Heparan sulfate proteoglycans biosynthesis and post synthesis mechanisms combine few enzymes and few core proteins to generate extensive structural and functional diversity T Annaval, R Wild, Y Crétinon, R Sadir, RR Vivès, H Lortat-Jacob Molecules 25 (18), 4215, 2020 | 64 | 2020 |
Characterization of Intersubunit Communication in the Virginiamycin trans-Acyl Transferase Polyketide Synthase J Dorival, T Annaval, F Risser, S Collin, P Roblin, C Jacob, A Gruez, ... Journal of the American Chemical Society 138 (12), 4155-4167, 2016 | 46 | 2016 |
Evaluating ketoreductase exchanges as a means of rationally altering polyketide stereochemistry T Annaval, C Paris, PF Leadlay, C Jacob, KJ Weissman ChemBioChem 16 (9), 1357-1364, 2015 | 45 | 2015 |
Comparative studies of the biosynthetic gene clusters for anthraquinone-fused enediynes shedding light into the tailoring steps of tiancimycin biosynthesis X Yan, JJ Chen, A Adhikari, CN Teijaro, H Ge, I Crnovcic, CY Chang, ... Organic Letters 20 (18), 5918-5921, 2018 | 39 | 2018 |
ADAPTABLE: A comprehensive web platform of antimicrobial peptides tailored to the user’s research F Ramos-Martín, T Annaval, S Buchoux, C Sarazin, N D’amelio Life science alliance 2 (6), 2019 | 28 | 2019 |
Resistance to enediyne antitumor antibiotics by sequestration CY Chang, X Yan, I Crnovcic, T Annaval, C Chang, B Nocek, JD Rudolf, ... Cell chemical biology 25 (9), 1075-1085. e4, 2018 | 23 | 2018 |
Biochemical and structural characterization of TtnD, a prenylated FMN-dependent decarboxylase from the tautomycetin biosynthetic pathway T Annaval, L Han, JD Rudolf, G Xie, D Yang, CY Chang, M Ma, I Crnovcic, ... ACS Chemical Biology 13 (9), 2728-2738, 2018 | 23 | 2018 |
Characterization of TnmH as an O-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody … A Adhikari, CN Teijaro, X Yan, CY Chang, C Gui, YC Liu, I Crnovcic, ... Journal of medicinal chemistry 63 (15), 8432-8441, 2020 | 19 | 2020 |
Discovery of alternative producers of the enediyne antitumor antibiotic C-1027 with high titers X Yan, Hindra, H Ge, D Yang, T Huang, I Crnovcic, CY Chang, SM Fang, ... Journal of natural products 81 (3), 594-599, 2018 | 14 | 2018 |
Crystal structure of thioesterase SgcE10 supporting common polyene intermediates in 9-and 10-membered enediyne core biosynthesis T Annaval, JD Rudolf, CY Chang, JR Lohman, Y Kim, L Bigelow, ... ACS omega 2 (8), 5159-5169, 2017 | 12 | 2017 |
Cytochrome P450 hydroxylase TnmL catalyzing sequential hydroxylation with an additional proofreading activity in tiancimycin biosynthesis T Annaval, CN Teijaro, A Adhikari, X Yan, JJ Chen, I Crnovcic, D Yang, ... ACS chemical biology 16 (7), 1172-1178, 2021 | 10 | 2021 |
Hindra; Babnigg, G.; et al CY Chang, X Yan, I Crnovcic, T Annaval, C Chang, B Nocek, JD Rudolf, ... Resistance to enediyne antitumor antibiotics by sequestration. Cell Chem …, 2018 | 7 | 2018 |
Antimicrobial bombinin-like peptide 3 selectively recognizes and inserts into bacterial biomimetic bilayers in multiple steps T Annaval, F Ramos-Martin, C Herrera-Leon, M Adelaide, V Antonietti, ... Journal of Medicinal Chemistry 64 (8), 5185-5197, 2021 | 6 | 2021 |
Functional characterization of cytochrome P450 hydroxylase YpmL in yangpumicin A biosynthesis and its application for anthraquinone-fused enediyne structural diversification D Yang, F Ye, CN Teijaro, D Hwang, T Annaval, A Adhikari, G Li, X Yan, ... Organic letters 24 (5), 1219-1223, 2022 | 4 | 2022 |
Functional and structural insights into human N‐deacetylase/N‐sulfotransferase activities SD Vallet, T Annaval, RR Vives, E Richard, J Hénault, C Le Narvor, ... Proteoglycan Research 1 (3), e8, 2023 | 3 | 2023 |
Étude multidisciplinaire des aspects clés de la biosynthèse des polykétides par des polykétide synthases modulaires T Annaval Université de Lorraine, 2015 | 1 | 2015 |
Discovery and diversification of tiancimycin (TMN) natural products for Antibody Drug Conjugates (ADCs) C Teijaro, A Adhikari, X Yan, T Annaval, I Crnovcic, CY Chang, C Rader, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
ADAPTABLE: a web platform for antimicrobial peptides F Ramos-Martin, T Annaval, S Buchoux, C Sarazin, N d'Amelio European Biophysics Journal 48 (1), S224, 2019 | | 2019 |
Enediyne diversification by a cofactor-promiscuous methyltransferase A Adhikari, X Yan, T Annaval, I Crnovcic, CY Chang, B Shen Natural Product Discovery and Development in the Genomic Era, 2018 | | 2018 |
Comparative studies of the biosynthetic pathways for anthraquinone-fused enediynes X Yan, J Chen, T Annaval, A Adhikari, I Crnovcic, CY Chang, D Yang, ... Natural Product Discovery and Development in the Genomic Era, 2018 | | 2018 |