A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress O Brandman, J Stewart-Ornstein, D Wong, A Larson, CC Williams, GW Li, ... Cell 151 (5), 1042-1054, 2012 | 697 | 2012 |
Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains PS Shen, J Park, Y Qin, X Li, K Parsawar, MH Larson, J Cox, Y Cheng, ... Science 347 (6217), 75-78, 2015 | 315 | 2015 |
The structure of the polycystic kidney disease channel PKD2 in lipid nanodiscs PS Shen, X Yang, PG DeCaen, X Liu, D Bulkley, DE Clapham, E Cao Cell 167 (3), 763-773. e11, 2016 | 295 | 2016 |
Structure of the Cdc48 segregase in the act of unfolding an authentic substrate I Cooney, H Han, MG Stewart, RH Carson, DT Hansen, JH Iwasa, ... Science 365 (6452), 502-505, 2019 | 164 | 2019 |
Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase N Monroe, H Han, PS Shen, WI Sundquist, CP Hill Elife 6, e24487, 2017 | 141 | 2017 |
Characterization of Pseudomonas chlororaphis myovirus 201ϕ2-1 via genomic sequencing, mass spectrometry, and electron microscopy JA Thomas, MR Rolando, CA Carroll, PS Shen, DM Belnap, ST Weintraub, ... Virology 376 (2), 330-338, 2008 | 123 | 2008 |
Dicer uses distinct modules for recognizing dsRNA termini NK Sinha, J Iwasa, PS Shen, BL Bass Science 359 (6373), 329-334, 2018 | 111 | 2018 |
Vms1p is a release factor for the ribosome-associated quality control complex O Zurita Rendón, EK Fredrickson, CJ Howard, J Van Vranken, S Fogarty, ... Nature communications 9 (1), 2197, 2018 | 109 | 2018 |
The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets H Han, N Monroe, WI Sundquist, PS Shen, CP Hill Elife 6, e31324, 2017 | 101 | 2017 |
The 2017 Nobel Prize in Chemistry: cryo-EM comes of age PS Shen Analytical and bioanalytical chemistry 410, 2053-2057, 2018 | 69 | 2018 |
Structural inhibition of dynamin-mediated membrane fission by endophilin A Hohendahl, N Talledge, V Galli, PS Shen, F Humbert, P De Camilli, ... Elife 6, e26856, 2017 | 48 | 2017 |
Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases H Han, JM Fulcher, VP Dandey, JH Iwasa, WI Sundquist, MS Kay, ... Elife 8, e44071, 2019 | 47 | 2019 |
The structure of avian polyomavirus reveals variably sized capsids, non-conserved inter-capsomere interactions, and a possible location of the minor capsid protein VP4 PS Shen, D Enderlein, CDS Nelson, WS Carter, M Kawano, L Xing, ... Virology 411 (1), 142-152, 2011 | 44 | 2011 |
Sequence and structural characterization of great salt lake bacteriophage CW02, a member of the T7-like supergroup PS Shen, MJ Domek, E Sanz-García, A Makaju, RM Taylor, R Hoggan, ... Journal of virology 86 (15), 7907-7917, 2012 | 43 | 2012 |
Active conformation of the p97-p47 unfoldase complex Y Xu, H Han, I Cooney, Y Guo, NG Moran, NR Zuniga, JC Price, CP Hill, ... Nature communications 13 (1), 2640, 2022 | 26 | 2022 |
Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome MG Rollins, M Shasmal, N Meade, H Astar, PS Shen, D Walsh Cell reports 36 (10), 2021 | 18 | 2021 |
Visualizing the chaperone-mediated folding trajectory of the G protein β5 β-propeller S Wang, MI Sass, Y Kwon, WG Ludlam, TM Smith, EJ Carter, NE Gladden, ... Molecular Cell 83 (21), 3852-3868. e6, 2023 | 7 | 2023 |
Caenorhabditis elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA CD Consalvo, AM Aderounmu, HM Donelick, PJ Aruscavage, DM Eckert, ... Elife 13, RP93979, 2024 | 4* | 2024 |
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97 A Pozner, L Li, SP Verma, S Wang, JJ Barrott, ML Nelson, JSE Yu, ... Nature communications 15 (1), 1165, 2024 | 4 | 2024 |
Elongation of nascent chains PS Shen Science 1, 1, 2015 | 4 | 2015 |