Elsa Garcin
Elsa Garcin
A*MIDEX Excellence Chair, Aix-Marseille University; Adjunct Associate Professor of Biochemistry
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Structure of the [NiFe] Hydrogenase Active Site: Evidence for Biologically Uncommon Fe Ligands⊥
A Volbeda, E Garcin, C Piras, AL de Lacey, VM Fernandez, EC Hatchikian, ...
Journal of the American Chemical Society 118 (51), 12989-12996, 1996
The crystal structure of a reduced [NiFeSe] hydrogenase provides an image of the activated catalytic center
E Garcin, X Vernede, EC Hatchikian, A Volbeda, M Frey, ...
Structure 7 (5), 557-566, 1999
Structural differences between the ready and unready oxidized states of [NiFe] hydrogenases
A Volbeda, L Martin, C Cavazza, M Matho, BW Faber, W Roseboom, ...
JBIC Journal of Biological Inorganic Chemistry 10 (3), 239-249, 2005
Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase
ED Garcin, CM Bruns, SJ Lloyd, DJ Hosfield, M Tiso, R Gachhui, ...
Journal of biological chemistry 279 (36), 37918-37927, 2004
Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase
ED Garcin, AS Arvai, RJ Rosenfeld, MD Kroeger, BR Crane, G Andersson, ...
Nature chemical biology 4 (11), 700-707, 2008
Biphasic coupling of neuronal nitric oxide synthase phosphorylation to the NMDA receptor regulates AMPA receptor trafficking and neuronal cell death
GA Rameau, DS Tukey, ED Garcin-Hosfield, RF Titcombe, C Misra, ...
Journal of Neuroscience 27 (13), 3445-3455, 2007
Halophilic adaptation: novel solvent protein interactions observed in the 2.9 and 2.6 Å resolution structures of the wild type and a mutant of malate dehydrogenase from …
SB Richard, D Madern, E Garcin, G Zaccai
Biochemistry 39 (5), 992-1000, 2000
DNA apurinic-apyrimidinic site binding and excision by endonuclease IV
ED Garcin, DJ Hosfield, SA Desai, BJ Haas, M Björas, RP Cunningham, ...
Nature structural & molecular biology 15 (5), 515, 2008
Hydrogenase: a hydrogen-metabolizing enzyme. What do the crystal structures tell us about its mode of action?
JC Fontecilla-Camps, M Frey, E Garcin, C Hatchikian, Y Montet, C Piras, ...
Biochimie 79 (11), 661-666, 1997
Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency
RJ Rosenfeld, ED Garcin, K Panda, G Andersson, A Åberg, AV Wallace, ...
Biochemistry 41 (47), 13915-13925, 2002
Surface charge interactions of the FMN module govern catalysis by nitric-oxide synthase
K Panda, MM Haque, ED Garcin-Hosfield, D Durra, ED Getzoff, DJ Stuehr
Journal of Biological Chemistry 281 (48), 36819-36827, 2006
The three nitric-oxide synthases differ in their kinetics of tetrahydrobiopterin radical formation, heme-dioxy reduction, and arginine hydroxylation
CC Wei, ZQ Wang, D Durra, C Hemann, R Hille, ED Garcin, ED Getzoff, ...
Journal of Biological Chemistry 280 (10), 8929-8935, 2005
D-Glyceraldehyde-3-Phosphate Dehydrogenase Structure and Function
MR White, ED Garcin
Macromolecular Protein Complexes, 413-453, 2017
A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA
MR White, MM Khan, D Deredge, CR Ross, R Quintyn, BE Zucconi, ...
Journal of Biological Chemistry 290 (3), 1770-1785, 2015
C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase
M Tiso, DW Konas, K Panda, ED Garcin, M Sharma, ED Getzoff, ...
Journal of Biological Chemistry 280 (47), 39208-39219, 2005
GAPDH as a model non-canonical AU-rich RNA binding protein
ED Garcin
Seminars in cell & developmental biology 86, 162-173, 2019
The sweet side of RNA regulation: glyceraldehyde‐3‐phosphate dehydrogenase as a noncanonical RNA‐binding protein
MR White, ED Garcin
Wiley Interdisciplinary Reviews: RNA 7 (1), 53-70, 2016
Interfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity
F Seeger, R Quintyn, A Tanimoto, GJ Williams, JA Tainer, VH Wysocki, ...
Biochemistry 53 (13), 2153-2165, 2014
Small-angle X-ray scattering method to characterize molecular interactions: Proof of concept
N Allec, M Choi, N Yesupriya, B Szychowski, MR White, MG Kann, ...
Scientific reports 5 (1), 1-12, 2015
Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow
NM Rogers, F Seeger, ED Garcin, DD Roberts, JS Isenberg
Frontiers in physiology 5, 134, 2014
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