Alejandro J. Vila
Alejandro J. Vila
IBR (Instituto de Biologia Molecular y Celular de Rosario), CONICET-UNR
Verified email at - Homepage
Cited by
Cited by
Nuclear magnetic resonance of paramagnetic metalloproteins
I Bertini, P Turano, AJ Vila
Chemical reviews 93 (8), 2833-2932, 1993
Metallo-β-lactamases: novel weaponry for antibiotic resistance in bacteria
MW Crowder, J Spencer, AJ Vila
Accounts of chemical research 39 (10), 721-728, 2006
Mitochondrial cytochrome c oxidase biogenesis: Recent developments
A Timón-Gómez, E Nývltová, LA Abriata, AJ Vila, J Hosler, A Barrientos
Seminars in cell & developmental biology 76, 163-178, 2018
Can ceftazidime-avibactam and aztreonam overcome β-lactam resistance conferred by metallo-β-lactamases in Enterobacteriaceae?
S Marshall, AM Hujer, LJ Rojas, KM Papp-Wallace, RM Humphries, ...
Antimicrobial agents and chemotherapy 61 (4), 10.1128/aac. 02243-16, 2017
Membrane anchoring stabilizes and favors secretion of New Delhi metallo-β-lactamase
LJ González, G Bahr, TG Nakashige, EM Nolan, RA Bonomo, AJ Vila
Nature chemical biology 12 (7), 516-522, 2016
Overcoming differences: The catalytic mechanism of metallo-β-lactamases
MR Meini, LI Llarrull, AJ Vila
FEBS letters 589 (22), 3419-3432, 2015
Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes
P Hinchliffe, MM González, MF Mojica, JM González, V Castillo, C Saiz, ...
Proceedings of the National Academy of Sciences 113 (26), E3745-E3754, 2016
The iron-sulfur cluster (Fe4S4) centers in ferredoxins studied through proton and carbon hyperfine coupling. Sequence-specific assignments of cysteines in ferredoxins from …
I Bertini, F Capozzi, C Luchinat, M Piccioli, AJ Vila
Journal of the American Chemical Society 116 (2), 651-660, 1994
Spectroscopic characterization of a binuclear metal site in Bacillus cereus β-lactamase II
EG Orellano, JE Girardini, JA Cricco, EA Ceccarelli, AJ Vila
Biochemistry 37 (28), 10173-10180, 1998
Metallo-β-lactamases in the age of multidrug resistance: from structure and mechanism to evolution, dissemination, and inhibitor design
G Bahr, LJ Gonzalez, AJ Vila
Chemical reviews 121 (13), 7957-8094, 2021
The urgent need for metallo-β-lactamase inhibitors: an unattended global threat
MF Mojica, MA Rossi, AJ Vila, RA Bonomo
The Lancet Infectious Diseases 22 (1), e28-e34, 2022
Mechanism of CuA assembly
LA Abriata, L Banci, I Bertini, S Ciofi-Baffoni, P Gkazonis, GA Spyroulias, ...
Nature chemical biology 4 (10), 599-601, 2008
A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases
MN Lisa, AR Palacios, M Aitha, MM González, DM Moreno, MW Crowder, ...
Nature communications 8 (1), 538, 2017
Structural basis of lipid biosynthesis regulation in Gram‐positive bacteria
GE Schujman, M Guerin, A Buschiazzo, F Schaeffer, LI Llarrull, G Reh, ...
The EMBO journal 25 (17), 4074-4083, 2006
Bisthiazolidines: a substrate-mimicking scaffold as an inhibitor of the NDM-1 carbapenemase
MM González, M Kosmopoulou, MF Mojica, V Castillo, P Hinchliffe, ...
ACS infectious diseases 1 (11), 544-554, 2015
Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility
PE Tomatis, SM Fabiane, F Simona, P Carloni, BJ Sutton, AJ Vila
Proceedings of the National Academy of Sciences 105 (52), 20605-20610, 2008
Sensitive EDTA-based microbiological assays for detection of metallo-β-lactamases in nonfermentative gram-negative bacteria
P Marchiaro, MA Mussi, V Ballerini, F Pasteran, AM Viale, AJ Vila, ...
Journal of Clinical Microbiology 43 (11), 5648-5652, 2005
Nitration of solvent-exposed tyrosine 74 on cytochrome c triggers heme iron-methionine 80 bond disruption: nuclear magnetic resonance and optical spectroscopy studies
LA Abriata, A Cassina, V Tortora, M Marín, JM Souza, L Castro, AJ Vila, ...
Journal of Biological Chemistry 284 (1), 17-26, 2009
Mimicking natural evolution in metallo-β-lactamases through second-shell ligand mutations
PE Tomatis, RM Rasia, L Segovia, AJ Vila
Proceedings of the National Academy of Sciences 102 (39), 13761-13766, 2005
Water-assisted reaction mechanism of monozinc β-lactamases
M Dal Peraro, LI Llarrull, U Rothlisberger, AJ Vila, P Carloni
Journal of the American Chemical Society 126 (39), 12661-12668, 2004
The system can't perform the operation now. Try again later.
Articles 1–20