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Karen A. Ryall
Karen A. Ryall
Guardant Health
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Year
Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
RC Laker, JC Drake, RJ Wilson, VA Lira, BM Lewellen, KA Ryall, ...
Nature communications 8 (1), 548, 2017
3912017
DSigDB: drug signatures database for gene set analysis
M Yoo, J Shin, J Kim, KA Ryall, K Lee, S Lee, M Jeon, J Kang, AC Tan
Bioinformatics 31 (18), 3069-3071, 2015
3332015
A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo
RC Laker, P Xu, KA Ryall, A Sujkowski, BM Kenwood, KH Chain, ...
Journal of Biological Chemistry 289 (17), 12005-12015, 2014
2282014
Systems biology approaches for advancing the discovery of effective drug combinations
KA Ryall, AC Tan
Journal of cheminformatics 7, 1-15, 2015
1432015
Repeated traumatic brain injury affects composite cognitive function in piglets
SH Friess, RN Ichord, J Ralston, K Ryall, MA Helfaer, C Smith, ...
Journal of neurotrauma 26 (7), 1111-1121, 2009
1262009
Network reconstruction and systems analysis of cardiac myocyte hypertrophy signaling
KA Ryall, DO Holland, KA Delaney, MJ Kraeutler, AJ Parker, ...
Journal of Biological Chemistry 287 (50), 42259-42268, 2012
892012
Dual targeting of PDGFRα and FGFR1 displays synergistic efficacy in malignant rhabdoid tumors
JP Wong, JR Todd, MA Finetti, F McCarthy, M Broncel, S Vyse, ...
Cell reports 17 (5), 1265-1275, 2016
522016
Automated image analysis identifies signaling pathways regulating distinct signatures of cardiac myocyte hypertrophy
GT Bass, KA Ryall, A Katikapalli, BE Taylor, ST Dang, ST Acton, ...
Journal of molecular and cellular cardiology 52 (5), 923-930, 2012
492012
Folic acid enhances early functional recovery in a piglet model of pediatric head injury
MY Naim, S Friess, C Smith, J Ralston, K Ryall, MA Helfaer, SS Margulies
Developmental neuroscience 32 (5-6), 466-479, 2011
492011
Phenotypic screen quantifying differential regulation of cardiac myocyte hypertrophy identifies CITED4 regulation of myocyte elongation
KA Ryall, VJ Bezzerides, A Rosenzweig, JJ Saucerman
Journal of molecular and cellular cardiology 72, 74-84, 2014
452014
Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer
JR Todd, KA Ryall, S Vyse, JP Wong, RC Natrajan, Y Yuan, AC Tan, ...
Oncotarget 7 (39), 62939, 2016
372016
In situ deformations in the immature brain during rapid rotations
NG Ibrahim, R Natesh, SE Szczesny, K Ryall, SA Eucker, B Coats, ...
312010
Atg2, Atg9 and Atg18 in mitochondrial integrity, cardiac function and healthspan in Drosophila
P Xu, D Damschroder, M Zhang, KA Ryall, PN Adler, JJ Saucerman, ...
Journal of molecular and cellular cardiology 127, 116-124, 2019
302019
Simulated driving performance among daily and occasional cannabis users
A Brooks-Russell, T Brown, K Friedman, J Wrobel, J Schwarz, G Dooley, ...
Accident Analysis & Prevention 160, 106326, 2021
272021
PD-L1 immunostaining scoring for non-small cell lung cancer based on immunosurveillance parameters
MA Silva, KA Ryall, C Wilm, J Caldara, HJ Grote, JC Patterson-Kane
PLoS One 13 (6), e0196464, 2018
272018
Automated imaging reveals a concentration dependent delay in reversibility of cardiac myocyte hypertrophy
KA Ryall, JJ Saucerman
Journal of Molecular and Cellular Cardiology 53 (2), 282-290, 2012
252012
Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy. Nat Commun. 2017; 8 (1): 548
RC Laker, JC Drake, RJ Wilson, VA Lira, BM Lewellen, KA Ryall, ...
Epub 2017/09/17. PubMed PMID: 28916822, 0
22
Efficacy and molecular mechanisms of differentiated response to the Aurora and angiogenic kinase inhibitor ENMD-2076 in preclinical models of p53-mutated triple-negative breast …
AA Ionkina, JJ Tentler, J Kim, A Capasso, TM Pitts, KA Ryall, RR Howison, ...
Frontiers in Oncology 7, 94, 2017
202017
An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer
KA Ryall, J Kim, PJ Klauck, J Shin, M Yoo, A Ionkina, TM Pitts, JJ Tentler, ...
BMC genomics 16, 1-10, 2015
122015
Expanding the computational toolbox for interrogating cancer kinomes
AC Tan, KA Ryall, PH Huang
Pharmacogenomics 17 (2), 95-97, 2016
32016
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