Engineering extrinsic disorder to control protein activity in living cells O Dagliyan, M Tarnawski, PH Chu, D Shirvanyants, I Schlichting, ... Science 354 (6318), 1441-1444, 2016 | 231 | 2016 |
Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2 PH Chu, TY Huang, J Williams, DW Stafford Proceedings of the National Academy of Sciences 103 (51), 19308-19313, 2006 | 131 | 2006 |
A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells Y Chen, CA Tristan, L Chen, VM Jovanovic, C Malley, PH Chu, S Ryu, ... Nature methods 18 (5), 528-541, 2021 | 94 | 2021 |
Comprehensive analyses and prioritization of Tox21 10K chemicals affecting mitochondrial function by in-depth mechanistic studies M Xia, R Huang, Q Shi, WA Boyd, J Zhao, N Sun, JR Rice, PE Dunlap, ... Environmental health perspectives 126 (7), 077010, 2018 | 66 | 2018 |
Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms PH Chu, D Tsygankov, ME Berginski, O Dagliyan, SM Gomez, TC Elston, ... Proceedings of the National Academy of Sciences 111 (34), 12420-12425, 2014 | 63 | 2014 |
Dissecting motility signaling through activation of specific Src-effector complexes AV Karginov, D Tsygankov, M Berginski, PH Chu, ED Trudeau, JJ Yi, ... Nature chemical biology 10 (4), 286-290, 2014 | 59 | 2014 |
Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells CA Tristan, P Ormanoglu, J Slamecka, C Malley, PH Chu, VM Jovanovic, ... Stem Cell Reports 16 (12), 3076-3092, 2021 | 53 | 2021 |
An optogenetic tool for the activation of endogenous diaphanous‐related formins induces thickening of stress fibers without an increase in contractility MV Rao, PH Chu, KM Hahn, R Zaidel‐Bar Cytoskeleton 70 (7), 394-407, 2013 | 50 | 2013 |
Identification of an HptB-mediated multi-step phosphorelay in Pseudomonas aeruginosa PAO1 CT Lin, YJ Huang, PH Chu, JL Hsu, CH Huang, HL Peng Research in microbiology 157 (2), 169-175, 2006 | 46 | 2006 |
In vitro exposure systems and dosimetry assessment tools for inhaled tobacco products: workshop proceedings, conclusions and paths forward for in vitro model use H Behrsing, E Hill, H Raabe, R Tice, S Fitzpatrick, R Devlin, K Pinkerton, ... Alternatives to Laboratory Animals 45 (3), 117-158, 2017 | 28 | 2017 |
Scalable generation of sensory neurons from human pluripotent stem cells T Deng, VM Jovanovic, CA Tristan, C Weber, PH Chu, J Inman, S Ryu, ... Stem Cell Reports 18 (4), 1030-1047, 2023 | 25 | 2023 |
Stem cell-derived endothelial cell model that responds to tobacco smoke like primary endothelial cells PH Chu, G Chen, D Kuo, J Braisted, R Huang, Y Wang, A Simeonov, ... Chemical research in toxicology 33 (3), 751-763, 2020 | 15 | 2020 |
A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells VM Jovanovic, C Weber, J Slamecka, S Ryu, PH Chu, C Sen, J Inman, ... Stem Cell Reports 18 (8), 1701-1720, 2023 | 14 | 2023 |
User-friendly tools for quantifying the dynamics of cellular morphology and intracellular protein clusters D Tsygankov, PH Chu, H Chen, TC Elston, KM Hahn Methods in cell biology 123, 409-427, 2014 | 14 | 2014 |
Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail CA Tristan, H Hong, Y Jethmalani, Y Chen, C Weber, PH Chu, S Ryu, ... Nature protocols 18 (1), 58-80, 2023 | 13 | 2023 |
The MT1G Gene in LUHMES Neurons Is a Sensitive Biomarker of Neurotoxicity ZB Tong, J Braisted, PH Chu, D Gerhold Neurotoxicity research 38, 967-978, 2020 | 13 | 2020 |
Human pluripotent stem cells for high-throughput drug screening and characterization of small molecules S Ryu, PH Chu, C Malley, J Braisted, P Ormanoglu, R Huang, M Itkin, ... Induced Pluripotent Stem (iPS) Cells: Methods and Protocols, 811-827, 2021 | 6 | 2021 |
SEQUIN is an R/Shiny framework for rapid and reproducible analysis of RNA-seq data C Weber, MB Hirst, B Ernest, NJ Schaub, KM Wilson, K Wang, HM Baskir, ... Cell Reports Methods 3 (3), 2023 | 5 | 2023 |
Stress-free cell aggregation by using the CEPT cocktail enhances embryoid body and organoid fitness S Ryu, C Weber, PH Chu, B Ernest, VM Jovanovic, T Deng, J Slamecka, ... Biofabrication 16 (1), 015016, 2023 | 3 | 2023 |
Scalable generation of pseudo-unipolar sensory neurons from human pluripotent stem cells T Deng, CA Tristan, C Weber, PH Chu, S Ryu, VM Jovanovic, ... BioRxiv, 2022.03. 24.485622, 2022 | 3 | 2022 |