Thymus size and age-related thymic involution: early programming, sexual dimorphism, progenitors and stroma J Gui, LM Mustachio, DM Su, RW Craig Aging and disease 3 (3), 280, 2012 | 267 | 2012 |
Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers M Kawakami, LM Mustachio, L Zheng, Y Chen, J Rodriguez-Canales, ... Proceedings of the National Academy of Sciences 115 (8), 1913-1918, 2018 | 81 | 2018 |
Targeting KRAS in Cancer: Promising Therapeutic Strategies LM Mustachio, A Chelariu-Raicu, L Szekvolgyi, J Roszik Cancers 13 (6), 1204, 2021 | 48 | 2021 |
Next-generation CDK2/9 inhibitors and anaphase catastrophe in lung cancer M Kawakami, LM Mustachio, J Rodriguez-Canales, B Mino, J Roszik, ... JNCI: Journal of the National Cancer Institute 109 (6), djw297, 2017 | 47 | 2017 |
CDK2 inhibition causes anaphase catastrophe in lung cancer through the centrosomal protein CP110 S Hu, AV Danilov, K Godek, B Orr, LJ Tafe, J Rodriguez-Canales, ... Cancer research 75 (10), 2029-2038, 2015 | 44 | 2015 |
The ISG15-specific protease USP18 regulates stability of PTEN LM Mustachio, M Kawakami, Y Lu, J Rodriguez-Canales, B Mino, ... Oncotarget 8 (1), 3, 2017 | 42 | 2017 |
Dinaciclib induces anaphase catastrophe in lung cancer cells via inhibition of cyclin-dependent kinases 1 and 2 AV Danilov, S Hu, B Orr, K Godek, LM Mustachio, D Sekula, X Liu, ... Molecular cancer therapeutics 15 (11), 2758-2766, 2016 | 39 | 2016 |
Evidence for the ISG15-specific deubiquitinase USP18 as an antineoplastic target LM Mustachio, Y Lu, M Kawakami, J Roszik, SJ Freemantle, X Liu, ... Cancer research 78 (3), 587-592, 2018 | 37 | 2018 |
Deubiquitinase USP18 loss mislocalizes and destabilizes KRAS in lung cancer LM Mustachio, Y Lu, LJ Tafe, V Memoli, J Rodriguez-Canales, B Mino, ... Molecular Cancer Research 15 (7), 905-914, 2017 | 35 | 2017 |
Repression of GCN5 expression or activity attenuates c-MYC expression in non-small cell lung cancer LM Mustachio, J Roszik, AT Farria, K Guerra, SYR Dent American Journal of Cancer Research 9 (8), 1830, 2019 | 34 | 2019 |
Tyrosine threonine kinase inhibition eliminates lung cancers by augmenting apoptosis and polyploidy L Zheng, Z Chen, M Kawakami, Y Chen, J Roszik, LM Mustachio, ... Molecular cancer therapeutics 18 (10), 1775-1786, 2019 | 33 | 2019 |
The Vibrio cholerae mannitol transporter is regulated posttranscriptionally by the MtlS small regulatory RNA LM Mustachio, S Aksit, RH Mistry, R Scheffler, A Yamada, JM Liu Journal of bacteriology 194 (3), 598-606, 2012 | 32 | 2012 |
The ubiquitin-specific peptidase USP18 promotes lipolysis, fatty acid oxidation, and lung cancer growth X Liu, Y Lu, Z Chen, X Liu, W Hu, L Zheng, Y Chen, JM Kurie, M Shi, ... Molecular Cancer Research 19 (4), 667-677, 2021 | 24 | 2021 |
GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways AT Farria, LM Mustachio, ZHC Akdemir, SYR Dent Oncotarget 10 (56), 5847, 2019 | 23 | 2019 |
Specific CP110 phosphorylation sites mediate anaphase catastrophe after CDK2 inhibition: evidence for cooperation with USP33 knockdown S Hu, Y Lu, B Orr, K Godek, LM Mustachio, M Kawakami, D Sekula, ... Molecular cancer therapeutics 14 (11), 2576-2585, 2015 | 23 | 2015 |
Current targeted therapies for the fight against non-small cell lung cancer LM Mustachio, J Roszik Pharmaceuticals 13 (11), 374, 2020 | 22 | 2020 |
Targeting the SAGA and ATAC transcriptional coactivator complexes in MYC-driven cancers LM Mustachio, J Roszik, A Farria, SYR Dent Cancer research 80 (10), 1905-1911, 2020 | 20 | 2020 |
Engaging anaphase catastrophe mechanisms to eradicate aneuploid cancers M Kawakami, LM Mustachio, X Liu, E Dmitrovsky Molecular cancer therapeutics 17 (4), 724-731, 2018 | 18 | 2018 |
Single-cell sequencing: current applications in precision onco-genomics and cancer therapeutics LM Mustachio, J Roszik Cancers 14 (3), 657, 2022 | 15 | 2022 |
A novel CDK2/9 inhibitor CYC065 causes anaphase catastrophe and represses proliferation, tumorigenesis, and metastasis in aneuploid cancers M Kawakami, LM Mustachio, Y Chen, Z Chen, X Liu, CH Wei, J Roszik, ... Molecular cancer therapeutics 20 (3), 477-489, 2021 | 10 | 2021 |