Per I Arvidsson
Per I Arvidsson
Director, Science for Life Laboratory, Karolinska Institute, Sweden & Research Professor Univ. of
Verified email at - Homepage
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The outstanding biological stability of β‐and γ‐peptides toward proteolytic enzymes: an in vitro investigation with fifteen peptidases
J Frackenpohl, PI Arvidsson, JV Schreiber, D Seebach
ChemBioChem 2 (6), 445-455, 2001
Rational design of asymmetric organocatalysts––increased reactivity and solvent scope with a tetrazolic acid
A Hartikka, PI Arvidsson
Tetrahedron: Asymmetry 15 (12), 1831-1834, 2004
Mechanistic insights into the phosphine-free RuCp*-diamine-catalyzed hydrogenation of aryl ketones: Experimental and theoretical evidence for an alcohol-mediated dihydrogen …
C Hedberg, K Källström, PI Arvidsson, P Brandt, PG Andersson
Journal of the American Chemical Society 127 (43), 15083-15090, 2005
Organocatalytic synthesis of chiral benzopyrans
T Govender, L Hojabri, FM Moghaddam, PI Arvidsson
Tetrahedron: Asymmetry 17 (12), 1763-1767, 2006
On the Antimicrobial and Hemolytic Activities of Amphiphilic β‐Peptides
PI Arvidsson, J Frackenpohl, NS Ryder, B Liechty, F Petersen, ...
ChemBioChem 2 (10), 771-773, 2001
Antibiotic and hemolytic activity of a β2/β3 peptide capable of folding into a 12/10‐helical secondary structure
PI Arvidsson, NS Ryder, HM Weiss, G Gross, O Kretz, R Woessner, ...
ChemBioChem 4 (12), 1345-1347, 2003
The outstanding metabolic stability of a 14C‐labeled β‐nonapeptide in rats – in vitro and in vivo pharmacokinetic studies
H Wiegand, B Wirz, A Schweitzer, GP Camenisch, MI Rodriguez Perez, ...
Biopharmaceutics & drug disposition 23 (6), 251-262, 2002
Design, machine synthesis, and NMR-solution structure of a β-heptapeptide forming a salt-bridge stabilised 314-helix in methanol and in waterElectronic supplementary …
PI Arvidsson, M Rueping, D Seebach
Chemical Communications, 649-650, 2001
Sulfonimidamides in medicinal and agricultural chemistry
PK Chinthakindi, T Naicker, N Thota, T Govender, HG Kruger, ...
Angewandte Chemie International Edition 56 (15), 4100-4109, 2017
Tetrazolic acid functionalized dihydroindol: rational design of a highly selective cyclopropanation organocatalyst
A Hartikka, PI Arvidsson
The Journal of Organic Chemistry 72 (15), 5874-5877, 2007
Linear, Peptidase‐Resistant β2/β3‐Di‐and α/β3‐Tetrapeptide Derivatives with Nanomolar Affinities to a Human Somatostatin Receptor, Preliminary Communication
D Seebach, M Rueping, PI Arvidsson, T Kimmerlin, P Micuch, C Noti, ...
Helvetica Chimica Acta 84 (11), 3503-3510, 2001
Novel Imidazo [4, 5-b] Pyridine Derivatives as Inhibitors of Glycogen Synthase Kinase 3 for Use in the Treatment of Dementia and Neurodegenerative Disorders
PI Arvidsson, E Arzel, J Burrows, M Claesson, C Ray, T Rein, D Rotticci, ...
US Patent App. 12/089,002, 2008
AZD 1080, a novel GSK 3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans
B Georgievska, J Sandin, J Doherty, A Mörtberg, J Neelissen, ...
Journal of neurochemistry 125 (3), 446-456, 2013
A new imidazole‐containing imidazolidinone catalyst for organocatalyzed asymmetric conjugate addition of nitroalkanes to aldehydes
L Hojabri, A Hartikka, FM Moghaddam, PI Arvidsson
Advanced Synthesis & Catalysis 349 (4‐5), 740-748, 2007
Enantioselective organocatalyzed transformations of β-ketoesters
T Govender, PI Arvidsson, GEM Maguire, HG Kruger, T Naicker
Chemical Reviews 116 (16), 9375-9437, 2016
Exploring the Antibacterial and Hemolytic Activity of Shorter‐ and Longer‐Chain β‐, α,β‐, and γ‐Peptides, and of β‐Peptides from β2‐3‐Aza‐ and β3‐2 …
PI Arvidsson, NS Ryder, HM Weiss, DF Hook, J Escalante, D Seebach
Chemistry & biodiversity 2 (3), 401-420, 2005
Syntheses and CD‐Spectroscopic Investigations of Longer‐Chain β‐Peptides: Preparation by Solid‐Phase Couplings of Single Amino Acids, Dipeptides, and …
PI Arvidsson, J Frackenpohl, D Seebach
Helvetica chimica acta 86 (5), 1522-1553, 2003
5‐(Pyrrolidine‐2‐yl) tetrazole: rationale for the increased reactivity of the tetrazole analogue of proline in organocatalyzed aldol reactions
A Hartikka, PI Arvidsson
European journal of organic chemistry 2005 (20), 4287-4295, 2005
Intraaggregate Fluxional Lithium and Carbanion Exchanges in a Chiral Lithium Amide/n‐Butyllithium Mixed Tetramer Directly Observed by Multinuclear NMR
PI Arvidsson, P Ahlberg, G Hilmersson
Chemistry–A European Journal 5 (4), 1348-1354, 1999
A synthesis of “dual warhead” β-aryl ethenesulfonyl fluorides and one-pot reaction to β-sultams
PK Chinthakindi, KB Govender, AS Kumar, HG Kruger, T Govender, ...
Organic Letters 19 (3), 480-483, 2017
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