krawisz, W Lu, ... Immunity 39 (3), 560-572, 2013 | 177 | 2013 |
ZAP-70 in signaling, biology, and disease BB Au-Yeung, NH Shah, L Shen, A Weiss Annual review of immunology 36 (1), 127-156, 2018 | 145 | 2018 |
IL-2 modulates the TCR signaling threshold for CD8 but not CD4 T cell proliferation on a single-cell level BB Au-Yeung, GA Smith, JL Mueller, CS Heyn, RG Jaszczak, A Weiss, ... The Journal of Immunology 198 (6), 2445-2456, 2017 | 139 | 2017 |
A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity BB Au-Yeung, SE Levin, C Zhang, LY Hsu, DA Cheng, N Killeen, ... Nature immunology 11 (12), 1085-1092, 2010 | 122 | 2010 |
Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases S Mukherjee, J Zhu, J Zikherman, R Parameswaran, TA Kadlecek, ... Science signaling 6 (256), ra1-ra1, 2013 | 91 | 2013 |
A key role for Itk in both IFNγ and IL-4 production by NKT cells BB Au-Yeung, DJ Fowell The Journal of Immunology 179 (1), 111-119, 2007 | 84 | 2007 |
Cutting edge: Itk-dependent signals required for CD4+ T cells to exert, but not gain, Th2 effector function BB Au-Yeung, SD Katzman, DJ Fowell The Journal of Immunology 176 (7), 3895-3899, 2006 | 84 | 2006 |
Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development BB Au-Yeung, HJ Melichar, JO Ross, DA Cheng, J Zikherman, KM Shokat, ... Nature immunology 15 (7), 687-694, 2014 | 78 | 2014 |
Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns JO Ross, HJ Melichar, BB Au-Yeung, P Herzmark, A Weiss, EA Robey Proceedings of the National Academy of Sciences 111 (25), E2550-E2558, 2014 | 75 | 2014 |
A phosphosite within the SH2 domain of Lck regulates its activation by CD45 AH Courtney, JF Amacher, TA Kadlecek, MN Mollenauer, BB Au-Yeung, ... Molecular cell 67 (3), 498-511. e6, 2017 | 68 | 2017 |
Adaptation by naïve CD4+ T cells to self-antigen–dependent TCR signaling induces functional heterogeneity and tolerance WM Zinzow-Kramer, A Weiss, BB Au-Yeung Proceedings of the National Academy of Sciences 116 (30), 15160-15169, 2019 | 65 | 2019 |
The role of T cell receptor signaling thresholds in guiding T cell fate decisions J Zikherman, B Au-Yeung Current opinion in immunology 33, 43-48, 2015 | 64 | 2015 |
Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation H Phee, BB Au-Yeung, O Pryshchep, KL O'Hagan, SG Fairbairn, M Radu, ... Elife 3, e02270, 2014 | 59 | 2014 |
Itk controls the spatiotemporal organization of T cell activation KL Singleton, M Gosh, RD Dandekar, BB Au-Yeung, O Ksionda, ... Science signaling 4 (193), ra66-ra66, 2011 | 58 | 2011 |
Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL MR Jenkins, JC Stinchcombe, BB Au-Yeung, Y Asano, AT Ritter, A Weiss, ... Elife 3, e01310, 2014 | 52 | 2014 |
CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection C Come, A Cvrljevic, MM Khan, I Treise, T Adler, JA Aguilar-Pimentel, ... PLoS One 11 (4), e0152996, 2016 | 18 | 2016 |
Functional heterogeneity and adaptation of naive T cells in response to tonic TCR signals J Eggert, BB Au-Yeung Current opinion in immunology 73, 43-49, 2021 | 13 | 2021 |