Accurate prediction of protein structures and interactions using a three-track neural network M Baek, F DiMaio, I Anishchenko, J Dauparas, S Ovchinnikov, GR Lee, ... Science 373 (6557), 871-876, 2021 | 3457 | 2021 |
The goblet cell-derived mediator RELM-β drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis V Morampudi, U Dalwadi, G Bhinder, HP Sham, SK Gill, J Chan, ... Mucosal immunology 9 (5), 1218-1233, 2016 | 103 | 2016 |
Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses G Bhinder, M Stahl, HP Sham, SM Crowley, V Morampudi, U Dalwadi, ... Infection and immunity 82 (9), 3753-3763, 2014 | 81 | 2014 |
Molecular architecture of the yeast Elongator complex reveals an unexpected asymmetric subunit arrangement DT Setiaputra, DTH Cheng, S Lu, JM Hansen, U Dalwadi, CHY Lam, ... EMBO reports 18 (2), 280-291, 2017 | 45 | 2017 |
Structural insights into the function of Elongator U Dalwadi, CK Yip Cellular and Molecular Life Sciences 75, 1613-1622, 2018 | 35 | 2018 |
Tricellular tight junction protein tricellulin is targeted by the enteropathogenic Escherichia coli effector EspG1, leading to epithelial barrier disruption V Morampudi, FA Graef, M Stahl, U Dalwadi, VS Conlin, T Huang, ... Infection and immunity 85 (1), 10.1128/iai. 00700-16, 2017 | 29 | 2017 |
Probing the architecture, dynamics, and inhibition of the PI4KIIIα/TTC7/FAM126 complex GL Dornan, U Dalwadi, DJ Hamelin, RM Hoffmann, CK Yip, JE Burke Journal of molecular biology 430 (18), 3129-3142, 2018 | 28 | 2018 |
Molecular architecture of the essential yeast histone acetyltransferase complex NuA4 redefines its multimodularity D Setiaputra, S Ahmad, U Dalwadi, AL Steunou, S Lu, JD Ross, MQ Dong, ... Molecular and cellular biology 38 (9), e00570-17, 2018 | 28 | 2018 |
Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation MK Rathinaswamy, U Dalwadi, KD Fleming, C Adams, JTB Stariha, ... Science Advances 7 (35), eabj4282, 2021 | 24 | 2021 |
The substrate specificity of the human TRAPPII complex’s Rab-guanine nucleotide exchange factor activity ML Jenkins, NJ Harris, U Dalwadi, KD Fleming, DS Ziemianowicz, ... Communications Biology 3 (1), 735, 2020 | 19 | 2020 |
Vasoactive intestinal peptide prevents PKCε-induced intestinal epithelial barrier disruption during EPEC infection V Morampudi, VS Conlin, U Dalwadi, X Wu, KC Marshall, C Nguyen, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (5 …, 2015 | 19 | 2015 |
Biochemical insight into novel Rab-GEF activity of the mammalian TRAPPIII complex NJ Harris, ML Jenkins, U Dalwadi, KD Fleming, SE Nam, MAH Parson, ... Journal of Molecular Biology 433 (18), 167145, 2021 | 12 | 2021 |
Transmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cells CH Kerr, U Dalwadi, NE Scott, CK Yip, LJ Foster, E Jan Scientific Reports 8 (1), 17353, 2018 | 11 | 2018 |
HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases MK Rathinaswamy, KD Fleming, U Dalwadi, E Pardon, NJ Harris, CK Yip, ... Structure 29 (12), 1371-1381. e6, 2021 | 9 | 2021 |
Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs MK Rathinaswamy, ML Jenkins, BR Duewell, X Zhang, NJ Harris, ... Cell Reports 42 (3), 2023 | 6 | 2023 |
Biochemical characterization of the TINTIN module of the NuA4 complex reveals allosteric regulation of nucleosome interaction U Dalwadi, E Corrado, KD Fleming, BE Moeller, SE Nam, JE Burke, ... Molecular and Cellular Biology 42 (11), e00170-22, 2022 | 3 | 2022 |
Biochemical and structural characterization of human core elongator and its subassemblies U Dalwadi, D Mannar, F Zierhut, CK Yip ACS omega 7 (4), 3424-3433, 2022 | 3 | 2022 |
Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain NJ Harris, ML Jenkins, SE Nam, MK Rathinaswamy, MAH Parson, ... Elife 12, RP88058, 2023 | 1 | 2023 |
Data for EMSL Project 51616 from November 2021 C Yip, U Dalwadi, D Vasyliuk Pacific Northwest National Lab.(PNNL), Richland, WA (United States …, 2021 | | 2021 |
Biochemical and structural characterization of the Elongator, TINTIN, and PI3K gamma complexes U Dalwadi University of British Columbia, 2021 | | 2021 |