Mahmoud El Hassab
Mahmoud El Hassab
lecturer assistant of medicinal chemistry, King Salman international University
Verified email at - Homepage
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Development of isatin-thiazolo [3, 2-a] benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and …
WM Eldehna, MA El Hassab, MF Abo-Ashour, T Al-Warhi, MM Elaasser, ...
Bioorganic Chemistry 110, 104748, 2021
Identification of Novel Cyanopyridones and Pyrido[2,3-d]pyrimidines as Anticancer Agents with Dual VEGFR-2/HER-2 Inhibitory Action: Synthesis, Biological …
T Al-Warhi, AAM Sallam, LR Hemeda, MA El Hassab, N Aljaeed, ...
Pharmaceuticals 15 (10), 1262, 2022
GC/MS Profiling, Anti-Collagenase, Anti-Elastase, Anti-Tyrosinase and Anti-Hyaluronidase Activities of a Stenocarpus sinuatus Leaves Extract
MM Younis, IM Ayoub, NM Mostafa, MA El Hassab, WM Eldehna, ...
Plants 11 (7), 918, 2022
Multi-step in silico discovery of natural drugs against COVID-19 targeting main protease
EB Elkaeed, FS Youssef, IH Eissa, H Elkady, AA Alsfouk, ML Ashour, ...
International Journal of Molecular Sciences 23 (13), 6912, 2022
In silico identification of novel SARS-COV-2 2′-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches
MA El Hassab, TM Ibrahim, ST Al-Rashood, A Alharbi, RO Eskandrani, ...
Journal of enzyme inhibition and medicinal chemistry 36 (1), 727-736, 2021
Development of novel isatin–nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing–bacteria
ZM Elsayed, WM Eldehna, MM Abdel-Aziz, MA El Hassab, EB Elkaeed, ...
Journal of enzyme inhibition and medicinal chemistry 36 (1), 384-392, 2021
Identification of a New Potential SARS-COV-2 RNA-Dependent RNA Polymerase Inhibitor via Combining Fragment-Based Drug Design, Docking, Molecular …
MA El Hassab, AA Shoun, ST Al-Rashood, T Al-Warhi, WM Eldehna
Frontiers in Chemistry 8, 584894, 2020
Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4, 5-dihydropyrazoles as anticancer agents with potential EGFR …
WM Eldehna, MA El Hassab, ZM Elsayed, T Al-Warhi, H Elkady, ...
Scientific reports 12 (1), 12821, 2022
Olive leaves as a potential phytotherapy in the treatment of COVID-19 disease; A mini-review
SM Abdelgawad, MAE Hassab, MAS Abourehab, EB Elkaeed, ...
Frontiers in pharmacology 13, 879118, 2022
Toward the identification of potential α-ketoamide covalent inhibitors for SARS-CoV-2 main protease: Fragment-based drug design and MM-PBSA calculations
MAE Hassab, M Fares, MKAH Amin, ST Al-Rashood, A Alharbi, ...
Processes 9 (6), 1004, 2021
Identification of potential inhibitors for HCV NS3 genotype 4a by combining protein–ligand interaction fingerprint, 3D pharmacophore, docking, and dynamic simulation
MAEM El-Hasab, EE El-Bastawissy, TF El-Moselhy
Journal of Biomolecular Structure and Dynamics 36 (7), 1713-1727, 2018
Direct acting anti-hepatitis C combinations as potential COVID-19 protease inhibitors
M Hamed, M El-Hasab, FR Mansour
VirusDisease 32 (2), 279-285, 2021
Chemical Constituents, Antioxidant, and Enzyme Inhibitory Activities Supported by In-Silico Study of n-Hexane Extract and Essential Oil of Guava Leaves
SH Aly, OA Eldahshan, ST Al-Rashood, FA Binjubair, MA El Hassab, ...
Molecules 27 (24), 8979, 2022
Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia
HAS El-Nashar, AM Sayed, HAM El-Sherief, ME Rateb, L Akil, I Khadra, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2199950, 2023
Rumex vesicarius L. boosts the effectiveness of sorafenib in triple-negative breast cancer by downregulating BCl2, mTOR, and JNK, and upregulating p21 expression
A Ghanem, MA Ali, MA Elkady, SSA Mageed, MA El Hassab, ...
Pathology-Research and Practice 250, 154807, 2023
Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer
EA Abdelsalam, AA Abd El-Hafeez, WM Eldehna, MA El Hassab, ...
Journal of enzyme inhibition and medicinal chemistry 37 (1), 2265-2282, 2022
Multi-stage structure-based virtual screening approach towards identification of potential SARS-CoV-2 NSP13 helicase inhibitors
MA El Hassab, WM Eldehna, ST Al-Rashood, A Alharbi, RO Eskandrani, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 563-572, 2022
In silico identification of potential SARS COV-2 2′-O-methyltransferase inhibitor: fragment-based screening approach and MM-PBSA calculations
MA El Hassab, TM Ibrahim, AA Shoun, ST Al-Rashood, HM Alkahtani, ...
RSC advances 11 (26), 16026-16033, 2021
Development of 4-((3-oxo-3-phenylpropyl) amino) benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors
MM Elbadawi, WM Eldehna, A Nocentini, WR Somaa, ST Al-Rashood, ...
European Journal of Medicinal Chemistry 238, 114412, 2022
Development of potent nanosized isatin-isonicotinohydrazide hybrid for management of Mycobacterium tuberculosis
WM Eldehna, MA El Hassab, NA Abdelshafi, FAZ Sayed, M Fares, ...
International Journal of Pharmaceutics 612, 121369, 2022
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