Edward K. Weir
Edward K. Weir
Professor of Medicine, University of Minnesota
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Cited by
Cited by
Cellular and molecular pathobiology of pulmonary arterial hypertension
M Humbert, NW Morrell, SL Archer, KR Stenmark, MR MacLean, IM Lang, ...
Journal of the American College of Cardiology 43 (12S), S13-S24, 2004
Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase.
SL Archer, JM Huang, V Hampl, DP Nelson, PJ Shultz, EK Weir
Proceedings of the National Academy of Sciences 91 (16), 7583-7587, 1994
Cellular and molecular basis of pulmonary arterial hypertension
NW Morrell, S Adnot, SL Archer, J Dupuis, P Lloyd Jones, MR MacLean, ...
Journal of the American College of Cardiology 54 (1_Supplement_S), S20-S31, 2009
An abnormal mitochondrial–hypoxia inducible factor-1α–Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities …
S Bonnet, ED Michelakis, CJ Porter, MA Andrade-Navarro, B Thébaud, ...
Circulation 113 (22), 2630-2641, 2006
Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies
SL Archer, EK Weir, MR Wilkins
Circulation 121 (18), 2045-2066, 2010
Acute oxygen-sensing mechanisms
EK Weir, J López-Barneo, KJ Buckler, SL Archer
New England Journal of Medicine 353 (19), 2042-2055, 2005
Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction
JM Post, JR Hume, SL Archer, EK Weir
American Journal of Physiology-Cell Physiology 262 (4), C882-C890, 1992
The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels
EK Weir, SL Archer
The FASEB journal 9 (2), 183-189, 1995
A redox-based O2 sensor in rat pulmonary vasculature.
SL Archer, J Huang, T Henry, D Peterson, EK Weir
Circulation research 73 (6), 1100-1112, 1993
Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1α-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and …
SL Archer, M Gomberg-Maitland, ML Maitland, S Rich, JGN Garcia, ...
American Journal of Physiology-Heart and Circulatory Physiology 294 (2 …, 2008
Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia
SL Archer, JMC Huang, HL Reeve, V Hampl, S Tolarová, E Michelakis, ...
Circulation research 78 (3), 431-442, 1996
Dynamin-related protein 1–mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary …
G Marsboom, PT Toth, JJ Ryan, Z Hong, X Wu, YH Fang, T Thenappan, ...
Circulation research 110 (11), 1484-1497, 2012
O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase
SL Archer, HL Reeve, E Michelakis, L Puttagunta, R Waite, DP Nelson, ...
Proceedings of the National Academy of Sciences 96 (14), 7944-7949, 1999
Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor
SL Archer, JP Tolins, L Raij, EK Weir
Biochemical and biophysical research communications 164 (3), 1198-1205, 1989
Impact of TASK-1 in human pulmonary artery smooth muscle cells
A Olschewski, Y Li, B Tang, J Hanze, B Eul, RM Bohle, J Wilhelm, ...
Circulation research 98 (8), 1072-1080, 2006
Does vitamin D deficiency increase the severity of COVID-19?
EK Weir, T Thenappan, M Bhargava, Y Chen
Clinical Medicine 20 (4), e107, 2020
Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction
EK Weir, HL Reeve, JMC Huang, E Michelakis, DP Nelson, V Hampl, ...
Circulation 94 (9), 2216-2220, 1996
The acute administration of vasodilators in primary pulmonary hypertension: experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension
EK Weir, LJ Rubin, SM Ayres, EH Bergofsky, BH Brundage, KM Detre, ...
American Review of Respiratory Disease, 2012
Coexistent pulmonary and portal hypertension: morphologic and clinical features
BS Edwards, EK Weir, WD Edwards, J Ludwig, RK Dykoski, JE Edwards
Journal of the American College of Cardiology 10 (6), 1233-1238, 1987
Cytokine-induced differentiation of multipotent adult progenitor cells into functional smooth muscle cells
JJ Ross, Z Hong, B Willenbring, L Zeng, B Isenberg, EH Lee, M Reyes, ...
The Journal of clinical investigation 116 (12), 3139-3149, 2006
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