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Fabrice Gielen
Fabrice Gielen
Verified email at exeter.ac.uk
Title
Cited by
Cited by
Year
Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics
PY Colin, B Kintses, F Gielen, CM Miton, G Fischer, MF Mohamed, ...
Nature communications 6 (1), 10008, 2015
3902015
Ultrahigh-throughput–directed enzyme evolution by absorbance-activated droplet sorting (AADS)
F Gielen, R Hours, S Emond, M Fischlechner, U Schell, F Hollfelder
Proceedings of the National Academy of Sciences 113 (47), E7383-E7389, 2016
2552016
A microdroplet dilutor for high-throughput screening
X Niu, F Gielen, JB Edel, AJ Demello
Nature chemistry 3 (6), 437-442, 2011
2402011
Exploring sequence space in search of functional enzymes using microfluidic droplets
P Mair, F Gielen, F Hollfelder
Current Opinion in Chemical Biology 37, 137-144, 2017
1122017
Electro-coalescence of digitally controlled droplets
X Niu, F Gielen, AJ demello, JB Edel
Analytical chemistry 81 (17), 7321-7325, 2009
1092009
A fully unsupervised compartment-on-demand platform for precise nanoliter assays of time-dependent steady-state enzyme kinetics and inhibition
F Gielen, L van Vliet, BT Koprowski, SRA Devenish, M Fischlechner, ...
Analytical chemistry 85 (9), 4761-4769, 2013
1042013
Deep learning guided image-based droplet sorting for on-demand selection and analysis of single cells and 3D cell cultures
V Anagnostidis, B Sherlock, J Metz, P Mair, F Hollfelder, F Gielen
Lab on a Chip 20 (5), 889-900, 2020
732020
Interfacing microwells with nanoliter compartments: a sampler generating high-resolution concentration gradients for quantitative biochemical analyses in droplets
F Gielen, T Buryska, LV Vliet, M Butz, J Damborsky, Z Prokop, F Hollfelder
Analytical chemistry 87 (1), 624-632, 2015
522015
Materials and methods for droplet microfluidic device fabrication
KS Elvira, F Gielen, SSH Tsai, AM Nightingale
Lab on a Chip 22 (5), 859-875, 2022
372022
Long‐term perfusion culture of monoclonal embryonic stem cells in 3D hydrogel beads for continuous optical analysis of differentiation
H Kleine‐Brüggeney, LD Van Vliet, C Mulas, F Gielen, CC Agley, ...
Small 15 (5), 1804576, 2019
332019
Quantitative affinity determination by fluorescence anisotropy measurements of individual nanoliter droplets
F Gielen, M Butz, EJ Rees, M Erdelyi, T Moschetti, M Hyvönen, JB Edel, ...
Analytical chemistry 89 (2), 1092-1101, 2017
252017
A method to quantify FRET stoichiometry with phasor plot analysis and acceptor lifetime ingrowth
WY Chen, E Avezov, SC Schlachter, F Gielen, RF Laine, HP Harding, ...
Biophysical journal 108 (5), 999-1002, 2015
242015
High-resolution local imaging of temperature in dielectrophoretic platforms
F Gielen, F Pereira, AJ Demello, JB Edel
Analytical chemistry 82 (17), 7509-7514, 2010
222010
Dielectric cell response in highly conductive buffers
F Gielen, AJ deMello, JB Edel
Analytical Chemistry 84 (4), 1849-1853, 2012
202012
Multi‐Object detector yolov4‐tiny enables high‐throughput combinatorial and spatially‐resolved sorting of cells in microdroplets
L Howell, V Anagnostidis, F Gielen
Advanced Materials Technologies 7 (5), 2101053, 2022
192022
Controlled oil/water partitioning of hydrophobic substrates extending the bioanalytical applications of droplet-based microfluidics
T Buryska, M Vasina, F Gielen, P Vanacek, L van Vliet, J Jezek, Z Pilat, ...
Analytical chemistry 91 (15), 10008-10015, 2019
192019
Ultrahigh-throughput screening of single-cell lysates for directed evolution and functional metagenomics
F Gielen, PY Colin, P Mair, F Hollfelder
Protein engineering: methods and protocols, 297-309, 2018
182018
Phenotyping single-cell motility in microfluidic confinement
SA Bentley, H Laeverenz-Schlogelhofer, V Anagnostidis, J Cammann, ...
Elife 11, e76519, 2022
142022
Increasing the trapping efficiency of particles in microfluidic planar platforms by means of negative dielectrophoresis
F Gielen, AJ demello, T Cass, JB Edel
The Journal of Physical Chemistry B 113 (5), 1493-1500, 2009
122009
Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats
LH Lindenburg, T Pantelejevs, F Gielen, P Zuazua-Villar, M Butz, E Rees, ...
Proceedings of the National Academy of Sciences 118 (46), e2017708118, 2021
102021
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Articles 1–20