| Design, synthesis, molecular docking, and anticancer activity of benzoxazole derivatives as VEGFR‐2 inhibitors AGA El‐Helby, H Sakr, IH Eissa, H Abulkhair, AA Al‐Karmalawy, K El‐Adl Archiv der Pharmazie 352 (10), 1900113, 2019 | 119 | 2019 |
| Telaprevir is a potential drug for repurposing against SARS-CoV-2: computational and in vitro studies A Mahmoud, A Mostafa, AA Al-Karmalawy, A Zidan, HS Abulkhair, ... Heliyon 7 (9), 2021 | 68 | 2021 |
| Computational insights on the potential of some NSAIDs for treating COVID-19: priority set and lead optimization A Abo Elmaaty, MIA Hamed, MI Ismail, E B. Elkaeed, H S. Abulkhair, ... Molecules 26 (12), 3772, 2021 | 67 | 2021 |
| Discovery of new quinoxaline-2 (1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation K El-Adl, HM Sakr, RG Yousef, ABM Mehany, AM Metwaly, ... Bioorganic Chemistry 114, 105105, 2021 | 62 | 2021 |
| New quinoxaline-2 (1 H)-ones as potential VEGFR-2 inhibitors: Design, synthesis, molecular docking, ADMET profile and anti-proliferative evaluations RG Yousef, HM Sakr, IH Eissa, ABM Mehany, AM Metwaly, ... New Journal of Chemistry 45 (36), 16949-16964, 2021 | 61 | 2021 |
| From triazolophthalazines to triazoloquinazolines: A bioisosterism-guided approach toward the identification of novel PCAF inhibitors with potential anticancer activity MH El-Shershaby, A Ghiaty, AH Bayoumi, AA Al-Karmalawy, ... Bioorganic & Medicinal Chemistry 42, 116266, 2021 | 55 | 2021 |
| β-Blockers bearing hydroxyethylamine and hydroxyethylene as potential SARS-CoV-2 Mpro inhibitors: Rational based design, in silico, in vitro, and SAR studies for lead optimization MIA Hamed, KM Darwish, R Soltane, A Chrouda, A Mostafa, NMA Shama, ... RSC advances 11 (56), 35536-35558, 2021 | 51 | 2021 |
| Design, synthesis, in silico ADMET profile and GABA‐A docking of novel phthalazines as potent anticonvulsants AGA El‐Helby, RRA Ayyad, MF Zayed, HS Abulkhair, H Elkady, K El‐Adl Archiv Der Pharmazie 352 (5), 1800387, 2019 | 49 | 2019 |
| Arylthiazole antibiotics targeting intracellular methicillin-resistant Staphylococcus aureus (MRSA) that interfere with bacterial cell wall synthesis I Eid, MM Elsebaei, H Mohammad, M Hagras, CE Peters, YA Hegazy, ... European journal of medicinal chemistry 139, 665-673, 2017 | 49 | 2017 |
| The antimicrobial potential and pharmacokinetic profiles of novel quinoline-based scaffolds: synthesis and in silico mechanistic studies as dual DNA gyrase and DHFR inhibitors MH El-Shershaby, KM El-Gamal, AH Bayoumi, K El-Adl, M Alswah, ... New Journal of Chemistry 45 (31), 13986-14004, 2021 | 48 | 2021 |
| Design, synthesis, molecular docking, anticancer evaluations, and in silico pharmacokinetic studies of novel 5‐[(4‐chloro/2, 4‐dichloro) benzylidene] thiazolidine‐2, 4‐dione … K El‐Adl, AGA El‐Helby, H Sakr, RR Ayyad, HA Mahdy, M Nasser, ... Archiv der Pharmazie 354 (2), 2000279, 2021 | 47 | 2021 |
| Unravelling the anticancer potency of 1,2,4-triazole-N-arylamide hybrids through inhibition of STAT3: synthesis and in silico mechanistic studies A Turky, AH Bayoumi, FF Sherbiny, K El-Adl, HS Abulkhair Molecular diversity 25, 403-420, 2021 | 45 | 2021 |
| Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1, 2, 3-triazole-chalcone conjugates EM Othman, EA Fayed, EM Husseiny, HS Abulkhair Bioorganic Chemistry 123, 105762, 2022 | 43 | 2022 |
| Pharmacophore‐linked pyrazolo[3,4‐d]pyrimidines as EGFR‐TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies AA Gaber, AM El‐Morsy, FF Sherbiny, AH Bayoumi, KM El‐Gamal, ... Archiv Der Pharmazie, e2100258, 2021 | 43 | 2021 |
| In vitro and computational investigations of novel synthetic carboxamide-linked pyridopyrrolopyrimidines with potent activity as SARS-CoV-2-M Pro inhibitors A Aljuhani, HEA Ahmed, SK Ihmaid, AM Omar, SS Althagfan, ... RSC advances 12 (41), 26895-26907, 2022 | 42 | 2022 |
| Synthesis and antibacterial evaluation of a novel library of 2-(thiazol-5-yl)-1, 3, 4-oxadiazole derivatives against methicillin-resistant Staphylococcus aureus (MRSA) MH Hannoun, M Hagras, A Kotb, AAMM El-Attar, HS Abulkhair Bioorganic chemistry 94, 103364, 2020 | 42 | 2020 |
| 1, 2, 4-Triazolo [4, 3-c] quinazolines: a bioisosterism-guided approach towards the development of novel PCAF inhibitors with potential anticancer activity MH El-Shershaby, A Ghiaty, AH Bayoumi, HEA Ahmed, MS El-Zoghbi, ... New Journal of Chemistry 45 (25), 11136-11152, 2021 | 40 | 2021 |
| Synthesis, structural characterization, DFT calculations, molecular docking, and molecular dynamics simulations of a novel ferrocene derivative to unravel its potential … MM Hammoud, M Khattab, M Abdel-Motaal, J Van der Eycken, R Alnajjar, ... Journal of Biomolecular Structure and Dynamics 41 (11), 5199-5216, 2023 | 39 | 2023 |
| Novel triazolophthalazine-hydrazone hybrids as potential PCAF inhibitors: Design, synthesis, in vitro anticancer evaluation, apoptosis, and molecular docking studies HS Abulkhair, A Turky, A Ghiaty, HEA Ahmed, AH Bayoumi Bioorganic Chemistry 100, 103899, 2020 | 39 | 2020 |
| Design, synthesis, and antitumor activity of novel compounds based on 1, 2, 4-triazolophthalazine scaffold: apoptosis-inductive and PCAF-inhibitory effects A Turky, AH Bayoumi, A Ghiaty, AS El-Azab, AM Alaa, HS Abulkhair Bioorganic Chemistry 101, 104019, 2020 | 37 | 2020 |
Khaled El-AdlProfessorVerified email at Azhar.edu.eg
