Luca Gattinoni
Luca Gattinoni
Leibniz Institute for Immunotherapy (LIT)
Verified email at - Homepage
Cited by
Cited by
A human memory T cell subset with stem cell-like properties
L Gattinoni, E Lugli, Y Ji, Z Pos, CM Paulos, MF Quigley, JR Almeida, ...
Nature medicine 17 (10), 1290-1297, 2011
Adoptive immunotherapy for cancer: building on success
L Gattinoni, DJ Powell, SA Rosenberg, NP Restifo
Nature Reviews Immunology 6 (5), 383-393, 2006
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
L Gattinoni, SE Finkelstein, CA Klebanoff, PA Antony, DC Palmer, ...
The Journal of experimental medicine 202 (7), 907-912, 2005
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
CA Klebanoff, L Gattinoni, P Torabi-Parizi, K Kerstann, AR Cardones, ...
Proceedings of the National Academy of Sciences 102 (27), 9571-9576, 2005
Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells
L Gattinoni, CA Klebanoff, DC Palmer, C Wrzesinski, K Kerstann, Z Yu, ...
The Journal of clinical investigation 115 (6), 1616-1626, 2005
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
L Gattinoni, XS Zhong, DC Palmer, Y Ji, CS Hinrichs, Z Yu, C Wrzesinski, ...
Nature medicine 15 (7), 808-813, 2009
Tumor-specific Th17-polarized cells eradicate large established melanoma
P Muranski, A Boni, PA Antony, L Cassard, KR Irvine, A Kaiser, ...
Blood, The Journal of the American Society of Hematology 112 (2), 362-373, 2008
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
M Sukumar, J Liu, Y Ji, M Subramanian, JG Crompton, Z Yu, ...
The Journal of clinical investigation 123 (10), 4479-4488, 2013
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells
CA Klebanoff, SE Finkelstein, DR Surman, MK Lichtman, L Gattinoni, ...
Proceedings of the National Academy of Sciences 101 (7), 1969-1974, 2004
Paths to stemness: building the ultimate antitumour T cell
L Gattinoni, CA Klebanoff, NP Restifo
Nature Reviews Cancer 12 (10), 671-684, 2012
CD8+ T‐cell memory in tumor immunology and immunotherapy
CA Klebanoff, L Gattinoni, NP Restifo
Immunological reviews 211 (1), 214-224, 2006
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling
CM Paulos, C Wrzesinski, A Kaiser, CS Hinrichs, M Chieppa, L Cassard, ...
The Journal of clinical investigation 117 (8), 2197-2204, 2007
IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy
CS Hinrichs, R Spolski, CM Paulos, L Gattinoni, KW Kerstann, DC Palmer, ...
Blood, The Journal of the American Society of Hematology 111 (11), 5326-5333, 2008
The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness
T Wu, Y Ji, EA Moseman, HC Xu, M Manglani, M Kirby, SM Anderson, ...
Science immunology 1 (6), eaai8593, 2016
Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature
P Muranski, ZA Borman, SP Kerkar, CA Klebanoff, Y Ji, L Sanchez-Perez, ...
Immunity 35 (6), 972-985, 2011
Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity
CS Hinrichs, ZA Borman, L Cassard, L Gattinoni, R Spolski, Z Yu, ...
Proceedings of the National Academy of Sciences 106 (41), 17469-17474, 2009
T memory stem cells in health and disease
L Gattinoni, DE Speiser, M Lichterfeld, C Bonini
Nature medicine 23 (1), 18-27, 2017
Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
C Yao, HW Sun, NE Lacey, Y Ji, EA Moseman, HY Shih, EF Heuston, ...
Nature immunology 20 (7), 890-901, 2019
BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis
R Roychoudhuri, K Hirahara, K Mousavi, D Clever, CA Klebanoff, ...
Nature 498 (7455), 506-510, 2013
Superior T memory stem cell persistence supports long-lived T cell memory
E Lugli, MH Dominguez, L Gattinoni, PK Chattopadhyay, DL Bolton, ...
The Journal of clinical investigation 123 (2), 594, 2013
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