| Design, synthesis, docking, and biological evaluation of novel diazide-containing isoxazole-and pyrazole-based histone deacetylase probes R Neelarapu, DL Holzle, S Velaparthi, H Bai, M Brunsteiner, SY Blond, ... Journal of medicinal chemistry 54 (13), 4350-4364, 2011 | 117 | 2011 |
| Photolabile linkers: exploiting labile bond chemistry to control mode and rate of hydrogel degradation and protein release PJ LeValley, R Neelarapu, BP Sutherland, S Dasgupta, CJ Kloxin, ... Journal of the American Chemical Society 142 (10), 4671-4679, 2020 | 59 | 2020 |
| Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors PAP Taha Y. Taha, Shaimaa M. Aboukhatwa, Rachel C. Knopp, Naohiko Ikegaki ... ACS Medicinal Chemistry Letters 8 (8), 824-829, 2017 | 37 | 2017 |
| Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure–Activity and Structure–Property … R Neelarapu, JR Maignan, CL Lichorowic, A Monastyrskyi, TS Mutka, ... Journal of medicinal chemistry 61 (4), 1450-1473, 2018 | 31 | 2018 |
| Novel histone deacetylase 8 ligands without a zinc chelating group: Exploring an ‘upside-down’binding pose AS Vaidya, R Neelarapu, A Madriaga, H Bai, E Mendonca, H Abdelkarim, ... Bioorganic & medicinal chemistry letters 22 (21), 6621-6627, 2012 | 26 | 2012 |
| A carbohydrate-based approach for the total synthesis of strictifolione CV Ramana, N Raghupathi, MK Gurjar, MS Chorghade Tetrahedron letters 46 (23), 4073-4075, 2005 | 25 | 2005 |
| A one-pot selective synthesis of N-Boc protected secondary amines: tandem direct reductive amination/N-Boc protection R Neelarapu, PA Petukhov Tetrahedron 68 (35), 7056-7062, 2012 | 19 | 2012 |
| Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine‐based Histone Deacetylase Inhibitors H Abdelkarim, R Neelarapu, A Madriaga, AS Vaidya, I Kastrati, ... ChemMedChem 12 (24), 2030-2043, 2017 | 13 | 2017 |
| Photoreactive “nanorulers” detect a novel conformation of full length HDAC3-SMRT complex in solution H Abdelkarim, M Brunsteiner, R Neelarapu, H Bai, A Madriaga, ... ACS chemical biology 8 (11), 2538-2549, 2013 | 13 | 2013 |
| A short total synthesis of (+)-cryptocarya diacetate MK Gurjar, N Raghupathi, MS Chorghade Heterocycles 77 (2), 945, 2009 | 8 | 2009 |
| Correction to design, synthesis, and biological evaluation of tetrahydroisoquinoline-based histone deacetylase 8 selective inhibitors TY Taha, SM Aboukhatwa, RC Knopp, N Ikegaki, H Abdelkarim, ... ACS Medicinal Chemistry Letters 10 (9), 1358-1358, 2019 | 3 | 2019 |
| Design, synthesis, and biological evaluation of novel diazide-containing pyrazole-and isoxazole-based HDAC probes R Neelarapu, D Holze, S Velaparthi, H Bai, M Brunsteiner, SY Blond, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 241, 2011 | 2 | 2011 |
| Quinolone-based compounds, formulations, and uses thereof R Manetsch, DE Kyle, R Neelarapu, JR Maignan, CL Lichorowic, ... US Patent 10,000,452, 2018 | | 2018 |
| Optimization of 4 (1H)-quinolone antimalarials for oral bioavailability and in vivo efficacy C Lichorowic, J Maignan, R Neelarapu, A Monastyrski, J Giarrusso, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
| Orally bioavailable and in vivo efficacious antimalarial 4(1H)-quinolones. RM Cynthia Lichorowic, Jordany R. Maignan, Raghupathi Neelarapu, Andrii ... Abstract of Papers of the American Chemical Society 251 (General Poster …, 2016 | | 2016 |
| Synthesis, Antimalarial Activity, and Physicochemical Properties of 7-(2-Phenoxyethoxy)-4 (1H)-quinolones JR Maignan, R Neelarapu, CL Lichorowic, TS Mutka, AN LaCrue, DE Kyle, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |
| Mapping the binding sites of HDAC3/NCoR using photoaffinity chemical probes as molecular rulers. PAP Hazem Abdelkarim, Michael Brunsteiner, Bai He, Raghupathi Neelarapu ... AAPS Annual Meeting and Exposition; McCormick place, Chicago, IL, USA, 2012 | | 2012 |
| The implementation of photoreactive chemical probes in characterizing HDAC3/NCoR complex: a step toward neurodegenerative compatible HDAC inhibitors. PAP Hazem Abdelkarim, Michael Brunsteiner, Raghupathi Neelarapu, Bai He ... The 6th Drug Discovery for Neurodegeneration Conference: An intensive course …, 2012 | | 2012 |
| Exploring a Secondary Binding Site in Histone Deacetylases for Design of Inhibitors lacking Zinc Binding Group AS Vaidya, E Mendonca, H Bai, R Neelarapu, A Madriaga, M Brunsteiner, ... 49th annual MIKI meeting, Lawrence, KS, United States, 2011 | | 2011 |
| Mapping the Binding Sites of HDAC3/NCoR2 Complex using Photoreactive Chemical Probes PAP Hazem Abdelkarim, Michael Brunsteiner, Bai He, Raghupathi Neelarapu ... Abstract of Papers published at 49th annual MIKI meeting, Lawrence, KS …, 2011 | | 2011 |
