Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines SG Patel, EJ Sayers, L He, R Narayan, TL Williams, EM Mills, ... Scientific Reports 9 (1), 6298, 2019 | 142 | 2019 |
Mechanistic studies on norcoclaurine synthase of benzylisoquinoline alkaloid biosynthesis: an enzymatic Pictet− Spengler reaction LYP Luk, S Bunn, DK Liscombe, PJ Facchini, ME Tanner Biochemistry 46 (35), 10153-10161, 2007 | 137 | 2007 |
Unraveling the role of protein dynamics in dihydrofolate reductase catalysis LYP Luk, J Javier Ruiz-Pernia, WM Dawson, M Roca, EJ Loveridge, ... Proceedings of the National Academy of Sciences 110 (41), 16344-16349, 2013 | 136 | 2013 |
A cope rearrangement in the reaction catalyzed by dimethylallyltryptophan synthase? LYP Luk, Q Qian, ME Tanner Journal of the American Chemical Society 133 (32), 12342-12345, 2011 | 85 | 2011 |
Mechanism of dimethylallyltryptophan synthase: evidence for a dimethylallyl cation intermediate in an aromatic prenyltransferase reaction LYP Luk, ME Tanner Journal of the American Chemical Society 131 (39), 13932-13933, 2009 | 73 | 2009 |
Using genetically incorporated unnatural amino acids to control protein functions in mammalian cells AR Nödling, LA Spear, TL Williams, LYP Luk, YH Tsai Essays in biochemistry 63 (2), 237-266, 2019 | 67 | 2019 |
Increased Dynamic Effects in a Catalytically Compromised Variant of Escherichia coli Dihydrofolate Reductase JJ Ruiz-Pernia, LYP Luk, R García-Meseguer, S Martí, EJ Loveridge, ... Journal of the American Chemical Society 135 (49), 18689-18696, 2013 | 63 | 2013 |
Protein motions and dynamic effects in enzyme catalysis LYP Luk, EJ Loveridge, RK Allemann Physical Chemistry Chemical Physics 17 (46), 30817-30827, 2015 | 51 | 2015 |
Condensation of 2-((alkylthio)(aryl) methylene) malononitrile with 1, 2-aminothiol as a novel bioorthogonal reaction for site-specific protein modification and peptide cyclization X Zheng, Z Li, W Gao, X Meng, X Li, LYP Luk, Y Zhao, YH Tsai, C Wu Journal of the American Chemical Society 142 (11), 5097-5103, 2020 | 37 | 2020 |
Reactivity and selectivity of iminium organocatalysis improved by a protein host AR Nödling, K Świderek, R Castillo, JW Hall, A Angelastro, LC Morrill, ... Angewandte Chemie 130 (38), 12658-12662, 2018 | 36 | 2018 |
Comparative biological evaluation and G-quadruplex interaction studies of two new families of organometallic gold (I) complexes featuring N-heterocyclic carbene and alkynyl ligands SM Meier-Menches, B Aikman, D Döllerer, WT Klooster, SJ Coles, N Santi, ... Journal of Inorganic Biochemistry 202, 110844, 2020 | 35 | 2020 |
Chemical ligation and isotope labeling to locate dynamic effects during catalysis by dihydrofolate reductase LYP Luk, JJ Ruiz‐Pernía, AS Adesina, EJ Loveridge, I Tuñón, V Moliner, ... Angewandte Chemie 127 (31), 9144-9148, 2015 | 35 | 2015 |
Protein Isotope Effects in Dihydrofolate Reductase From Geobacillus stearothermophilus Show Entropic–Enthalpic Compensatory Effects on the Rate Constant LYP Luk, JJ Ruiz-Pernía, WM Dawson, EJ Loveridge, I Tuñón, V Moliner, ... Journal of the American Chemical Society 136 (49), 17317-17323, 2014 | 33 | 2014 |
A Versatile Disulfide-Driven Recycling System for NADP+ with High Cofactor Turnover Number A Angelastro, WM Dawson, LYP Luk, RK Allemann ACS Catalysis 7 (2), 1025-1029, 2017 | 30 | 2017 |
Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases LYP Luk, EJ Loveridge, RK Allemann Journal of the American Chemical Society 136 (19), 6862-6865, 2014 | 29 | 2014 |
Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes AR Nödling, EM Mills, X Li, D Cardella, EJ Sayers, SH Wu, AT Jones, ... Chemical Communications 56 (34), 4672-4675, 2020 | 28 | 2020 |
Minimization of dynamic effects in the evolution of dihydrofolate reductase JJ Ruiz-Pernía, E Behiry, LYP Luk, EJ Loveridge, I Tunón, V Moliner, ... Chemical Science 7 (5), 3248-3255, 2016 | 26 | 2016 |
Thermal Adaptation of Dihydrofolate Reductase from the Moderate Thermophile Geobacillus stearothermophilus J Guo, LYP Luk, EJ Loveridge, RK Allemann Biochemistry 53 (17), 2855-2863, 2014 | 25 | 2014 |
Use of an asparaginyl endopeptidase for chemo-enzymatic peptide and protein labeling TMS Tang, D Cardella, AJ Lander, X Li, JS Escudero, YH Tsai, LYP Luk Chemical Science 11 (23), 5881-5888, 2020 | 23 | 2020 |
Site-specific His/Asp phosphoproteomic analysis of prokaryotes reveals putative targets for drug resistance SJ Lai, IF Tu, WL Wu, JT Yang, LYP Luk, MC Lai, YH Tsai, SH Wu BMC microbiology 17 (1), 1-10, 2017 | 22 | 2017 |