Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: implications for oxygen sensing and hypoxic signaling in eukaryotes PR Castello, PS David, T McClure, Z Crook, RO Poyton Cell metabolism 3 (4), 277-287, 2006 | 616 | 2006 |
Huntington's disease: can mice lead the way to treatment? ZR Crook, D Housman Neuron 69 (3), 423-435, 2011 | 261 | 2011 |
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets ZR Crook, GP Sevilla, D Friend, MY Brusniak, AD Bandaranayake, ... Nature communications 8 (1), 2244, 2017 | 83 | 2017 |
Miniproteins as a powerful modality in drug development ZR Crook, NW Nairn, JM Olson Trends in biochemical sciences 45 (4), 332-346, 2020 | 70 | 2020 |
Dysregulation of dopamine receptor D2 as a sensitive measure for Huntington disease pathology in model mice ZR Crook, DE Housman Proceedings of the National Academy of Sciences 109 (19), 7487-7492, 2012 | 43 | 2012 |
A TfR-binding cystine-dense peptide promotes blood–brain barrier penetration of bioactive molecules ZR Crook, E Girard, GP Sevilla, M Merrill, D Friend, PB Rupert, F Pakiam, ... Journal of molecular biology 432 (14), 3989-4009, 2020 | 31 | 2020 |
Surveying the landscape of Huntington's disease mechanisms, measurements, and medicines ZR Crook, DE Housman Journal of Huntington's disease 2 (4), 405-436, 2013 | 13 | 2013 |
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager ZR Crook, EJ Girard, GP Sevilla, MY Brusniak, PB Rupert, DJ Friend, ... Science translational medicine 14 (645), eabn0402, 2022 | 5 | 2022 |
Mammalian surface display screening of diverse cystine-dense peptide libraries for difficult-to-drug targets ZR Crook, GP Sevilla, AJ Mhyre, JM Olson Genotype Phenotype Coupling: Methods and Protocols, 363-396, 2020 | 4 | 2020 |
In vivo identification of therapeutic constructs from pooled candidates in HD model mice ZR Crook, DE Housman Journal of Huntington's Disease 2 (4), 437-441, 2013 | 1 | 2013 |
Advances in cystine-dense peptide (CDP) screening and therapeutic applications ZR Crook, EJ Girard, GP Sevilla, MY Brusniak, PB Rupert, DJ Friend, ... Cancer Research 82 (12_Supplement), 1043-1043, 2022 | | 2022 |