Nikken Wiradharma
Nikken Wiradharma
Karp Lab @ Harvard-MIT Health Science and Technology (HST)
Verified email at
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Emerging trends in macromolecular antimicrobials to fight multi-drug-resistant infections
AC Engler, N Wiradharma, ZY Ong, DJ Coady, JL Hedrick, YY Yang
Nano Today 7 (3), 201-222, 2012
Strategies employed in the design and optimization of synthetic antimicrobial peptide amphiphiles with enhanced therapeutic potentials
ZY Ong, N Wiradharma, YY Yang
Advanced drug delivery reviews 78, 28-45, 2014
Self-assembled oligopeptide nanostructures for co-delivery of drug and gene with synergistic therapeutic effect
N Wiradharma, YW Tong, YY Yang
Biomaterials 30 (17), 3100-3109, 2009
Bio-functional micelles self-assembled from a folate-conjugated block copolymer for targeted intracellular delivery of anticancer drugs
SQ Liu, N Wiradharma, SJ Gao, YW Tong, YY Yang
Biomaterials 28 (7), 1423-1433, 2007
Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents
N Wiradharma, U Khoe, CAE Hauser, SV Seow, S Zhang, YY Yang
Biomaterials 32 (8), 2204-2212, 2011
Self-assembled polymer nanostructures for delivery of anticancer therapeutics
N Wiradharma, Y Zhang, S Venkataraman, JL Hedrick, YY Yang
Nano Today 4 (4), 302-317, 2009
Synthesis of a family of amphiphilic glycopolymers via controlled ring-opening polymerization of functionalized cyclic carbonates and their application in drug delivery
F Suriano, R Pratt, JPK Tan, N Wiradharma, A Nelson, YY Yang, P Dubois, ...
Biomaterials 31 (9), 2637-2645, 2010
Advanced Materials for Co‐Delivery of Drugs and Genes in Cancer Therapy
M Khan, ZY Ong, N Wiradharma, ABE Attia, YY Yang
Advanced healthcare materials 1 (4), 373-392, 2012
Cationic micelles self-assembled from cholesterol-conjugated oligopeptides as an efficient gene delivery vector
XD Guo, F Tandiono, N Wiradharma, D Khor, CG Tan, M Khan, Y Qian, ...
Biomaterials 29 (36), 4838-4846, 2008
Broad-Spectrum Antimicrobial Supramolecular Assemblies with Distinctive Size and Shape
K Fukushima, JPK Tan, PA Korevaar, YY Yang, J Pitera, A Nelson, ...
ACS nano 6 (10), 9191-9199, 2012
Supramolecular high-aspect ratio assemblies with strong antifungal activity
K Fukushima, S Liu, H Wu, AC Engler, DJ Coady, H Maune, J Pitera, ...
Nature Communications 4 (1), 2861, 2013
Prodrugs as self-assembled hydrogels: a new paradigm for biomaterials
PK Vemula, N Wiradharma, JA Ankrum, OR Miranda, G John, JM Karp
Current opinion in biotechnology 24 (6), 1174-1182, 2013
The effect of thiol functional group incorporation into cationic helical peptides on antimicrobial activities and spectra
N Wiradharma, M Khan, LK Yong, CAE Hauser, SV Seow, S Zhang, ...
Biomaterials 32 (34), 9100-9108, 2011
Self‐assembled Cationic Peptide Nanoparticles Capable of Inducing Efficient Gene Expression In Vitro
N Wiradharma, M Khan, YW Tong, S Wang, YY Yang
Advanced Functional Materials 18 (6), 943-951, 2008
Rationally Designed α‐Helical Broad‐Spectrum Antimicrobial Peptides with Idealized Facial Amphiphilicity
N Wiradharma, M Sng, M Khan, ZY Ong, YY Yang
Macromolecular Rapid Communications 34 (1), 74-80, 2013
Delivery of reprogramming factors into fibroblasts for generation of non-genetic induced pluripotent stem cells using a cationic bolaamphiphile as a non-viral vector
M Khan, K Narayanan, H Lu, Y Choo, C Du, N Wiradharma, YY Yang, ...
Biomaterials 34 (21), 5336-5343, 2013
Synthetic β-sheet forming peptide amphiphiles for treatment of fungal keratitis
H Wu, ZY Ong, S Liu, Y Li, N Wiradharma, YY Yang, JY Ying
Biomaterials 43, 44-49, 2015
Diaminododecane-based cationic bolaamphiphile as a non-viral gene delivery carrier
M Khan, CY Ang, N Wiradharma, LK Yong, S Liu, L Liu, S Gao, YY Yang
Biomaterials 33 (18), 4673-4680, 2012
Cationic amphiphilic alpha-helical peptides for the treatment of carbapenem-resistant Acinetobacter baumannii infection
Y Huang, N Wiradharma, K Xu, Z Ji, S Bi, L Li, YY Yang, W Fan
Biomaterials 33 (34), 8841-8847, 2012
Design and Evaluation of Peptide Amphiphiles with Different Hydrophobic Blocks for Simultaneous Delivery of Drugs and Genes
N Wiradharma, YW Tong, YY Yang
Macromolecular rapid communications 31 (13), 1212-1217, 2010
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