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Colin Flaveny PhD
Colin Flaveny PhD
Principal Scientist Pfizer
Verified email at pfizer.com
Title
Cited by
Cited by
Year
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells
AE Boitano, J Wang, R Romeo, LC Bouchez, AE Parker, SE Sutton, ...
Science 329 (5997), 1345-1348, 2010
12262010
Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling
BC DiNatale, IA Murray, JC Schroeder, CA Flaveny, TS Lahoti, ...
Toxicological sciences 115 (1), 89-97, 2010
6432010
The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor
JC Schroeder, BC DiNatale, IA Murray, CA Flaveny, Q Liu, ...
Biochemistry 49 (2), 393-400, 2010
3122010
Broad anti-tumor activity of a small molecule that selectively targets the Warburg effect and lipogenesis
CA Flaveny, K Griffett, BEDM El-Gendy, M Kazantzis, M Sengupta, ...
Cancer cell 28 (1), 42-56, 2015
2002015
Ligand selectivity and gene regulation by the human aryl hydrocarbon receptor in transgenic mice
CA Flaveny, IA Murray, CR Chiaro, GH Perdew
Molecular pharmacology 75 (6), 1412-1420, 2009
1512009
Fluorophore-NanoLuc BRET Reporters Enable Sensitive In Vivo Optical Imaging and Flow Cytometry for Monitoring Tumorigenesis
FX Schaub, MS Reza, CA Flaveny, W Li, AM Musicant, S Hoxha, M Guo, ...
Cancer research 75 (23), 5023-5033, 2015
1212015
Differential gene regulation by the human and mouse aryl hydrocarbon receptor
CA Flaveny, IA Murray, GH Perdew
Toxicological Sciences 114 (2), 217-225, 2010
1202010
Ah receptor represses acute-phase response gene expression without binding to its cognate response element
RD Patel, IA Murray, CA Flaveny, A Kusnadi, GH Perdew
Laboratory investigation 89 (6), 695-707, 2009
1202009
Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity
IA Murray, JL Morales, CA Flaveny, BC DiNatale, C Chiaro, K Gowdahalli, ...
Molecular pharmacology 77 (2), 247-254, 2010
1172010
The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis
K Griffett, RD Welch, CA Flaveny, GR Kolar, BA Neuschwander-Tetri, ...
Molecular metabolism 4 (4), 353-357, 2015
872015
Pyrvinium attenuates Hedgehog signaling downstream of smoothened
B Li, DL Fei, CA Flaveny, N Dahmane, V Baubet, Z Wang, F Bai, XH Pei, ...
Cancer research 74 (17), 4811-4821, 2014
842014
Transgenic humanized AHR mouse reveals differences between human and mouse AHR ligand selectivity
CA Flaveny, GH Perdew
Molecular and cellular pharmacology 1 (3), 119, 2009
842009
Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties
IA Murray, G Krishnegowda, BC DiNatale, C Flaveny, C Chiaro, JM Lin, ...
Chemical research in toxicology 23 (5), 955-966, 2010
812010
Antagonism of aryl hydrocarbon receptor signaling by 6, 2′, 4′-trimethoxyflavone
IA Murray, CA Flaveny, BC DiNatale, CR Chairo, JC Schroeder, ...
Journal of Pharmacology and Experimental Therapeutics 332 (1), 135-144, 2010
772010
Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis
B Li, CA Flaveny, C Giambelli, DL Fei, L Han, BI Hang, F Bai, XH Pei, ...
PloS one 9 (7), e101969, 2014
672014
The mouse and human Ah receptor differ in recognition of LXXLL motifs
C Flaveny, RK Reen, A Kusnadi, GH Perdew
Archives of biochemistry and biophysics 471 (2), 215-223, 2008
602008
Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3′, 4′-dimethoxy-α-naphthoflavone
IA Murray, CA Flaveny, CR Chiaro, AK Sharma, RS Tanos, JC Schroeder, ...
Molecular Pharmacology 79 (3), 508-519, 2011
592011
Hedgehog signaling regulates bladder cancer growth and tumorigenicity
DL Fei, A Sanchez-Mejias, Z Wang, C Flaveny, J Long, S Singh, ...
Cancer research 72 (17), 4449-4458, 2012
572012
Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract
S Sur, H Nakanishi, C Flaveny, JE Ippolito, J McHowat, DA Ford, RB Ray
Cell Communication and Signaling 17, 1-13, 2019
562019
LXR-inverse agonism stimulates immune-mediated tumor destruction by enhancing CD8 T-cell activity in triple negative breast cancer
KJ Carpenter, AC Valfort, N Steinauer, A Chatterjee, S Abuirqeba, ...
Scientific reports 9 (1), 19530, 2019
492019
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