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Mathieu Coutu
Mathieu Coutu
Verified email at umontreal.ca
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Year
Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity
M Veillette, A Désormeaux, H Medjahed, NE Gharsallah, M Coutu, ...
Journal of virology 88 (5), 2633-2644, 2014
2752014
The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals
M Veillette, M Coutu, J Richard, LA Batraville, O Dagher, N Bernard, ...
Journal of virology 89 (1), 545-551, 2015
1882015
Flow cytometry-based assay to study HIV-1 gp120 specific antibody-dependent cellular cytotoxicity responses
J Richard, M Veillette, LA Batraville, M Coutu, JP Chapleau, M Bonsignori, ...
Journal of virological methods 208, 107-114, 2014
762014
Small CD4 mimetics prevent HIV-1 uninfected bystander CD4+ T cell killing mediated by antibody-dependent cell-mediated cytotoxicity
J Richard, M Veillette, S Ding, D Zoubchenok, N Alsahafi, M Coutu, ...
EBioMedicine 3, 122-134, 2016
752016
A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies
S Ding, M Veillette, M Coutu, J Prévost, L Scharf, PJ Bjorkman, G Ferrari, ...
Journal of Virology 90 (4), 2127-2134, 2016
682016
Co-receptor binding site antibodies enable CD4-mimetics to expose conserved anti-cluster A ADCC epitopes on HIV-1 envelope glycoproteins
J Richard, B Pacheco, N Gohain, M Veillette, S Ding, N Alsahafi, ...
EBioMedicine 12, 208-218, 2016
652016
The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions
A Désormeaux, M Coutu, H Medjahed, B Pacheco, A Herschhorn, C Gu, ...
Journal of virology 87 (5), 2549-2562, 2013
612013
Influence of the envelope gp120 Phe 43 cavity on HIV-1 sensitivity to antibody-dependent cell-mediated cytotoxicity responses
J Prévost, D Zoubchenok, J Richard, M Veillette, B Pacheco, M Coutu, ...
Journal of virology 91 (7), 10.1128/jvi. 02452-16, 2017
552017
Conformational evaluation of HIV-1 trimeric envelope glycoproteins using a cell-based ELISA assay
M Veillette, M Coutu, J Richard, LA Batraville, A Désormeaux, M Roger, ...
JoVE (Journal of Visualized Experiments), e51995, 2014
482014
BST-2 expression modulates small CD4-mimetic sensitization of HIV-1-infected cells to antibody-dependent cellular cytotoxicity
J Richard, J Prévost, B von Bredow, S Ding, N Brassard, H Medjahed, ...
Journal of virology 91 (11), 10.1128/jvi. 00219-17, 2017
462017
Impaired downregulation of NKG2D ligands by Nef proteins from elite controllers sensitizes HIV-1-infected cells to antibody-dependent cellular cytotoxicity
N Alsahafi, J Richard, J Prévost, M Coutu, N Brassard, MS Parsons, ...
Journal of Virology 91 (16), 10.1128/jvi. 00109-17, 2017
362017
A highly conserved gp120 inner domain residue modulates Env conformation and trimer stability
S Ding, WD Tolbert, J Prévost, B Pacheco, M Coutu, O Debbeche, ...
Journal of virology 90 (19), 8395-8409, 2016
232016
HIV-1 gp120 dimers decrease the overall affinity of gp120 preparations for CD4-induced ligands
M Coutu, A Finzi
Journal of virological methods 215, 37-44, 2015
232015
HIV-1 gp120 envelope glycoprotein determinants for cytokine burst in human monocytes
B Levast, L Barblu, M Coutu, J Prévost, N Brassard, A Peres, C Stegen, ...
PloS one 12 (3), e0174550, 2017
162017
A Highly Conserved Residue in HIV-1 Nef Alpha Helix 2 Modulates Protein Expression
AL Johnson, BS Dirk, M Coutu, SMM Haeryfar, EJ Arts, A Finzi, ...
mSphere 1 (6), e00288-16, 2016
122016
Lineage-specific differences between the gp120 inner domain layer 3 of human immunodeficiency virus and that of simian immunodeficiency virus
S Ding, H Medjahed, J Prévost, M Coutu, SH Xiang, A Finzi
Journal of virology 90 (22), 10065-10073, 2016
72016
A highly-conserved residue of the HIV-1-gp120 inner domain is important for ADCC responses mediated by anti-cluster A antibodies
S Ding, M Veillete, M Coutu, J Prévost, L Scharf, PJ Bjorkman, G Ferrari, ...
Journal of Virology 90 (4), 2127-2134, 2016
52016
HIV-1 Entry and Fusion Inhibitors: Mechanisms and Resistance
CM Venner, AN Ratcliff, M Coutu, A Finzi, EJ Arts
Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, Volume 1, 545-557, 2017
32017
The HIV-1 gp120 CD4-bound conformation is preferentially targeted by ADCC-mediating antibodies in sera from HIV-1-infected individuals.
M Veillette, M Coutu, J Richard, LA Batraville, O Dagher, N Bernard, ...
Journal of virology, JVI. 02868-14, 2014
22014
Étude du rôle des régions variables 4 et 5 dans les changements de conformation de la gp120 du VIH-1
M Coutu
2016
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