Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C NH Dryden, LR Broome, F Dudbridge, N Johnson, N Orr, S Schoenfelder, ... Genome research 24 (11), 1854-1868, 2014 | 276 | 2014 |
SF3B1 mutations constitute a novel therapeutic target in breast cancer SL Maguire, A Leonidou, P Wai, C Marchiò, CKY Ng, A Sapino, ... The Journal of pathology 235 (4), 571-580, 2015 | 243 | 2015 |
Comparative Genome Analysis and Gene Finding in Candida Species Using CGOB SL Maguire, SS OhÉigeartaigh, KP Byrne, MS Schröder, P O’Gaora, ... Molecular biology and evolution 30 (6), 1281-1291, 2013 | 125 | 2013 |
Capture Hi-C identifies putative target genes at 33 breast cancer risk loci JS Baxter, OC Leavy, NH Dryden, S Maguire, N Johnson, V Fedele, ... Nature communications 9 (1), 1028, 2018 | 108 | 2018 |
Conserved and divergent roles of Bcr1 and CFEM proteins in Candida parapsilosis and Candida albicans C Ding, GM Vidanes, SL Maguire, A Guida, JM Synnott, DR Andes, ... PloS one 6 (12), e28151, 2011 | 98 | 2011 |
Using RNA-seq to determine the transcriptional landscape and the hypoxic response of the pathogenic yeast Candida parapsilosis A Guida, C Lindstädt, SL Maguire, C Ding, DG Higgins, NJ Corton, ... BMC genomics 12, 1-14, 2011 | 82 | 2011 |
Evaluation of CDK12 protein expression as a potential novel biomarker for DNA damage response–targeted therapies in breast cancer K Naidoo, PT Wai, SL Maguire, F Daley, S Haider, D Kriplani, J Campbell, ... Molecular cancer therapeutics 17 (1), 306-315, 2018 | 62 | 2018 |
Zinc finger transcription factors displaced SREBP proteins as the major Sterol regulators during Saccharomycotina evolution SL Maguire, C Wang, LM Holland, F Brunel, C Neuveglise, JM Nicaud, ... PLoS genetics 10 (1), e1004076, 2014 | 60 | 2014 |
Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31. 2 N Orr, F Dudbridge, N Dryden, S Maguire, D Novo, E Perrakis, N Johnson, ... Human molecular genetics 24 (10), 2966-2984, 2015 | 59 | 2015 |
Three‐dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model SL Maguire, B Peck, PT Wai, J Campbell, H Barker, A Gulati, F Daley, ... The Journal of Pathology 240 (3), 315-328, 2016 | 41 | 2016 |
Common susceptibility loci for male breast cancer S Maguire, E Perraki, K Tomczyk, ME Jones, O Fletcher, M Pugh, T Winter, ... JNCI: Journal of the National Cancer Institute 113 (4), 453-461, 2021 | 17 | 2021 |
Assessment of structural chromosomal instability phenotypes as biomarkers of carboplatin response in triple negative breast cancer: the TNT trial O Sipos, H Tovey, J Quist, S Haider, S Nowinski, P Gazinska, ... Annals of Oncology 32 (1), 58-65, 2021 | 15 | 2021 |
Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells F Amoroso, K Glass, R Singh, F Liberal, RE Steele, S Maguire, ... Scientific Reports 11 (1), 4252, 2021 | 12 | 2021 |
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element JS Baxter, N Johnson, K Tomczyk, A Gillespie, S Maguire, R Brough, ... The American Journal of Human Genetics 108 (7), 1190-1203, 2021 | 11 | 2021 |
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers N Johnson, S Maguire, A Morra, PM Kapoor, K Tomczyk, ME Jones, ... British journal of cancer 124 (4), 842-854, 2021 | 9 | 2021 |
3D functional genomics screens identify CREBBP as a targetable driver in aggressive triple-negative breast cancer B Peck, P Bland, I Mavrommati, G Muirhead, H Cottom, PT Wai, ... Cancer research 81 (4), 847-859, 2021 | 9 | 2021 |
VPRBP functions downstream of the androgen receptor and OGT to restrict p53 activation in prostate cancer N Poulose, N Forsythe, A Polonski, G Gregg, S Maguire, M Fuchs, ... Molecular Cancer Research 20 (7), 1047-1060, 2022 | 7 | 2022 |
Activation of innate-adaptive immune machinery by poly (I: C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer SM Corry, AMB McCorry, TRM Lannagan, NA Leonard, NC Fisher, ... Gut 71 (12), 2502-2517, 2022 | 5 | 2022 |
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer SB Malla, RM Byrne, MW Lafarge, SM Corry, NC Fisher, PK Tsantoulis, ... Nature Genetics, 1-15, 2024 | 2 | 2024 |
Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis A Amin, M Badenes, J Tüshaus, É de Carvalho, E Burbridge, P Faísca, ... Molecular Metabolism 73, 101731, 2023 | 2 | 2023 |