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Ahmed Metwaly
Ahmed Metwaly
Associate Professor at faculty of Pharmacy, Al-Azhar University, Cairo, Egypty
Verified email at azhar.edu.eg - Homepage
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Year
Molecular docking and dynamics simulation revealed the potential inhibitory activity of ACEIs against SARS-CoV-2 targeting hACE2 receptor
I Eissa, A Al-Karmalawy, MA Dahab, AM Metwaly, SS Elhady, EB Elkaeed, ...
Frontiers in Chemistry 9, 227, 2021
191*2021
Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4 (3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers
HA Mahdy, MK Ibrahim, AM Metwaly, A Belal, ABM Mehany, ...
Bioorganic Chemistry 94, 103422, 2020
1362020
Traditional ancient Egyptian medicine: A review
AM Metwaly, MM Ghoneim, IH Eissa, IA Elsehemy, AE Mostafa, ...
Saudi journal of biological sciences 28 (10), 5823-5832, 2021
1212021
Black ginseng and its saponins: Preparation, phytochemistry and pharmacological effects
AM Metwaly, Z Lianlian, H Luqi, D Deqiang
Molecules 24 (10), 1856, 2019
1162019
Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors
MK Ibrahim, MS Taghour, AM Metwaly, A Belal, ABM Mehany, ...
European journal of medicinal chemistry 155, 117-134, 2018
1122018
Nigrosphaerin A a new isochromene derivative from the endophytic fungus Nigrospora sphaerica
AM Metwaly, HA Kadry, A Atef, AEI Mohammad, G Ma, SJ Cutler, SA Ross
Phytochemistry letters 7, 1-5, 2014
902014
Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of quinazolin-4(3H)-one derivatives as potential PPARγ and SUR agonists
MK Ibrahim, IH Eissa, MS Alesawy, AM Metwaly, MM Radwan, ...
Bioorganic & medicinal chemistry 25 (17), 4723-4744, 2017
862017
Design, synthesis, docking, DFT, MD simulation studies of a new nicotinamide-based derivative: in vitro anticancer and VEGFR-2 inhibitory effects
EB Elkaeed, RG Yousef, H Elkady, IMM Gobaara, BA Alsfouk, DZ Husein, ...
Molecules 27 (14), 4606, 2022
822022
Comprehensive virtual screening of the antiviral potentialities of marine polycyclic guanidine alkaloids against SARS-CoV-2 (COVID-19)
A El-Demerdash, AM Metwaly, A Hassan, TM Abd El-Aziz, EB Elkaeed, ...
Biomolecules 11 (3), 460, 2021
822021
Design, synthesis, and anti-proliferative evaluation of new quinazolin-4 (3H)-ones as potential VEGFR-2 inhibitors
K El-Adl, AGA El-Helby, RR Ayyad, HA Mahdy, MM Khalifa, HA Elnagar, ...
Bioorganic & Medicinal Chemistry 29, 115872, 2021
792021
Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of novel quinoxaline derivatives as potential PPARγ and SUR agonists
MK Ibrahim, IH Eissa, AE Abdallah, AM Metwaly, MM Radwan, ...
Bioorganic & medicinal chemistry 25 (4), 1496-1513, 2017
792017
Design, molecular docking, in vitro, and in vivo studies of new quinazolin-4 (3H)-ones as VEGFR-2 inhibitors with potential activity against hepatocellular carcinoma
IH Eissa, MK Ibrahim, AM Metwaly, A Belal, ABM Mehany, AA Abdelhady, ...
Bioorganic Chemistry 107, 104532, 2021
772021
Design and synthesis of thiazolidine-2, 4-diones hybrids with 1, 2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: In-vitro anticancer evaluation and in …
MS Taghour, H Elkady, WM Eldehna, NM El-Deeb, AM Kenawy, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1903-1917, 2022
742022
Discovery of new quinazolin-4 (3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation
IH Eissa, AGA El-Helby, HA Mahdy, MM Khalifa, HA Elnagar, ...
Bioorganic Chemistry 105, 104380, 2020
722020
New combination approaches to combat methicillin-resistant Staphylococcus aureus (MRSA)
MH Sharaf, GM El-Sherbiny, SA Moghannem, M Abdelmonem, ...
Scientific reports 11 (1), 4240, 2021
712021
Discovery of new anticancer thiourea-azetidine hybrids: Design, synthesis, in vitro antiproliferative, SAR, in silico molecular docking against VEGFR-2, ADMET, toxicity, and …
DR Parmar, JY Soni, R Guduru, RH Rayani, RV Kusurkar, AG Vala, ...
Bioorganic Chemistry 115, 105206, 2021
692021
Discovery of new quinoxaline-2 (1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation
K El-Adl, HM Sakr, RG Yousef, ABM Mehany, AM Metwaly, ...
Bioorganic Chemistry 114, 105105, 2021
682021
Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors
IH Eissa, AM Metwaly, A Belal, ABM Mehany, RR Ayyad, K El‐Adl, ...
Archiv der Pharmazie 352 (11), 1900123, 2019
662019
New quinoxaline-2 (1H)-ones as potential VEGFR-2 inhibitors: Design, synthesis, molecular docking, ADMET profile and anti-proliferative evaluations
R Yousef, H Sakr, I Eissa, A Mehany, A Metwaly, MA Elhendawy, ...
New Journal of Chemistry, 2021
632021
Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II …
AGA El-Helby, H Sakr, RR Ayyad, HA Mahdy, MM Khalifa, A Belal, ...
Bioorganic chemistry 103, 104233, 2020
632020
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