Adam McCluskey
Adam McCluskey
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Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition
L Von Kleist, W Stahlschmidt, H Bulut, K Gromova, D Puchkov, ...
Cell 146 (3), 471-484, 2011
Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells
MT Howes, M Kirkham, J Riches, K Cortese, PJ Walser, F Simpson, ...
Journal of Cell Biology 190 (4), 675-691, 2010
Serine− threonine protein phosphatase inhibitors: Development of potential therapeutic strategies
A McCluskey, ATR Sim, JA Sakoff
Journal of medicinal chemistry 45 (6), 1151-1175, 2002
Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis
A McCluskey, JA Daniel, G Hadzic, N Chau, EL Clayton, A Mariana, ...
Traffic 14 (12), 1272-1289, 2013
Activity and thermal stability of lysozyme in alkylammonium formate ionic liquids—influence of cation modification
JP Mann, A McCluskey, R Atkin
Green Chemistry 11 (6), 785-792, 2009
Inhibition of Dynamin Mediated Endocytosis by the DynolesSynthesis and Functional Activity of a Family of Indoles
TA Hill, CP Gordon, AB McGeachie, B Venn-Brown, LR Odell, N Chau, ...
Journal of medicinal chemistry 52 (12), 3762-3773, 2009
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells
JR Stehn, NK Haass, T Bonello, M Desouza, G Kottyan, H Treutlein, ...
Cancer research 73 (16), 5169-5182, 2013
‘Green’leaching: recyclable and selective leaching of gold-bearing ore in an ionic liquid
JA Whitehead, GA Lawrance, A McCluskey
Green Chemistry 6 (7), 313-315, 2004
Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism
CB Harper, S Martin, TH Nguyen, SJ Daniels, NA Lavidis, MR Popoff, ...
Journal of Biological Chemistry 286 (41), 35966-35976, 2011
Modified norcantharidins: synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity
ME Hart, AR Chamberlin, C Walkom, JA Sakoff, A McCluskey
Bioorganic & medicinal chemistry letters 14 (8), 1969-1973, 2004
Application of 1-alkyl-3-methyl-imidazolium ionic liquids in the oxidative leaching of sulphidic copper, gold and silver ores
JA Whitehead, J Zhang, N Pereira, A McCluskey, GA Lawrance
Hydrometallurgy 88 (1-4), 109-120, 2007
Cantharidin analogues: synthesis and evaluation of growth inhibition in a panel of selected tumour cell lines
A McCluskey, SP Ackland, MC Bowyer, ML Baldwin, J Garner, ...
Bioorganic chemistry 31 (1), 68-79, 2003
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief
DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ...
Science translational medicine 9 (392), eaal3447, 2017
Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues
JA Sakoff, SP Ackland, ML Baldwin, MA Keane, A McCluskey
Investigational new drugs 20 (1), 1-11, 2002
Anhydride modified cantharidin analogues: synthesis, inhibition of protein phosphatases 1 and 2A and anticancer activity
A McCluskey, MC Bowyer, E Collins, ATR Sim, JA Sakoff, ML Baldwin
Bioorganic & medicinal chemistry letters 10 (15), 1687-1690, 2000
Molecularly imprinted polymers (MIPs): sensing, an explosive new opportunity?
A McCluskey, CI Holdsworth, MC Bowyer
Organic & Biomolecular Chemistry 5 (20), 3233-3244, 2007
Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A
A McCluskey, C Walkom, MC Bowyer, SP Ackland, E Gardiner, JA Sakoff
Bioorganic & medicinal chemistry letters 11 (22), 2941-2946, 2001
The expanding utility of continuous flow hydrogenation
PJ Cossar, L Hizartzidis, MI Simone, A McCluskey, CP Gordon
Organic & Biomolecular Chemistry 13 (26), 7119-7130, 2015
Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation
TA Hill, SG Stewart, SP Ackland, J Gilbert, B Sauer, JA Sakoff, ...
Bioorganic & medicinal chemistry 15 (18), 6126-6134, 2007
Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I …
A Quan, AB McGeachie, DJ Keating, EM Van Dam, J Rusak, N Chau, ...
Molecular pharmacology 72 (6), 1425-1439, 2007
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