Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase DO Ozgun, C Yamali, HI Gul, P Taslimi, I Gulcin, T Yanik, CT Supuran Journal of enzyme inhibition and medicinal chemistry 31 (6), 1498-1501, 2016 | 149 | 2016 |
Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes K Kucukoglu, HI Gul, P Taslimi, I Gulcin, CT Supuran Bioorganic chemistry 86, 316-321, 2019 | 141 | 2019 |
Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity DO Ozgun, HI Gul, C Yamali, H Sakagami, I Gulcin, M Sukuroglu, ... Bioorganic chemistry 84, 511-517, 2019 | 134 | 2019 |
Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides HI Gul, M Tugrak, H Sakagami, P Taslimi, I Gulcin, CT Supuran Journal of Enzyme Inhibition and Medicinal Chemistry 31 (6), 1619-1624, 2016 | 130 | 2016 |
Synthesis, molecular modeling, and biological evaluation of 4‐[5‐aryl‐3‐(thiophen‐2‐yl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl] benzenesulfonamides toward … C Yamali, HI Gul, A Ece, P Taslimi, I Gulcin Chemical biology & drug design 91 (4), 854-866, 2018 | 128 | 2018 |
New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors HI Gul, C Yamali, H Sakagami, A Angeli, J Leitans, A Kazaks, K Tars, ... Bioorganic Chemistry 77, 411-419, 2018 | 126 | 2018 |
Synthesis, carbonic anhydrase I and II inhibition studies of the 1, 3, 5-trisubstituted-pyrazolines HI Gul, E Mete, P Taslimi, I Gulcin, CT Supuran Journal of enzyme inhibition and medicinal chemistry 32 (1), 189-192, 2017 | 108 | 2017 |
Cytotoxic activities of mono and bis Mannich bases derived from acetophenone against Renca and Jurkat cells HI Gul, J Vepsalainen, M Gul, E Erciyas, O Hanninen Pharmaceutica Acta Helvetiae 74 (4), 393-398, 2000 | 97 | 2000 |
A novel pyrazoline-based fluorometric “turn-off” sensing for Hg2+ E Bozkurt, HI Gul Sensors and Actuators B: Chemical 255, 814-825, 2018 | 95 | 2018 |
Antifungal evaluation of bis Mannich bases derived from acetophenones and their corresponding piperidinols and stability studies HI Gul, T Ojanen, O Hänninen Biological and Pharmaceutical Bulletin 25 (10), 1307-1310, 2002 | 91 | 2002 |
Antimicrobial evaluation of some styryl ketone derivatives and related thiol adducts E Erciyas, EH Inci, G Cosar Journal of Pharmaceutical Sciences 83 (4), 545-548, 1994 | 84 | 1994 |
Synthesis of 4-(2-substituted hydrazinyl) benzenesulfonamides and their carbonic anhydrase inhibitory effects HI Gul, K Kucukoglu, C Yamali, S Bilginer, H Yuca, I Ozturk, P Taslimi, ... Journal of enzyme inhibition and medicinal chemistry 31 (4), 568-573, 2016 | 76 | 2016 |
Solvent and substituent effect on the photophysical properties of pyrazoline derivatives: A spectroscopic study E Bozkurt, HI Gul, E Mete Journal of Photochemistry and Photobiology A: Chemistry 352, 35-42, 2018 | 74 | 2018 |
Anti-inflammatory activity of 3-benzoyl-1-methyl-4-phenyl-4-piperidinol hydrochloride H Suleyman, HI Gul, M Asoglu Pharmacological research 47 (6), 471-475, 2003 | 70 | 2003 |
Antimicrobial evaluation of some Mannich bases of acetophenones and representative quaternary derivatives HI Gul, AA Denizci, E Erciyas Arzneimittelforschung 52 (10), 773-777, 2002 | 70 | 2002 |
Synthesis of some mono-Mannich bases and corresponding azine derivatives and evaluation of their anticonvulsant activity HI Gul, U Calis, J Vepsalainen Arzneimittelforschung 54 (07), 359-364, 2004 | 69 | 2004 |
Antifungal activity of some mono, bis and quaternary Mannich bases derived from acetophenone HI Gul, T Ojanen, J Vepsalainen, M Gul, E Erciyas, O Hanninen Arzneimittelforschung 51 (01), 72-75, 2001 | 68 | 2001 |
Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of … C Yamali, HI Gul, C Kazaz, S Levent, I Gulcin Bioorganic Chemistry 96, 103627, 2020 | 67 | 2020 |
Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors M Tugrak, HI Gul, K Bandow, H Sakagami, I Gulcin, Y Ozkay, CT Supuran Bioorganic Chemistry 90, 103095, 2019 | 66 | 2019 |
New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno [1, 2-b] pyridin-5-ones M Tugrak, HI Gul, H Sakagami, I Gulcin, CT Supuran Bioorganic chemistry 81, 433-439, 2018 | 65 | 2018 |