Ashraf N. Abdalla, Ph.D.
Ashraf N. Abdalla, Ph.D.
Umm Al-Qura University, College of Pharmacy, Associate Professor of Pharmacology
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Antitumor activity of pyrrolizines and their Cu (II) complexes: Design, synthesis and cytotoxic screening with potential apoptosis-inducing activity
AM Gouda, HA El-Ghamry, TM Bawazeer, TA Farghaly, AN Abdalla, ...
European journal of medicinal chemistry 145, 350-359, 2018
Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2
ASEA Hamad M.Alkahtani, Ashraf N.Abdalla, Ahmad J.Obaidullah, Mohammed M ...
Bioorganic chemistry 2019, 2019
Optimization of pyrrolizine-based Schiff bases with 4-thiazolidinone motif: Design, synthesis and investigation of cytotoxicity and anti-inflammatory potency
AMG Ahmed M. Shawky, Mohammed A.S. Abourehab, Ashraf N. Abdalla
European journal of medicinal chemistry, 2019
Triterpenoidal saponins from the fruits of Gleditsia caspica with proapoptotic properties
U Shaheen, EA Ragab, AN Abdalla, A Bader
Phytochemistry 145, 168-178, 2018
Reprofiling of full‐length phosphonated carbocyclic 2′‐oxa‐3′‐aza‐nucleosides toward antiproliferative agents: Synthesis, antiproliferative activity, and molecular docking study
MM Bkhaitan, AZ Mirza, AN Abdalla, H Shamshad, Z Ul‐Haq, M Alarjah, ...
Chemical biology & drug design 90 (5), 679-689, 2017
Pyrrolizines: design, synthesis, anticancer evaluation and investigation of the potential mechanism of action
AM Gouda, AH Abdelazeem, HA Omar, AN Abdalla, MAS Abourehab, ...
Bioorganic & medicinal chemistry 25 (20), 5637-5651, 2017
Proapoptotic activity of Achillea membranacea essential oil and its major constituent 1, 8-cineole against A2780 ovarian cancer cells
AN Abdalla, U Shaheen, Q Abdallah, G Flamini, MM Bkhaitan, ...
Molecules 25 (7), 1582, 2020
Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities
KM Attalah, AN Abdalla, A Aslam, M Ahmed, MAS Abourehab, NA ElSawy, ...
Bioorganic chemistry 94, 103371, 2020
Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5, 5-diphenylimidazolidine-2, 4-dione derivatives: Molecular docking studies
HM Alkahtani, MM Alanazi, FS Aleanizy, FY Alqahtani, A Alhoshani, ...
Saudi Pharmaceutical Journal 27 (5), 682-693, 2019
Pyrrolizine-5-carboxamides: Exploring the impact of various substituents on the anti-inflammatory and anticancer activities
AM Gouda, AH Abdelazeem, AN Abdalla, M Ahmed
Acta Pharmaceutica 68 (3), 251-273, 2018
Synthesis and biological evaluation of benzyl styrylsulfonyl derivatives as potent anticancer mitotic inhibitors
O Chahrour, A Abdalla, F Lam, C Midgley, S Wang
Bioorganic & medicinal chemistry letters 21 (10), 3066-3069, 2011
Structural-based design, synthesis, and antitumor activity of novel alloxazine analogues with potential selective kinase inhibition
WH Malki, AM Gouda, HEA Ali, R Al-Rousan, D Samaha, AN Abdalla, ...
European journal of medicinal chemistry 152, 31-52, 2018
Effect of fluorescein angiography on renal functions in type 2 diabetes patients: A pilot study
WH Almalki, AN Abdalla, AF Elkeraie, AM Abdelhadi, M Elrggal, ...
Saudi Journal of Kidney Diseases and Transplantation 28 (3), 491, 2017
Phytochemical, cytotoxic, and antimicrobial evaluation of the fruits of miswak plant, Salvadora persica L.
M Al Bratty, HA Makeen, HA Alhazmi, SM Syame, AN Abdalla, ...
Journal of Chemistry 2020, 2020
Preparation and biological evaluation of metronidazole derivatives with monoterpenes and eugenol
MM Bkhaitan, M Alarjah, AZ Mirza, AN Abdalla, HM El‐Said, HS Faidah
Chemical biology & drug design 92 (6), 1954-1962, 2018
Phytochemical Screening and Cytotoxic Properties of Ethanolic Extract of Young and Mature Khat Leaves
6 Rashad Alsanosy,1,2 Hassan A. Alhazmi ,1,3 Shahnaz Sultana,4 Ashraf N ...
Journal of chemistry 7897435, 2020
A Series of Isatin-Hydrazones with Cytotoxic Activity and CDK2 Kinase Inhibitory Activity: A Potential Type II ATP Competitive Inhibitor
HS Al-Salem, M Arifuzzaman, HM Alkahtani, AN Abdalla, IS Issa, ...
Molecules 25 (19), 4400, 2020
Tamoxifen and the PI3K inhibitor: LY294002 synergistically induce apoptosis and cell cycle arrest in breast cancer MCF-7 cells
ME Abdallah, MZ El-Readi, MA Althubiti, RA Almaimani, AM Ismail, S Idris, ...
Molecules 25 (15), 3355, 2020
Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential …
AM Shawky, NA Ibrahim, MAS Abourehab, AN Abdalla, AM Gouda
Journal of enzyme inhibition and medicinal chemistry 36 (1), 15-33, 2021
Significance of Targeting VEGFR-2 and Cyclin D1 in Luminal-A Breast Cancer
AN Abdalla, A Qattan, WH Malki, I Shahid, MA Hossain, M Ahmed
Molecules 25 (20), 4606, 2020
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