Three-dimensional and chemical mapping of intracellular signaling nanodomains in health and disease with enhanced expansion microscopy TMD Sheard, ME Hurley, J Colyer, E White, R Norman, E Pervolaraki, ... ACS nano 13 (2), 2143-2157, 2019 | 48 | 2019 |
A correlative super-resolution protocol to visualise structural underpinnings of fast second-messenger signalling in primary cell types ME Hurley, TMD Sheard, R Norman, HM Kirton, SS Shah, E Pervolaraki, ... Methods 193, 27-37, 2021 | 12 | 2021 |
3D ultrastructural organisation of calcium release units in the avian sarcoplasmic reticulum TMD Sheard, SR Kharche, C Pinali, HA Shiels Journal of Experimental Biology 222 (7), jeb197640, 2019 | 12 | 2019 |
Three-dimensional visualization of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads TMD Sheard, ME Hurley, AJ Smith, J Colyer, E White, I Jayasinghe Philosophical Transactions of the Royal Society B 377 (1864), 20210316, 2022 | 8 | 2022 |
Enhanced expansion microscopy to measure nanoscale structural and biochemical remodeling in single cells TMD Sheard, I Jayasinghe Methods in Cell Biology 161, 147-180, 2021 | 7 | 2021 |
Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics M Holmes, ME Hurley, TMD Sheard, AP Benson, I Jayasinghe, ... Philosophical Transactions of the Royal Society B 377 (1864), 20210317, 2022 | 5 | 2022 |
Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease ME Hurley, E White, TMD Sheard, D Steele, I Jayasinghe Open Biology 13 (5), 230045, 2023 | 4 | 2023 |
Expansion microscopy reveals subdomains in C. elegans germ granules KM Suen, TMD Sheard, CC Lin, D Milonaityte, I Jayasinghe, JE Ladbury Life Science Alliance 6 (4), 2023 | 3 | 2023 |
Differential labelling of human sub-cellular compartments with fluorescent dye esters and expansion microscopy TMD Sheard, TB Shakespeare, RS Seehra, ME Spencer, KM Suen, ... Nanoscale 15 (45), 18489-18499, 2023 | 3 | 2023 |
Geometry-preserving expansion microscopy microplates enable high-fidelity nanoscale distortion mapping RS Seehra, SJ Warrington, BHK Allouis, TMD Sheard, ME Spencer, ... Cell Reports Physical Science 4 (12), 2023 | 2 | 2023 |
Molecular-scale 3D visualisation of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads TMD Sheard, ME Hurley, AJ Smith, J Colyer, E White, I Jayasinghe BioRxiv, 2021.10. 21.462365, 2021 | 1 | 2021 |
Visualization of angiotensin II type 1 receptors in their native cellular organization by using expansion microscopy YDLMZ Diaz, TMD Sheard, CB Andersen, I Jayasinghe, EA Christensen Biophysical Journal 123 (3), 464a, 2024 | | 2024 |
Super-Resolution Analysis of the Origins of the Elementary Events of ER Calcium Release in Dorsal Root Ganglion Neurons ME Hurley, SS Shah, TMD Sheard, HM Kirton, DS Steele, N Gamper, ... Cells 13 (1), 38, 2023 | | 2023 |
Correction: Expansion microscopy reveals subdomains in C. elegans germ granules KM Suen, TMD Sheard, CC Lin, D Milonaityte, I Jayasinghe, JE Ladbury Life Science Alliance 7 (1), e202302405-e202302405, 2023 | | 2023 |
Diverse labelling of cellular compartments with NHS esters in expansion microscopy TMD Sheard, ME Spencer, T Shakespeare, RS Seehra, KM Suen, ... Biophysical Journal 122 (3), 275a, 2023 | | 2023 |
Angiotensin II Treatment Induces Reorganization and Changes in the Lateral Dynamics of Angiotensin II Type 1 Receptor in the Plasma Membrane Elucidated by Photoactivated … C Andersen, YM Zulueta Díaz, JL Kure, M Hessellund Eriksen, AL Lovatt, ... Analytical Chemistry 95 (2), 730-738, 2022 | | 2022 |
Correlative super-resolution microscopy of intracellular calcium release channels and fast, cytoplasmic calcium signals M Hurley, T Sheard, E White, D Steele, I Jayasinghe ACTA PHYSIOLOGICA 236, 27-27, 2022 | | 2022 |
Molecular-scale analysis of cardiac calcium nanodomains and remodelling using expansion microscopy TMD Sheard University of Leeds, 2021 | | 2021 |
A super-resolution protocol to correlate structural underpinnings of fast second-messenger signalling in primary cell types ME Hurley, TMD Sheard, R Norman, HM Kirton, SS Shah, E Pervolaraki, ... bioRxiv, 2020.09. 29.319400, 2020 | | 2020 |
Peptide ligands of the cardiac ryanodine receptor as super-resolution imaging probes TMD Sheard, L Howlett, H Kirton, Z Yang, G Gurrola, D Steele, ... bioRxiv, 2020.06. 26.131854, 2020 | | 2020 |