Michael D.W. Griffin
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Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax
J Gruszczyk, U Kanjee, LJ Chan, S Menant, B Malleret, NTY Lim, ...
Science 359 (6371), 48-55, 2018
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ...
Nature communications 9 (1), 2422, 2018
Small heat-shock proteins prevent α-synuclein aggregation via transient interactions and their efficacy is affected by the rate of aggregation
D Cox, E Selig, MDW Griffin, JA Carver, H Ecroyd
Journal of Biological Chemistry 291 (43), 22618-22629, 2016
Methionine oxidation induces amyloid fibril formation by full-length apolipoprotein AI
YQ Wong, KJ Binger, GJ Howlett, MDW Griffin
Proceedings of the National Academy of Sciences 107 (5), 1977-1982, 2010
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen
BR Burgess, RCJ Dobson, MF Bailey, SC Atkinson, MDW Griffin, ...
Journal of Biological Chemistry 283 (41), 27598-27603, 2008
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance
RCJ Dobson, MDW Griffin, GB Jameson, JA Gerrard
Acta Crystallographica Section D: Biological Crystallography 61 (8), 1116-1124, 2005
Evolution of quaternary structure in a homotetrameric enzyme
MDW Griffin, RCJ Dobson, FG Pearce, L Antonio, AE Whitten, CK Liew, ...
Journal of Molecular Biology 380 (4), 691-703, 2008
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis
G Kefala, GL Evans, MDW Griffin, SRA Devenish, FG Pearce, MA Perugini, ...
Biochemical Journal 411 (2), 351-360, 2008
Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways
MDW Griffin, MLY Mok, LM Wilson, CLL Pham, LJ Waddington, ...
Journal of molecular biology 375 (1), 240-256, 2008
Structural understanding of interleukin 6 family cytokine signaling and targeted therapies: focus on interleukin 11
RD Metcalfe, TL Putoczki, MDW Griffin
Frontiers in Immunology 11, 1424, 2020
A novel ultra-stable, monomeric green fluorescent protein for direct volumetric imaging of whole organs using CLARITY
DJ Scott, NJ Gunn, KJ Yong, VC Wimmer, NA Veldhuis, LM Challis, ...
Scientific reports 8 (1), 667, 2018
The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis
KA Davies, MC Tanzer, MDW Griffin, YF Mok, SN Young, R Qin, EJ Petrie, ...
Cell Death & Differentiation 25 (9), 1567-1580, 2018
Apolipoproteins and amyloid fibril formation in atherosclerosis
CL Teoh, MDW Griffin, GJ Howlett
Protein & cell 2 (2), 116-127, 2011
Loss of NF-κB1 causes gastric cancer with aberrant inflammation and expression of immune checkpoint regulators in a STAT-1-dependent manner
LA O’Reilly, TL Putoczki, LA Mielke, JT Low, A Lin, A Preaudet, MJ Herold, ...
Immunity 48 (3), 570-583. e8, 2018
A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis
LM Wilson, YF Mok, KJ Binger, MDW Griffin, HDT Mertens, F Lin, ...
Journal of molecular biology 366 (5), 1639-1651, 2007
Emerging roles for the IL-6 family of cytokines in pancreatic cancer
G van Duijneveldt, MDW Griffin, TL Putoczki
Clinical Science 134 (16), 2091-2115, 2020
Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate
RCJ Dobson, MDW Griffin, SJ Roberts, JA Gerrard
Biochimie 86 (4-5), 311-315, 2004
Biochemical and structural insights into doublecortin-like kinase domain 1
O Patel, W Dai, M Mentzel, MDW Griffin, J Serindoux, Y Gay, S Fischer, ...
Structure 24 (9), 1550-1561, 2016
The structure of human interleukin-11 reveals receptor-binding site features and structural differences from interleukin-6
TL Putoczki, RCJ Dobson, MDW Griffin
Acta Crystallographica Section D: Biological Crystallography 70 (9), 2277-2285, 2014
Avoiding the oligomeric state: αB‐crystallin inhibits fragmentation and induces dissociation of apolipoprotein C‐II amyloid fibrils
KJ Binger, H Ecroyd, S Yang, JA Carver, GJ Howlett, MDW Griffin
The FASEB journal 27 (3), 1214-1222, 2013
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