| Intrinsically disordered protein AK Dunker, JD Lawson, CJ Brown, RM Williams, P Romero, JS Oh, ... Journal of molecular graphics and modelling 19 (1), 26-59, 2001 | 2891 | 2001 |
| Intrinsic disorder and protein function AK Dunker, CJ Brown, JD Lawson, LM Iakoucheva, Z Obradović Biochemistry 41 (21), 6573-6582, 2002 | 2137 | 2002 |
| Intrinsic disorder in cell-signaling and cancer-associated proteins LM Iakoucheva, CJ Brown, JD Lawson, Z Obradović, AK Dunker Journal of molecular biology 323 (3), 573-584, 2002 | 1449 | 2002 |
| Acquired Resistance to KRASG12C Inhibition in Cancer MM Awad, S Liu, II Rybkin, KC Arbour, J Dilly, VW Zhu, ML Johnson, ... New England Journal of Medicine 384 (25), 2382-2393, 2021 | 679 | 2021 |
| Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12D Inhibitor X Wang, S Allen, JF Blake, V Bowcut, DM Briere, A Calinisan, JR Dahlke, ... Journal of medicinal chemistry 65 (4), 3123-3133, 2021 | 413 | 2021 |
| Protein flexibility and intrinsic disorder P Radivojac, Z Obradovic, DK Smith, G Zhu, S Vucetic, CJ Brown, ... Protein Science 13 (1), 71-80, 2004 | 408 | 2004 |
| DisProt: a database of protein disorder S Vucetic, Z Obradovic, V Vacic, P Radivojac, K Peng, LM Iakoucheva, ... Bioinformatics 21 (1), 137-140, 2005 | 289 | 2005 |
| Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor J Hallin, V Bowcut, A Calinisan, DM Briere, L Hargis, LD Engstrom, ... Nature medicine 28 (10), 2171-2182, 2022 | 228 | 2022 |
| Is myosin a" back door" enzyme? RG Yount, D Lawson, I Rayment Biophysical journal 68 (4 Suppl), 44S, 1995 | 196 | 1995 |
| Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP-Deleted Cancers CR Smith, R Aranda, TP Bobinski, DM Briere, AC Burns, JG Christensen, ... Journal of Medicinal Chemistry 65 (3), 1749-1766, 2022 | 77 | 2022 |
| Fragment-based discovery of a small molecule inhibitor of Bruton’s tyrosine kinase CR Smith, DR Dougan, M Komandla, T Kanouni, B Knight, JD Lawson, ... Journal of Medicinal Chemistry 58 (14), 5437-5444, 2015 | 75 | 2015 |
| Molecular dynamics analysis of structural factors influencing back door pi release in myosin JD Lawson, E Pate, I Rayment, RG Yount Biophysical journal 86 (6), 3794-3803, 2004 | 66 | 2004 |
| Design and discovery of MRTX0902, a potent, selective, brain-penetrant, and orally bioavailable inhibitor of the SOS1: KRAS protein–protein interaction JM Ketcham, J Haling, S Khare, V Bowcut, DM Briere, AC Burns, RJ Gunn, ... Journal of Medicinal Chemistry 65 (14), 9678-9690, 2022 | 54 | 2022 |
| Structural model of the regulatory domain of smooth muscle heavy meromyosin JL Wahlstrom, MA Randall, JD Lawson, DE Lyons, WF Siems, GJ Crouch, ... Journal of Biological Chemistry 278 (7), 5123-5131, 2003 | 41 | 2003 |
| A back-to-front fragment-based drug design search strategy targeting the DFG-out pocket of protein tyrosine kinases H Iwata, H Oki, K Okada, T Takagi, M Tawada, Y Miyazaki, S Imamura, ... ACS medicinal chemistry letters 3 (4), 342-346, 2012 | 33 | 2012 |
| MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer LD Engstrom, R Aranda, L Waters, K Moya, V Bowcut, L Vegar, D Trinh, ... Cancer discovery 13 (11), 2412-2431, 2023 | 32 | 2023 |
| Fragment-based drug discovery of potent and selective MKK3/6 inhibitors M Adams, T Kobayashi, JD Lawson, M Saitoh, K Shimokawa, SV Bigi, ... Bioorganic & medicinal chemistry letters 26 (3), 1086-1089, 2016 | 26 | 2016 |
| Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 2 C McBride, Z Cheruvallath, M Komandla, M Tang, P Farrell, JD Lawson, ... Bioorganic & Medicinal Chemistry Letters 26 (12), 2779-2783, 2016 | 25 | 2016 |
| Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1 Z Cheruvallath, M Tang, C McBride, M Komandla, J Miura, T Ton-Nu, ... Bioorganic & medicinal chemistry letters 26 (12), 2774-2778, 2016 | 22 | 2016 |
| Isolation of chloroform-resistant mutants of filamentous phage: localization in models of phage structure JS Oh, DR Davies, JD Lawson, GE Arnold, AK Dunker Journal of molecular biology 287 (3), 449-457, 1999 | 21 | 1999 |
