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John K. Walker
John K. Walker
Saint Louis University, Pfizer, University of Missouri-St. Louis
Verified email at slu.edu - Homepage
Title
Cited by
Cited by
Year
Broad anti-tumor activity of a small molecule that selectively targets the Warburg effect and lipogenesis
CA Flaveny, K Griffett, BEDM El-Gendy, M Kazantzis, M Sengupta, ...
Cancer cell 28 (1), 42-56, 2015
1972015
Reviving antibiotics: efflux pump inhibitors that interact with AcrA, a membrane fusion protein of the AcrAB-TolC multidrug efflux pump
N Abdali, JM Parks, KM Haynes, JL Chaney, AT Green, D Wolloscheck, ...
ACS infectious diseases 3 (1), 89-98, 2017
1042017
Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain
Z Chen, TM Doyle, L Luongo, TM Largent-Milnes, LA Giancotti, G Kolar, ...
Proceedings of the National Academy of Sciences 116 (21), 10557-10562, 2019
842019
Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase
SR Selness, RV Devraj, B Devadas, JK Walker, TL Boehm, RC Durley, ...
Bioorganic & medicinal chemistry letters 21 (13), 4066-4071, 2011
672011
Structural bioinformatics-based prediction of exceptional selectivity of p38 MAP kinase inhibitor PH-797804
L Xing, HS Shieh, SR Selness, RV Devraj, JK Walker, B Devadas, ...
Biochemistry 48 (27), 6402-6411, 2009
652009
Substituted pyridinones
B Devadas, J Walker, S Selness, T Boehm, R Durley, R Devraj, B Hickory, ...
US Patent App. 10/918,826, 2005
612005
Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa
CJ Cooper, G Krishnamoorthy, D Wolloscheck, JK Walker, VV Rybenkov, ...
ACS infectious diseases 4 (8), 1223-1234, 2018
592018
New fluorobutenolide templates for synthesis
TB Patrick, MV Lanahan, C Yang, JK Walker, CL Hutchinson, BE Neal
The Journal of Organic Chemistry 59 (5), 1210-1212, 1994
561994
Substituted pyridinones
B Devadas, J Walker, SR Selness, TL Boehm, RC Durley, R Devraj, ...
US Patent 7,067,540, 2006
552006
Identification and Structure–Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli
KM Haynes, N Abdali, V Jhawar, HI Zgurskaya, JM Parks, AT Green, ...
Journal of medicinal chemistry 60 (14), 6205-6219, 2017
542017
Substituted pyrazoles as p38 kinase inhibitors
AS Naraian, M Clare, PW Collins, JZ Crich, R Devraj, DL Flynn, L Geng, ...
US Patent 6,979,686, 2005
422005
Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold
AT Green, M Moniruzzaman, CJ Cooper, JK Walker, JC Smith, JM Parks, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (6), 129546, 2020
402020
Discovery and characterization of atropisomer PH‐797804, a p38 MAP kinase inhibitor, as a clinical drug candidate
L Xing, B Devadas, RV Devraj, SR Selness, H Shieh, JK Walker, M Mao, ...
ChemMedChem 7 (2), 273-280, 2012
382012
1-(2-(2, 2, 2-Trifluoroethoxy) ethyl-1H-pyrazolo [4, 3-d] pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors
MB Tollefson, BA Acker, EJ Jacobsen, RO Hughes, JK Walker, DNA Fox, ...
Bioorganic & medicinal chemistry letters 20 (10), 3125-3128, 2010
382010
Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase
SR Selness, RV Devraj, JB Monahan, TL Boehm, JK Walker, B Devadas, ...
Bioorganic & medicinal chemistry letters 19 (20), 5851-5856, 2009
362009
Therapeutic effect of a synthetic RORα/γ agonist in an animal model of autism
Y Wang, C Billon, JK Walker, TP Burris
ACS Chemical Neuroscience 7 (2), 143-148, 2016
352016
Acute Lymphoid and Gastrointestinal Toxicity Induced by Selective p38α Map Kinase and Map Kinase–Activated Protein Kinase-2 (MK2) Inhibitors in the Dog
DL Morris, SP O’Neil, RV Devraj, JP Portanova, RW Gilles, CJ Gross, ...
Toxicologic pathology 38 (4), 606-618, 2010
332010
Cationic [5+ 2] cycloaddition reactions promoted by trimethylsilyl triflate in highly polar media
JL Collins, PA Grieco, JK Walker
Tetrahedron letters 38 (8), 1321-1324, 1997
311997
Intramolecular cationic [5+ 2] cycloaddition reactions promoted by trimethylsilyl triflate in 3.0 M lithium perchlorate-ethyl acetate: Application to a formal total synthesis …
PA Grieco, JK Walker
Tetrahedron 53 (26), 8975-8996, 1997
281997
Multidrug efflux pumps and the two-faced Janus of substrates and inhibitors
HI Zgurskaya, JK Walker, JM Parks, VV Rybenkov
Accounts of chemical research 54 (4), 930-939, 2021
272021
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