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Abdelsattar Mansour Ebeid Omar
Abdelsattar Mansour Ebeid Omar
Professor of Medicinal Chemistry, Faculty of Pharmacy, King Abdulaziz University
Verified email at kau.edu.sa
Title
Cited by
Cited by
Year
Design, Synthesis and in Vivo Anti-inflammatory Activities of 2,4-Diaryl-5-4H-imidazolone Derivatives
M El-Araby, A Omar, HH Hassanein, AGH El-Helby, AA Abdel-Rahman
Molecules 17 (10), 12262-12275, 2012
642012
Novel scaffold hopping of potent benzothiazole and isatin analogues linked to 1, 2, 3-triazole fragment that mimic quinazoline epidermal growth factor receptor inhibitors …
N Rezki, MA Almehmadi, S Ihmaid, AM Shehata, AM Omar, HEA Ahmed, ...
Bioorganic Chemistry 103, 104133, 2020
612020
Synthesis and screening of some new fluorinated quinazolinone–sulphonamide hybrids as anticancer agents
MF Zayed, HEA Ahmed, S Ihmaid, ASM Omar, AS Abdelrahim
Journal of Taibah University Medical Sciences 10 (3), 333-339, 2015
472015
Design, synthesis, molecular docking of new lipophilic acetamide derivatives affording potential anticancer and antimicrobial agents
HEA Ahmed, SK Ihmaid, AM Omar, AM Shehata, HS Rateb, MF Zayed, ...
Bioorganic chemistry 76, 332-342, 2018
462018
In vitro and computational investigations of novel synthetic carboxamide-linked pyridopyrrolopyrimidines with potent activity as SARS-CoV-2-M Pro inhibitors
A Aljuhani, HEA Ahmed, SK Ihmaid, AM Omar, SS Althagfan, ...
RSC advances 12 (41), 26895-26907, 2022
422022
Crystal structure of carbonmonoxy sickle hemoglobin in R-state conformation
MS Ghatge, MH Ahmed, ASM Omar, PP Pagare, S Rosef, GE Kellogg, ...
Journal of structural biology 194 (3), 446-450, 2016
392016
Design, synthesis, and biological evaluation studies of novel quinazolinone derivatives as anticonvulsant agents
MF Zayed, HEA Ahmed, ASM Omar, AS Abdelrahim, K El-Adl
Medicinal Chemistry Research 22, 5823-5831, 2013
352013
The rational design, synthesis, and antimicrobial investigation of 2-Amino-4-Methylthiazole analogues inhibitors of GlcN-6-P synthase
AM Omar, S Ihmaid, ESE Habib, SS Althagfan, S Ahmed, HS Abulkhair, ...
Bioorganic Chemistry 99, 103781, 2020
342020
Synthesis, modelling, and anticonvulsant studies of new quinazolines showing three highly active compounds with low toxicity and high affinity to the GABA-A receptor
MF Zayed, SK Ihmaid, HEA Ahmed, K El-Adl, AM Asiri, AM Omar
Molecules 22 (2), 188, 2017
322017
Antimicrobial screening and pharmacokinetic profiling of novel phenyl-[1, 2, 4] triazolo [4, 3-a] quinoxaline analogues targeting DHFR and E. coli DNA gyrase B
AM Omar, M Alswah, HEA Ahmed, AH Bayoumi, KM El-Gamal, A El-Morsy, ...
Bioorganic Chemistry 96, 103656, 2020
282020
Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell …
AM Omar, J Bajorath, S Ihmaid, HM Mohamed, AM El-Agrody, A Mora, ...
Bioorganic Chemistry 101, 103992, 2020
272020
Molecular mimics of classic p-glycoprotein inhibitors as multidrug resistance suppressors and their synergistic effect on paclitaxel
ME El-Araby, AM Omar, MT Khayat, HA Assiri, AM Al-Abd
PLoS One 12 (1), e0168938, 2017
272017
Identification of a novel class of covalent modifiers of hemoglobin as potential antisickling agents
AM Omar, MA Mahran, MS Ghatge, N Chowdhury, FHA Bamane, ...
Organic & biomolecular chemistry 13 (22), 6353-6370, 2015
262015
Thiophenes—naturally occurring plant metabolites: Biological activities and in silico evaluation of their potential as cathepsin D inhibitors
SRM Ibrahim, AM Omar, AA Bagalagel, RM Diri, AO Noor, DM Almasri, ...
Plants 11 (4), 539, 2022
252022
Inborn errors in the vitamin B6 salvage enzymes associated with neonatal epileptic encephalopathy and other pathologies
MS Ghatge, M Al Mughram, AM Omar, MK Safo
Biochimie 183, 18-29, 2021
212021
Chaetomugilins and chaetoviridins—promising natural metabolites: structures, separation, characterization, biosynthesis, bioactivities, molecular docking, and molecular dynamics
AM Omar, GA Mohamed, SRM Ibrahim
Journal of Fungi 8 (2), 127, 2022
182022
Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect
TS Ibrahim, MM Hawwas, AM Malebari, ES Taher, AM Omar, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 802-818, 2021
182021
VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions
O Abdulmalik, PP Pagare, B Huang, GG Xu, MS Ghatge, X Xu, Q Chen, ...
Scientific Reports 10 (1), 20277, 2020
182020
Potent quinoline-containing combretastatin a-4 analogues: design, synthesis, antiproliferative, and anti-tubulin activity
TS Ibrahim, MM Hawwas, AM Malebari, ES Taher, AM Omar, NM O’boyle, ...
Pharmaceuticals 13 (11), 393, 2020
172020
Phytoconstituents, in vitro anti-infective activity of Buddleja indica Lam., and in silico evaluation of its SARS-CoV-2 inhibitory potential
FS Youssef, AE Altyar, AM Omar, ML Ashour
Frontiers in Pharmacology 12, 619373, 2021
122021
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Articles 1–20