Ahmed Hassan Abdelazeem
Ahmed Hassan Abdelazeem
Professor of Medicinal Chemistry & Drug Design, Faculty of Pharmacy, Beni-Suef University, Egypt
Verified email at pharm.bsu.edu.eg - Homepage
Title
Cited by
Cited by
Year
Synthesis, anticancer activity and molecular modeling studies of 1, 2, 4-triazole derivatives as EGFR inhibitors
HAM El-Sherief, BGM Youssif, SNA Bukhari, AH Abdelazeem, ...
European journal of medicinal chemistry 156, 774-789, 2018
732018
Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents
AH Abdelazeem, SA Abdelatef, MT El-Saadi, HA Omar, SI Khan, ...
European Journal of Pharmaceutical Sciences 62, 197-211, 2014
602014
Design, synthesis and pharmacological evaluation of novel pyrrolizine derivatives as potential anticancer agents
AM Gouda, AH Abdelazeem, ESA Arafa, KRA Abdellatif
Bioorganic chemistry 53, 1-7, 2014
362014
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance
GF Zha, HL Qin, BGM Youssif, MW Amjad, MAG Raja, AH Abdelazeem, ...
European journal of medicinal chemistry 135, 34-48, 2017
342017
Design, synthesis and biological evaluation of novel diphenylthiazole-based cyclooxygenase inhibitors as potential anticancer agents
AH Abdelazeem, AM Gouda, HA Omar, MF Tolba
Bioorganic chemistry 57, 132-141, 2014
342014
OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro
AA El-shaimaa, AH Abdelazeem, HH Arab, HA Omar
Acta Pharmacologica Sinica 35 (3), 394-400, 2014
332014
Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino [1, 2-a] indol-1 (2H)-ones as potential anticancer …
BGM Youssif, MH Abdelrahman, AH Abdelazeem, HM Ibrahim, OIA Salem, ...
European journal of medicinal chemistry 146, 260-273, 2018
322018
Synthesis, Biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory …
MH Abdelrahman, BGM Youssif, AH Abdelazeem, HM Ibrahim, ...
European journal of medicinal chemistry 127, 972-985, 2017
312017
Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards selective COX-1 inhibitors with better gastric profile
AH Abdelazeem, MT El-Saadi, AGS El-Din, HA Omar, SM El-Moghazy
Bioorganic & medicinal chemistry 25 (2), 665-676, 2017
282017
Design, synthesis and anticancer evaluation of novel spirobenzo [h] chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities
SA Abdelatef, MT El-Saadi, NH Amin, AH Abdelazeem, HA Omar, ...
European journal of medicinal chemistry 150, 567-578, 2018
272018
Novel diphenylthiazole derivatives with multi-target mechanism: Synthesis, docking study, anticancer and anti-inflammatory activities
AH Abdelazeem, MT El-Saadi, EG Said, BGM Youssif, HA Omar, ...
Bioorganic chemistry 75, 127-138, 2017
262017
Synthesis and pharmacological characterization of a novel sigma receptor ligand with improved metabolic stability and antagonistic effects against methamphetamine
MJ Seminerio, MJ Robson, AH Abdelazeem, C Mesangeau, ...
The AAPS journal 14 (1), 43-51, 2012
262012
Design, synthesis, and biological evaluation of some novel pyrrolizine derivatives as COX inhibitors with anti-inflammatory/analgesic activities and low ulcerogenic liability
AM Gouda, HI Ali, WH Almalki, MA Azim, MAS Abourehab, ...
Molecules 21 (2), 201, 2016
252016
An integrated overview on pyrrolizines as potential anti-inflammatory, analgesic and antipyretic agents
AM Gouda, AH Abdelazeem
European journal of medicinal chemistry 114, 257-292, 2016
242016
Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents
AH Abdelazeem, SI Khan, SW White, KJ Sufka, CR McCurdy
Bioorganic & medicinal chemistry 23 (13), 3248-3259, 2015
242015
Blockade of Cocaine or Sigma Receptor Agonist Self-Administration by Subtype- Selective Sigma Receptor Antagonists
CRMC Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice ...
Journal of Pharmacology and Experimental Therapeutics, 2016
212016
Pyrrolizines: design, synthesis, anticancer evaluation and investigation of the potential mechanism of action
AM Gouda, AH Abdelazeem, HA Omar, AN Abdalla, MAS Abourehab, ...
Bioorganic & medicinal chemistry 25 (20), 5637-5651, 2017
172017
Design, Synthesis, and Anti‐Inflammatory Evaluation of Novel Diphenylthiazole–Thiazolidinone Hybrids
AH Abdelazeem, SA Salama, IA Maghrabi
Archiv der Pharmazie 348 (7), 518-530, 2015
162015
Ligand-based modeling followed by in vitro bioassay yielded new potent glucokinase activators
MO Taha, M Habash, MH Ma’mon, AH Abdelazeem, A Qandil
Journal of Molecular Graphics and Modelling 56, 91-102, 2015
162015
Pyrrolizine-5-carboxamides: Exploring the impact of various substituents on the anti-inflammatory and anticancer activities
AM Gouda, AH Abdelazeem, AN Abdalla, M Ahmed
Acta Pharmaceutica 68 (3), 251-273, 2018
152018
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